Stroke and Its Causes Quiz
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Questions and Answers

What is the mechanism of action of Alteplase?

  • Plasminogen activated by Urokinase (correct)
  • Inhibition of COX-1
  • Inhibition of factor Xa
  • Thrombolytic agents

Which adverse effect is associated with the use of thrombolytic agents?

  • Bleeding (correct)
  • Bronchospasm
  • Reye syndrome
  • GI disturbance

What is the primary adverse effect of aspirin?

  • GI disturbance
  • Bronchospasm
  • Reye syndrome
  • Bleeding (correct)

Which condition is associated with swelling of the liver and brain?

<p>Reye syndrome (A)</p> Signup and view all the answers

What is the mechanism of action of warfarin?

<p>Vitamin K antagonist (B)</p> Signup and view all the answers

What is the primary adverse effect of Dabigatran etexilate?

<p>Bleeding (D)</p> Signup and view all the answers

What is the primary mechanism of action of Heparin?

<p>Accelerating neutralization of coagulation factors by antithrombin (B)</p> Signup and view all the answers

Which drug is a prodrug of the active moiety dabigatran and acts as an oral direct thrombin inhibitor?

<p>Dabigatran etexilate (B)</p> Signup and view all the answers

How does Low Molecular Weight Heparins (LMWH) exert its anticoagulant activity?

<p>By activating antithrombin and catalyzing factor Xa inhibition more than thrombin inhibition. (A)</p> Signup and view all the answers

What should be frequently monitored and adjusted when using warfarin therapy?

<p>Prothrombin time (PT) (C)</p> Signup and view all the answers

Which drug should be avoided in severe renal dysfunction due to the risk of bleeding related to declining kidney function?

<p>Rivaroxaban &amp; Apixaban (C)</p> Signup and view all the answers

What is the primary adverse effect associated with Thrombolytic agents?

<p>Bleeding (B)</p> Signup and view all the answers

What is the main cause of Ischemic stroke (IS)?

<p>Lack of blood reaching part of the brain (C)</p> Signup and view all the answers

What is the primary symptom developed in a few minutes in Ischemic stroke (IS)?

<p>Loss of strength or sensation on one side of the body (B)</p> Signup and view all the answers

What is a common risk factor for Hemorrhagic stroke (HS)?

<p>Hypertension (C)</p> Signup and view all the answers

How is Hemostatic process related to preventing Ischemic stroke?

<p>It involves waking up suddenly from sleep (A)</p> Signup and view all the answers

What is a sign to recognize if someone is having a stroke?

<p>&quot;Arm Drift&quot; (C)</p> Signup and view all the answers

What percentage of strokes are caused by ruptures of blood vessels?

<p>13% (C)</p> Signup and view all the answers

What time do most Ischemic strokes occur?

<p>At night or first thing in the morning (B)</p> Signup and view all the answers

What is a common factor related to Hemorrhagic stroke?

<p>Alcohol consumption (C)</p> Signup and view all the answers

What does CPD stand for?

<p>Cerebral Perfusion Deficit (B)</p> Signup and view all the answers

What is an example of a symptom associated with Hemorrhagic stroke?

<p>Severe headache (C)</p> Signup and view all the answers

Which medication is a vitamin K antagonist and is rapidly absorbed after oral administration with little individual patient variation?

<p>Warfarin (D)</p> Signup and view all the answers

What is the primary adverse effect associated with the use of thrombolytic agents?

<p>Hemorrhage (B)</p> Signup and view all the answers

Which drug acts mainly by accelerating the rate of the neutralization of certain activated coagulation factors by antithrombin?

<p>Heparin (B)</p> Signup and view all the answers

What is a serious pathological condition associated with swelling of the liver and brain?

<p>Reye syndrome (B)</p> Signup and view all the answers

Which drug should be avoided in severe renal dysfunction due to the risk of bleeding related to declining kidney function?

<p>Dabigatran etexilate (B)</p> Signup and view all the answers

What is the mechanism of action of Alteplase?

<p>Plasminogen activated by Urokinase. (A)</p> Signup and view all the answers

What is a common adverse effect associated with the use of Dabigatran etexilate?

<p>Bleeding (C)</p> Signup and view all the answers

What should be frequently monitored and adjusted when using warfarin therapy?

<p>Prothrombin time (PT) (A)</p> Signup and view all the answers

How do Low Molecular Weight Heparins (LMWH) exert their anticoagulant activity?

<p>By activating antithrombin and catalyzing factor Xa inhibition more than thrombin inhibition. (D)</p> Signup and view all the answers

Which drug is administered intravenously to achieve immediate anticoagulation?

<p>Heparin (C)</p> Signup and view all the answers

What is a common adverse effect associated with Thrombolytic agents?

<p>Hemorrhage (C)</p> Signup and view all the answers

'Purple toe syndrome' is an adverse effect associated with which medication?

<p>Warfarin (C)</p> Signup and view all the answers

What is the primary cause of Ischemic stroke (IS)?

<p>Sudden blockage of blood flow to part of the brain (A)</p> Signup and view all the answers

What is a common risk factor for Hemorrhagic stroke (HS)?

<p>Alcohol consumption (B)</p> Signup and view all the answers

What is the primary symptom developed in a few minutes in Ischemic stroke (IS)?

<p>Loss of strength or sensation on one side of the body (C)</p> Signup and view all the answers

How is Hemostatic process related to preventing Ischemic stroke?

<p>By preventing excessive bleeding in the brain (D)</p> Signup and view all the answers

"Arm Drift" is used as a sign to recognize if someone is having a stroke. What does it refer to?

<p>'Drifting' movement of one arm when extended horizontally with eyes closed (A)</p> Signup and view all the answers

Which condition is associated with swelling of the liver and brain?

<p>Stroke (C)</p> Signup and view all the answers

What percentage of strokes are caused by ruptures of blood vessels?

<p>13% (D)</p> Signup and view all the answers

What should be done when assessing if someone might be having a stroke?

<p>Ask them to repeat a simple sentence. (C)</p> Signup and view all the answers

What does CPD stand for?

<p>Cerebral Perfusion Deficit (A)</p> Signup and view all the answers

What is an example of a symptom associated with Hemorrhagic stroke?

<p>Sudden severe headache and nausea/vomiting (C)</p> Signup and view all the answers

What time do most Ischemic strokes occur?

<p>At night or first morning after waking up from sleep suddenly (C)</p> Signup and view all the answers

Which drug acts mainly by accelerating the rate of neutralization of certain activated coagulation factors by antithrombin?

<p>Heparin (A)</p> Signup and view all the answers

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