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18 Questions

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Stem Cells in Medicine

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Questions and Answers

What is the primary goal of blocking the self-renewal pathway in stem cells?

To inhibit transcription factor activity

To induce differentiation into a specific cell type (correct)

To promote cell proliferation

To initiate genetic alterations

Which of the following transcription factors is involved in the induction of pluripotency in stem cells?

Stats 3

Nanog (correct)

KLF4

SOX2

What is the purpose of using short interference RNA (siRNA) in stem cell therapies?

To induce gene expression

To inhibit gene expression (correct)

To initiate genetic alterations

To promote cell proliferation

How are genes typically transferred into cultured cells for stem cell-based therapies?

Through direct injection into the cell Signup and view all the answers

What is the primary advantage of using stem cell-based therapies for autoimmune disease treatment?

To avoid the need for immunosuppressive therapy Signup and view all the answers

What is the role of OCT-3/4 in stem cell pluripotency?

To induce pluripotency Signup and view all the answers

What is the primary goal of using stem cells in cardiac repair?

To regenerate damaged blood vessels and heart muscle Signup and view all the answers

What technique is used to manipulate the DNA of stem cells?

CRISPR-Cas9 Signup and view all the answers

What is a characteristic of pluripotent stem cells?

They can differentiate into any cell type Signup and view all the answers

What is the role of siRNA in stem cell therapy?

To block the transcription of genes involved in disease Signup and view all the answers

What is the goal of using stem cells in autoimmune disease treatment?

To block the autoimmune response Signup and view all the answers

What is the source of stem cells used in some therapeutic approaches?

Human BM stem cells Signup and view all the answers

What happens when Caspase 8 is inhibited?

Necroptosis is promoted Signup and view all the answers

What is the result of glucagon binding to its receptor on liver cells?

Hydrolysis of triacylglycerols is enhanced Signup and view all the answers

What is the role of the inflammasome in the immune response?

To enhance inflammation Signup and view all the answers

How do Ag-Ab complexes contribute to the immune response?

By activating the complement system Signup and view all the answers

What is the result of UNF-kB activation?

Cytokine production is stimulated Signup and view all the answers

What is the purpose of gene manipulation in stem cell therapy?

To enhance stem cell pluripotency Signup and view all the answers