Stroke and Its Causes Quiz
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Questions and Answers

What is the mechanism of action of Alteplase?

  • Plasminogen activated by Urokinase (correct)
  • Inhibition of COX-1
  • Inhibition of factor Xa
  • Thrombolytic agents

    • Which adverse effect is associated with the use of thrombolytic agents?

  • Bleeding (correct)
  • Bronchospasm
  • Reye syndrome
  • GI disturbance

    • What is the primary adverse effect of aspirin?

  • GI disturbance
  • Bronchospasm
  • Reye syndrome
  • Bleeding (correct)

    • Which condition is associated with swelling of the liver and brain?

    <p>Reye syndrome</p> Signup and view all the answers

    What is the mechanism of action of warfarin?

    <p>Vitamin K antagonist</p> Signup and view all the answers

    What is the primary adverse effect of Dabigatran etexilate?

    <p>Bleeding</p> Signup and view all the answers

    What is the primary mechanism of action of Heparin?

    <p>Accelerating neutralization of coagulation factors by antithrombin</p> Signup and view all the answers

    Which drug is a prodrug of the active moiety dabigatran and acts as an oral direct thrombin inhibitor?

    <p>Dabigatran etexilate</p> Signup and view all the answers

    How does Low Molecular Weight Heparins (LMWH) exert its anticoagulant activity?

    <p>By activating antithrombin and catalyzing factor Xa inhibition more than thrombin inhibition.</p> Signup and view all the answers

    What should be frequently monitored and adjusted when using warfarin therapy?

    <p>Prothrombin time (PT)</p> Signup and view all the answers

    Which drug should be avoided in severe renal dysfunction due to the risk of bleeding related to declining kidney function?

    <p>Rivaroxaban &amp; Apixaban</p> Signup and view all the answers

    What is the primary adverse effect associated with Thrombolytic agents?

    <p>Bleeding</p> Signup and view all the answers

    What is the main cause of Ischemic stroke (IS)?

    <p>Lack of blood reaching part of the brain</p> Signup and view all the answers

    What is the primary symptom developed in a few minutes in Ischemic stroke (IS)?

    <p>Loss of strength or sensation on one side of the body</p> Signup and view all the answers

    What is a common risk factor for Hemorrhagic stroke (HS)?

    <p>Hypertension</p> Signup and view all the answers

    How is Hemostatic process related to preventing Ischemic stroke?

    <p>It involves waking up suddenly from sleep</p> Signup and view all the answers

    What is a sign to recognize if someone is having a stroke?

    <p>&quot;Arm Drift&quot;</p> Signup and view all the answers

    What percentage of strokes are caused by ruptures of blood vessels?

    <p>13%</p> Signup and view all the answers

    What time do most Ischemic strokes occur?

    <p>At night or first thing in the morning</p> Signup and view all the answers

    What is a common factor related to Hemorrhagic stroke?

    <p>Alcohol consumption</p> Signup and view all the answers

    What does CPD stand for?

    <p>Cerebral Perfusion Deficit</p> Signup and view all the answers

    What is an example of a symptom associated with Hemorrhagic stroke?

    <p>Severe headache</p> Signup and view all the answers

    Which medication is a vitamin K antagonist and is rapidly absorbed after oral administration with little individual patient variation?

    <p>Warfarin</p> Signup and view all the answers

    What is the primary adverse effect associated with the use of thrombolytic agents?

    <p>Hemorrhage</p> Signup and view all the answers

    Which drug acts mainly by accelerating the rate of the neutralization of certain activated coagulation factors by antithrombin?

    <p>Heparin</p> Signup and view all the answers

    What is a serious pathological condition associated with swelling of the liver and brain?

    <p>Reye syndrome</p> Signup and view all the answers

    Which drug should be avoided in severe renal dysfunction due to the risk of bleeding related to declining kidney function?

    <p>Dabigatran etexilate</p> Signup and view all the answers

    What is the mechanism of action of Alteplase?

    <p>Plasminogen activated by Urokinase.</p> Signup and view all the answers

    What is a common adverse effect associated with the use of Dabigatran etexilate?

    <p>Bleeding</p> Signup and view all the answers

    What should be frequently monitored and adjusted when using warfarin therapy?

    <p>Prothrombin time (PT)</p> Signup and view all the answers

    How do Low Molecular Weight Heparins (LMWH) exert their anticoagulant activity?

    <p>By activating antithrombin and catalyzing factor Xa inhibition more than thrombin inhibition.</p> Signup and view all the answers

    Which drug is administered intravenously to achieve immediate anticoagulation?

    <p>Heparin</p> Signup and view all the answers

    What is a common adverse effect associated with Thrombolytic agents?

    <p>Hemorrhage</p> Signup and view all the answers

    'Purple toe syndrome' is an adverse effect associated with which medication?

    <p>Warfarin</p> Signup and view all the answers

    What is the primary cause of Ischemic stroke (IS)?

    <p>Sudden blockage of blood flow to part of the brain</p> Signup and view all the answers

    What is a common risk factor for Hemorrhagic stroke (HS)?

    <p>Alcohol consumption</p> Signup and view all the answers

    What is the primary symptom developed in a few minutes in Ischemic stroke (IS)?

    <p>Loss of strength or sensation on one side of the body</p> Signup and view all the answers

    How is Hemostatic process related to preventing Ischemic stroke?

    <p>By preventing excessive bleeding in the brain</p> Signup and view all the answers

    "Arm Drift" is used as a sign to recognize if someone is having a stroke. What does it refer to?

    <p>'Drifting' movement of one arm when extended horizontally with eyes closed</p> Signup and view all the answers

    Which condition is associated with swelling of the liver and brain?

    <p>Stroke</p> Signup and view all the answers

    What percentage of strokes are caused by ruptures of blood vessels?

    <p>13%</p> Signup and view all the answers

    What should be done when assessing if someone might be having a stroke?

    <p>Ask them to repeat a simple sentence.</p> Signup and view all the answers

    What does CPD stand for?

    <p>Cerebral Perfusion Deficit</p> Signup and view all the answers

    What is an example of a symptom associated with Hemorrhagic stroke?

    <p>Sudden severe headache and nausea/vomiting</p> Signup and view all the answers

    What time do most Ischemic strokes occur?

    <p>At night or first morning after waking up from sleep suddenly</p> Signup and view all the answers

    Which drug acts mainly by accelerating the rate of neutralization of certain activated coagulation factors by antithrombin?

    <p>Heparin</p> Signup and view all the answers

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