Stimulants in Medical Treatment
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Questions and Answers

What is the maximum dosage of Methylphenidate ER (Concerta) for adults with ADHD?

  • 36 mg/d
  • 72 mg/d (correct)
  • 18 mg/d
  • 54 mg/d

    • What is the recommended starting dose of Dexmethylphenidate (Focalin XR) for children aged 6 and up?

  • 5 mg/d (correct)
  • 2.5 mg bid
  • 20 mg/d
  • 10 mg/d

    • What is the maximum daily dose of Modafinil (Provigil) for the treatment of ADHD, narcolepsy, and excessive sleepiness?

  • 200 mg
  • 500 mg
  • 400 mg (correct)
  • 300 mg

    • Which of the following is NOT a reason for the cautious use of stimulant agents in emotionally unstable patients?

    <p>They are more likely to experience insomnia.</p> Signup and view all the answers

    What is the recommended starting dose of Atomoxetine (Strattera) for adults and children over 70 kg?

    <p>40 mg/d</p> Signup and view all the answers

    Which of the following is a potential side effect of abruptly stopping stimulant medications?

    <p>Extreme fatigue and mental depression</p> Signup and view all the answers

    What is the recommended timing for taking Modafinil (Provigil) for the treatment of shift work sleep disorder?

    <p>1 hour before work</p> Signup and view all the answers

    What is the recommended maximum daily dose of Dexmethylphenidate (Focalin XR) for adults and children?

    <p>20 mg/d</p> Signup and view all the answers

    Why may some children do better on a sustained-release formulation of methylphenidate?

    <p>To provide symptom coverage in the afternoon and evening</p> Signup and view all the answers

    What is the recommended starting dose of Methylphenidate ER (Metadate ER) for patients aged 6 and up?

    <p>10 mg q a.m.</p> Signup and view all the answers

    What is the primary mechanism of action of stimulant drugs used to treat ADHD and narcolepsy?

    <p>They act as dopamine agonists and indirectly release and prevent the reuptake of dopamine, serotonin, and norepinephrine.</p> Signup and view all the answers

    Which of the following stimulant drugs is less commonly used to treat ADHD and narcolepsy compared to the others mentioned?

    <p>Methamphetamine</p> Signup and view all the answers

    What is one of the key therapeutic effects of stimulant drugs used to treat ADHD and narcolepsy?

    <p>They have an anorexiant (appetite-suppressing) effect.</p> Signup and view all the answers

    Which of the following is an alternative to stimulant drugs for the treatment of ADHD?

    <p>Atomoxetine</p> Signup and view all the answers

    What is one reason why amphetamines are notorious as street drugs of abuse?

    <p>They have the same therapeutic uses as stimulants approved for ADHD and narcolepsy.</p> Signup and view all the answers

    How do over-the-counter cold medicines containing caffeine affect the stimulant effects of other stimulant drugs?

    <p>They have additive stimulant effects when combined with other stimulant drugs.</p> Signup and view all the answers

    What brain regions make up the reward center stimulated by certain drugs?

    <p>Cerebral cortex, brainstem, reticular activating system</p> Signup and view all the answers

    How are drugs like dextroamphetamine and methylphenidate metabolized in the liver?

    <p>By de-esterification</p> Signup and view all the answers

    What is a common adverse reaction associated with the use of stimulants?

    <p>Insomnia</p> Signup and view all the answers

    Which condition is a contraindication for the use of stimulants?

    <p>Hyperthyroidism</p> Signup and view all the answers

    How does urine acidity affect the excretion of amphetamine?

    <p>Increased alkalinity increases its half-life</p> Signup and view all the answers

    What is a significant drug interaction risk when taking stimulants within 14 days of an MAOI?

    <p>Hypertensive crisis</p> Signup and view all the answers

    What is a precaution regarding the use of Concerta in patients with certain disorders?

    <p>Increased risk of obstructive esophageal disorders</p> Signup and view all the answers

    Which of the following statements about stimulant prescriptions is true?

    <p>States may have mechanisms for providing more than one month's prescription at a time.</p> Signup and view all the answers

    What is the peak duration of action for methylphenidate HCl?

    <p>4-6 hours</p> Signup and view all the answers

    Which of the following is a possible effect when stimulants are taken with MAOIs?

    <p>Increased risk of hypertensive crisis and stroke</p> Signup and view all the answers

    What is the maximum recommended daily dose of dextroamphetamine for children over 5 years old?

    <p>40 mg/day</p> Signup and view all the answers

    Which of the following statements about atomoxetine is true?

    <p>It is primarily excreted through the kidneys.</p> Signup and view all the answers

    What is the recommended starting dose of lisdexamfetamine for a 10-year-old child with ADHD?

    <p>30 mg once daily</p> Signup and view all the answers

    Which of the following statements about the Daytrana patch is false?

    <p>The application site does not need to be rotated.</p> Signup and view all the answers

    According to the drug interactions table, which of the following drugs should be avoided when taking stimulants?

    <p>Tricyclic antidepressants (TCAs)</p> Signup and view all the answers

    What is the recommended maximum daily dose of Ritalin (methylphenidate HCl) for adults?

    <p>60 mg/day</p> Signup and view all the answers

    Which of the following statements about drug interactions with stimulants is false?

    <p>Acidifying agents may increase the effect of stimulants.</p> Signup and view all the answers

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