Podcast
Questions and Answers
What is the generic name and drug class of Stiolto?
What is the generic name and drug class of Stiolto?
What is the efficacy of Stiolto?
What is the efficacy of Stiolto?
It is effective at reducing the need for rescue inhalers.
What improvement did patients on Stiolto achieve compared to Spiriva Respimat?
What improvement did patients on Stiolto achieve compared to Spiriva Respimat?
Superior improvement in lung function.
What is Stiolto indicated for?
What is Stiolto indicated for?
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Stiolto is contraindicated in patients with asthma without a long-term asthma control medication.
Stiolto is contraindicated in patients with asthma without a long-term asthma control medication.
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Which of the following are common side effects of Stiolto? (Select all that apply)
Which of the following are common side effects of Stiolto? (Select all that apply)
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What is the recommended dosing for Stiolto?
What is the recommended dosing for Stiolto?
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How is Stiolto administered?
How is Stiolto administered?
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What is the mechanism of action of Stiolto?
What is the mechanism of action of Stiolto?
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What is the coverage status of Stiolto?
What is the coverage status of Stiolto?
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What type of materials are available for Stiolto?
What type of materials are available for Stiolto?
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What should be considered when using other drugs with Stiolto?
What should be considered when using other drugs with Stiolto?
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Most patients get Stiolto for free.
Most patients get Stiolto for free.
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Study Notes
Stiolto Overview
- Stiolto is a combination of tiotropium bromide and olodaterol, classified as a bronchodilator.
- It is used for long-term maintenance treatment of airflow obstruction in chronic obstructive pulmonary disease (COPD).
Efficacy
- Demonstrates effectiveness in reducing the reliance on rescue inhalers for COPD patients.
- In clinical trials, patients using Stiolto showed superior lung function improvement compared to those using Spiriva Respimat.
Indications
- Specifically indicated for once-daily maintenance therapy in patients with COPD, encompassing chronic bronchitis and emphysema.
Safety Information
- Contraindicated in patients with a history of hypersensitivity to tiotropium, ipratropium, olodaterol, or any components of Stiolto.
- LABAs, including Stiolto, are not recommended for asthma patients without concurrent long-term control medications.
Common Side Effects
- Frequently reported side effects include:
- Nasopharyngitis (sinus irritation and sore throat)
- Cough
- Back pain
- Dehydration
- Dizziness
- Insomnia
- Glaucoma
- Blurred vision
Dosing and Administration
- Administered as two puffs once daily.
- Delivered through an inhalation spray method for convenient use.
Mechanism of Action
- Olodaterol acts as a long-acting beta2-adrenergic agonist (LABA).
- It activates beta2-adrenoceptors upon inhalation, exerting its pharmacological effects effectively.
Coverage and Accessibility
- Considered accessible through most commercial insurance plans (over 80%) and Medicare Part D plans (over 70%).
- High availability at the lowest branded copay for a majority of patients.
Educational Materials
- Various brochures and resources are available for healthcare providers and patients regarding the proper use and benefits of Stiolto.
Drug Interactions
- Caution is advised when administering with adrenergic drugs as synergetic effects may occur.
- Concurrent use of xanthine derivatives, steroids, or diuretics may enhance the hypokalemic effects of olodaterol.
Cost
- Patients often access this medication at no charge, indicating high coverage and affordability.
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Description
Test your knowledge about Stiolto, including its generic name, drug class, efficacy, and clinical trial comparisons. This quiz will help reinforce what you need to know about this important bronchodilator used for respiratory conditions.
