Podcast
Questions and Answers
What are the components of representative oral contraceptives as mentioned in the text?
What are the components of representative oral contraceptives as mentioned in the text?
- Progestin and Testosterone
- Estrogen and Progestin (correct)
- Estrogen and Testosterone
- Estrogen and Fibrinogen
Which of the following is considered a mild adverse effect of oral contraceptives according to the text?
Which of the following is considered a mild adverse effect of oral contraceptives according to the text?
- Weight Loss
- Increased Blood Coagulability (correct)
- Reduced Amenorrhea
- Decreased Skin Pigmentation
What is a severe adverse effect of oral contraceptives mentioned in the text?
What is a severe adverse effect of oral contraceptives mentioned in the text?
- Increased Skin Pigmentation
- Venous Thromboembolism (VTE) (correct)
- Prolonged Amenorrhea
- Edema
Which type of contraceptives contain estrogen and progestin together?
Which type of contraceptives contain estrogen and progestin together?
What are some common mild adverse effects associated with oral contraceptives?
What are some common mild adverse effects associated with oral contraceptives?
Which adverse effect can be caused by androgenic progestins in oral contraceptives?
Which adverse effect can be caused by androgenic progestins in oral contraceptives?
Which compound reduction can occur due to estrogen-induced effects from oral contraceptives?
Which compound reduction can occur due to estrogen-induced effects from oral contraceptives?
Which risk factor is NOT associated with higher risk of myocardial infarction in women?
Which risk factor is NOT associated with higher risk of myocardial infarction in women?
What effect do high estrogen doses and nonandrogenic progestins have on acne?
What effect do high estrogen doses and nonandrogenic progestins have on acne?
Which phase of the menstrual cycle primarily produces progesterone?
Which phase of the menstrual cycle primarily produces progesterone?
What is the main reason for the rapid metabolic deactivation of progesterone?
What is the main reason for the rapid metabolic deactivation of progesterone?
Which modification enhances progestin potency?
Which modification enhances progestin potency?
Which of the following is NOT a beneficial effect associated with progesterone and progestin drugs?
Which of the following is NOT a beneficial effect associated with progesterone and progestin drugs?
How do progesterone and progestins act as steroid hormone ligands?
How do progesterone and progestins act as steroid hormone ligands?
What is the main reason for the improved oral bioavailability of medroxyprogesterone acetate?
What is the main reason for the improved oral bioavailability of medroxyprogesterone acetate?
Which compound is known for its enhanced potency and metabolic stability?
Which compound is known for its enhanced potency and metabolic stability?
What is the significance of the introduction of D6,7 in megestrol acetate?
What is the significance of the introduction of D6,7 in megestrol acetate?
Which compound was synthesized as an orally available androgen but turned out to be a potent progestin instead?
Which compound was synthesized as an orally available androgen but turned out to be a potent progestin instead?
What is the main reason for the surprising activity of 17a-Ethinyltestosterone as an oral progestin?
What is the main reason for the surprising activity of 17a-Ethinyltestosterone as an oral progestin?
Which compound rapidly deacetylates by first-pass metabolism after oral administration?
Which compound rapidly deacetylates by first-pass metabolism after oral administration?
What effect does the suppression of metabolic hydroxylation/inactivation at C6 have on medroxyprogesterone acetate?
What effect does the suppression of metabolic hydroxylation/inactivation at C6 have on medroxyprogesterone acetate?
What is the primary use of drospirenone?
What is the primary use of drospirenone?
What is the dosage of drospirenone in combined oral contraceptives?
What is the dosage of drospirenone in combined oral contraceptives?
Which of the following is a characteristic of drospirenone?
Which of the following is a characteristic of drospirenone?
Which of the following is a property of drospirenone?
Which of the following is a property of drospirenone?
Which of the following molecules displays a spiro-cyclic structure?
Which of the following molecules displays a spiro-cyclic structure?
Which of the following is a common use of drospirenone?
Which of the following is a common use of drospirenone?
What is the mechanism of action of drospirenone in the kidney?
What is the mechanism of action of drospirenone in the kidney?
What is the role of heat shock protein 70 (HSP70) in androgen activation?
What is the role of heat shock protein 70 (HSP70) in androgen activation?
What is the biological precursor of dihydrotestosterone?
What is the biological precursor of dihydrotestosterone?
Which enzyme is responsible for converting testosterone into dihydrotestosterone?
Which enzyme is responsible for converting testosterone into dihydrotestosterone?
What is the primary drug target in benign prostatic hyperplasia?
What is the primary drug target in benign prostatic hyperplasia?
Which mechanism-based inhibitor of 5α-reductase is specific for type II enzymes?
Which mechanism-based inhibitor of 5α-reductase is specific for type II enzymes?
What is the difference in specificity between finasteride and dutasteride?
What is the difference in specificity between finasteride and dutasteride?
Which drug has a longer elimination half-life, finasteride or dutasteride?
Which drug has a longer elimination half-life, finasteride or dutasteride?
Which condition can be treated with 5α-reductase inhibitors like finasteride and dutasteride?
Which condition can be treated with 5α-reductase inhibitors like finasteride and dutasteride?
Which component of the androgen receptor complex helps to recruit general transcription factors (GTFs) to the androgen-response element?
Which component of the androgen receptor complex helps to recruit general transcription factors (GTFs) to the androgen-response element?
What is the primary location where dihydrotestosterone exerts its physiological effects?
What is the primary location where dihydrotestosterone exerts its physiological effects?
