Stimulants in Medical Treatment

What is the maximum dosage of Methylphenidate ER (Concerta) for adults with ADHD?

72 mg/d

What is the recommended starting dose of Dexmethylphenidate (Focalin XR) for children aged 6 and up?

5 mg/d

What is the maximum daily dose of Modafinil (Provigil) for the treatment of ADHD, narcolepsy, and excessive sleepiness?

400 mg

Which of the following is NOT a reason for the cautious use of stimulant agents in emotionally unstable patients?

They are more likely to experience insomnia. Signup and view all the answers

What is the recommended starting dose of Atomoxetine (Strattera) for adults and children over 70 kg?

40 mg/d Signup and view all the answers

Which of the following is a potential side effect of abruptly stopping stimulant medications?

Extreme fatigue and mental depression Signup and view all the answers

What is the recommended timing for taking Modafinil (Provigil) for the treatment of shift work sleep disorder?

1 hour before work Signup and view all the answers

What is the recommended maximum daily dose of Dexmethylphenidate (Focalin XR) for adults and children?

20 mg/d Signup and view all the answers

Why may some children do better on a sustained-release formulation of methylphenidate?

To provide symptom coverage in the afternoon and evening Signup and view all the answers

What is the recommended starting dose of Methylphenidate ER (Metadate ER) for patients aged 6 and up?

10 mg q a.m. Signup and view all the answers

What is the primary mechanism of action of stimulant drugs used to treat ADHD and narcolepsy?

They act as dopamine agonists and indirectly release and prevent the reuptake of dopamine, serotonin, and norepinephrine. Signup and view all the answers

Which of the following stimulant drugs is less commonly used to treat ADHD and narcolepsy compared to the others mentioned?

Methamphetamine Signup and view all the answers

What is one of the key therapeutic effects of stimulant drugs used to treat ADHD and narcolepsy?

They have an anorexiant (appetite-suppressing) effect. Signup and view all the answers

Which of the following is an alternative to stimulant drugs for the treatment of ADHD?

Atomoxetine Signup and view all the answers

What is one reason why amphetamines are notorious as street drugs of abuse?

They have the same therapeutic uses as stimulants approved for ADHD and narcolepsy. Signup and view all the answers

How do over-the-counter cold medicines containing caffeine affect the stimulant effects of other stimulant drugs?

They have additive stimulant effects when combined with other stimulant drugs. Signup and view all the answers

What brain regions make up the reward center stimulated by certain drugs?

Cerebral cortex, brainstem, reticular activating system Signup and view all the answers

How are drugs like dextroamphetamine and methylphenidate metabolized in the liver?

By de-esterification Signup and view all the answers

What is a common adverse reaction associated with the use of stimulants?

Insomnia Signup and view all the answers

Which condition is a contraindication for the use of stimulants?

Hyperthyroidism Signup and view all the answers

How does urine acidity affect the excretion of amphetamine?

Increased alkalinity increases its half-life Signup and view all the answers

What is a significant drug interaction risk when taking stimulants within 14 days of an MAOI?

Hypertensive crisis Signup and view all the answers

What is a precaution regarding the use of Concerta in patients with certain disorders?

Increased risk of obstructive esophageal disorders Signup and view all the answers

Which of the following statements about stimulant prescriptions is true?

States may have mechanisms for providing more than one month's prescription at a time. Signup and view all the answers

What is the peak duration of action for methylphenidate HCl?

4-6 hours Signup and view all the answers

Which of the following is a possible effect when stimulants are taken with MAOIs?

Increased risk of hypertensive crisis and stroke Signup and view all the answers

What is the maximum recommended daily dose of dextroamphetamine for children over 5 years old?

40 mg/day Signup and view all the answers

Which of the following statements about atomoxetine is true?

It is primarily excreted through the kidneys. Signup and view all the answers

What is the recommended starting dose of lisdexamfetamine for a 10-year-old child with ADHD?

30 mg once daily Signup and view all the answers

Which of the following statements about the Daytrana patch is false?

The application site does not need to be rotated. Signup and view all the answers

According to the drug interactions table, which of the following drugs should be avoided when taking stimulants?

Tricyclic antidepressants (TCAs) Signup and view all the answers

What is the recommended maximum daily dose of Ritalin (methylphenidate HCl) for adults?

60 mg/day Signup and view all the answers

Which of the following statements about drug interactions with stimulants is false?

Acidifying agents may increase the effect of stimulants. Signup and view all the answers