Structured Practical Experiential Program III
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Questions and Answers

What physiological process is inhibited by this medication, according to the information provided?

  • Calcium channel activity in vascular smooth muscle
  • Potassium excretion in the nephron
  • Angiotensin-converting enzyme, reducing vasoconstriction (correct)
  • Sodium reabsorption in the kidneys

Which of the following is a listed adverse effect of the medication?

  • Hyperkalemia (correct)
  • Fluid retention
  • Peripheral edema
  • Tachycardia

What is the primary therapeutic use of this medication?

  • Hyperlipidemia
  • Hypertension (correct)
  • Angina pectoris
  • Arrhythmia

What is correct administration route of the medication?

<p>Oral (A)</p> Signup and view all the answers

Which condition is a contraindication for the use of this medication?

<p>Severe renal impairment (C)</p> Signup and view all the answers

Which element is primarily associated with a medication's intended therapeutic applications?

<p>Indication (D)</p> Signup and view all the answers

What information is commonly included on a prescription?

<p>Route of administration (B)</p> Signup and view all the answers

What does 'Contraindication' refer to in the context of medication?

<p>Conditions where the drug should not be used (B)</p> Signup and view all the answers

What is the significance of knowing the 'Mechanism of Action' of a drug?

<p>It explains how the drug produces its effects. (A)</p> Signup and view all the answers

Which piece of information specifies the amount of medication in a single dose?

<p>Strength (C)</p> Signup and view all the answers

What is the primary mechanism of action of Candesartan?

<p>Blocking angiotensin II receptors. (A)</p> Signup and view all the answers

Which medication class does Hydrochlorothiazide belong to?

<p>Thiazide diuretic (A)</p> Signup and view all the answers

What is the standard oral dosage of Cantab Plus?

<p>20 mg/12.5 mg (A)</p> Signup and view all the answers

Which of the following is a contraindication for using Cantab Plus?

<p>Pregnancy. (B)</p> Signup and view all the answers

Identify a potential side effect associated with Cantab Plus.

<p>Hyperkalemia. (D)</p> Signup and view all the answers

What is the mechanism of action of Olmesartan?

<p>Blocks angiotensin II receptors; increases diuresis. (C)</p> Signup and view all the answers

What class of drug is Hydrochlorothiazide?

<p>Thiazide diuretic (D)</p> Signup and view all the answers

What is a contraindication for taking Olmesartan + Hydrochlorothiazide?

<p>Pregnancy (B)</p> Signup and view all the answers

What is a potential side effect of Olmesartan + Hydrochlorothiazide?

<p>Hyperkalemia (B)</p> Signup and view all the answers

What is the route of administration for Olmesartan + Hydrochlorothiazide?

<p>Oral (C)</p> Signup and view all the answers

What are the active ingredients in Farcopril Plus?

<p>Fosinopril and Hydrochlorothiazide (A)</p> Signup and view all the answers

Which of the following is NOT a listed adverse effect of Farcopril Plus?

<p>Hypertension (A)</p> Signup and view all the answers

Which of the following conditions is listed as a contraindication for using Farcopril Plus?

<p>Pregnancy (C)</p> Signup and view all the answers

What dosage strength of Fosinopril and Hydrochlorothiazide is in each tablet of Farcopril Plus?

<p>16 mg / 12.5 mg (C)</p> Signup and view all the answers

What are the two listed conditions that require caution when using Farcopril Plus?

<p>Severe hepatic/renal impairment (B)</p> Signup and view all the answers

What class of medication does hydrochlorothiazide belong to?

<p>Thiazide diuretic (C)</p> Signup and view all the answers

What is the primary effect of hydrochlorothiazide that contributes to its antihypertensive effect?

<p>Increases diuresis (C)</p> Signup and view all the answers

What is the name of the drug combination that includes Candesartan and Hydrochlorothiazide?

<p>Hicand plus (A)</p> Signup and view all the answers

What is the main therapeutic benefit of combining Candesartan and Hydrochlorothiazide in a single medication?

<p>Synergistic antihypertensive effect (C)</p> Signup and view all the answers

Flashcards

Prescription

A doctor's authorization for a patient to obtain a specific medication.

Route of Administration

The method by which a drug is delivered to the body (e.g., oral, intravenous).

Contraindication

A specific situation in which a drug should not be used due to potential harm.

Side Effect

An unwanted or unexpected reaction to a medication.

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Mechanism Of Action

The process by which a drug produces its effects in the body.

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Oral administration

Taking medication by mouth as a route of delivery.

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Dosage of medication

10 mg/12.5 mg refers to the specific amounts of the drug given.

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Hypertension

A condition characterized by elevated blood pressure.

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Angiotensin-converting enzyme (ACE) inhibitors

Drugs that reduce vasoconstriction and lower blood pressure.

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Side effects of ACE inhibitors

Dizziness, hypotension, and hyperkalemia can occur.

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Fosinopril

An ACE inhibitor used to treat high blood pressure and heart failure.

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Hydrochlorothiazide

A thiazide diuretic that helps reduce high blood pressure by eliminating excess fluid.

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Farcopril Plus

A combination medication of Fosinopril and Hydrochlorothiazide.

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Indications for use

Used for severe hepatic/renal impairment and during pregnancy with caution.

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Olmesartan

An angiotensin II receptor blocker (ARB) used to treat hypertension.

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Diuresis

Increased production of urine, often as a result of medication.

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Adverse Effects

Undesired effects of a medication, such as hypotension and hyperkalemia.

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Angiotensin II Receptors

Receptors that bind angiotensin II, involved in blood pressure regulation.

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Candesartan

An angiotensin II receptor blocker (ARB) used to treat hypertension.

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Hicand plus

A combination medication of Candesartan and Hydrochlorothiazide for hypertension treatment.

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Cantab Plus

A combination medication of Candesartan and Hydrochlorothiazide for treating hypertension.

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Hyperkalemia

A condition of elevated potassium levels in the blood, which can be a side effect of certain medications.

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Study Notes

Structured Practical Experiential Program III (SPEP III)

  • Trade Name/Generic Name/Class: Different combinations of drugs are listed, including ACE inhibitors, Thiazide Diuretics, and ARBs.

  • Mechanism of Action:

    • Fosinopril (ACE Inhibitor): Inhibits angiotensin-converting enzyme, reducing vasoconstriction and increasing diuresis.
    • Hydrochlorothiazide (Thiazide Diuretic): Reduces sodium reabsorption, increasing diuresis.
    • Candesartan (ARB): Blocks angiotensin II receptors, increasing diuresis.
    • Olmesartan (ARB): Blocks angiotensin II receptors, increasing diuresis.
  • Indications (main uses): Hypertension is a common indication for all the listed drug combinations.

  • Side Effects: Dizziness, hypotension, hyperkalemia, are listed as possible side effects.

  • Contraindications: Pregnancy, severe renal impairment.

  • Dosage/Strength: Strengths and dosages vary across the different drug combinations (e.g., 10mg/12.5mg, 16mg/12.5mg, 20mg/12.5mg)

  • Route of Administration: Oral.

  • Prescribing Agent/Company: Different pharmaceutical companies are listed.

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Test your knowledge on drug combinations used for hypertension, including ACE inhibitors, Thiazide Diuretics, and ARBs. Explore their mechanisms of action, indications, side effects, and contraindications in this comprehensive quiz. Perfect for students in pharmacology and medicine.

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