10 Questions
What is the process by which leukocytes escape from venules and small veins?
Transmigration of leukocytes
What is the name of the unidirectional attraction of leukocytes towards the site of inflammation?
Chemotaxis
Which chemical mediator increases vascular permeability and activates chemotaxis during inflammation?
Complement system (C5a)
What is the process of engulfment and internalization of particulate material by specialized cells?
Phagocytosis
Which cytokines are important mediators of the acute-phase response during systemic inflammation?
TNF, IL-1, and IL-6
What are the cell adhesion molecules involved in the binding of leukocytes with endothelial cells?
Selectins, immunoglobulins, integrins
Describe the process of diapedesis in the context of leukocyte movement.
Leukocytes extend pseudopodia through the vascular wall to escape from venules and small veins.
Explain the mechanism of leukocyte emigration involving the endothelial junctions.
Leukocyte emigration occurs via widening of interendothelial junctions after endothelial cell contractions.
What are the most important chemotactic factors for neutrophils in the process of chemotaxis?
Components of the complement system (C5a), leukotriene B4, cytokines (IL-8)
Which cells are involved in the process of phagocytosis and what type of material do they engulf?
Polymorphonuclear leukocytes (especially neutrophils), monocytes, tissue macrophages; invading microorganisms, damaged cells, tissue debris
Learn about the stimuli that cause cellular adaptation or injury and the resulting changes in cells. Explore the concept of cellular adaptation when cells are exposed to injurious agents.
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