Stem Cells in Medicine

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18 Questions

What is the primary goal of blocking the self-renewal pathway in stem cells?

To induce differentiation into a specific cell type

Which of the following transcription factors is involved in the induction of pluripotency in stem cells?

Nanog

What is the purpose of using short interference RNA (siRNA) in stem cell therapies?

To inhibit gene expression

How are genes typically transferred into cultured cells for stem cell-based therapies?

Through direct injection into the cell

What is the primary advantage of using stem cell-based therapies for autoimmune disease treatment?

To avoid the need for immunosuppressive therapy

What is the role of OCT-3/4 in stem cell pluripotency?

To induce pluripotency

What is the primary goal of using stem cells in cardiac repair?

To regenerate damaged blood vessels and heart muscle

What technique is used to manipulate the DNA of stem cells?

CRISPR-Cas9

What is a characteristic of pluripotent stem cells?

They can differentiate into any cell type

What is the role of siRNA in stem cell therapy?

To block the transcription of genes involved in disease

What is the goal of using stem cells in autoimmune disease treatment?

To block the autoimmune response

What is the source of stem cells used in some therapeutic approaches?

Human BM stem cells

What happens when Caspase 8 is inhibited?

Necroptosis is promoted

What is the result of glucagon binding to its receptor on liver cells?

Hydrolysis of triacylglycerols is enhanced

What is the role of the inflammasome in the immune response?

To enhance inflammation

How do Ag-Ab complexes contribute to the immune response?

By activating the complement system

What is the result of UNF-kB activation?

Cytokine production is stimulated

What is the purpose of gene manipulation in stem cell therapy?

To enhance stem cell pluripotency

Explore the potential of stem cells in regenerative medicine, including their use in repairing damaged heart muscle and generating new neurons. Learn about the different types of stem cells and their applications in personalized medicine. Discover how stem cells can help treat cardiomyopathy and other diseases.

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