Stem Cells: Definition, Classification, and Medical Applications

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What is the main characteristic of stem cells related to cell division?

Continuous cell division

What is the term used to describe the ability of stem cells to differentiate into specialized cells?

Potency

What is the main characteristic of the nucleus of a stem cell?

Mainly euchromatin

What is found in the cytoplasm of a stem cell?

Numerous polyribosomes and mitochondria

Where are stem cells located?

Throughout the body, in various tissues and organs

What is the characteristic of a stem cell niche?

It provides a microenvironment where stem cells are present in an undifferentiated and self-renewable state.

What type of division occurs in the early embryonic life to maintain the stem cell population?

Symmetrical division giving rise to identical daughter stem cells.

What is the main characteristic of pluripotent stem cells?

They differentiate into all derivatives of the three primary germ layers.

Under what conditions do stem cells regularly divide to repair and replace damaged tissues?

Regularly in organs like the gut and bone marrow.

What is the ability of stem cells under certain physiological or experimental conditions?

They can be induced to become specialized cell types.

Study Notes

Stem Cell Characteristics

  • The main characteristic of stem cells related to cell division is their ability to self-renew, meaning they can divide to produce more stem cells.

Stem Cell Differentiation

  • The term used to describe the ability of stem cells to differentiate into specialized cells is potency.

Nucleus of Stem Cells

  • The main characteristic of the nucleus of a stem cell is that it is diploid, containing a complete set of chromosomes.

Cytoplasm of Stem Cells

  • The cytoplasm of a stem cell contains a high concentration of organelles, particularly ribosomes, which are involved in protein synthesis.

Stem Cell Location

  • Stem cells are located in specific regions of the body, such as bone marrow, adipose tissue, and epithelial tissues.

Stem Cell Niche

  • The characteristic of a stem cell niche is that it provides a unique microenvironment that supports stem cell self-renewal and maintenance.

Stem Cell Division

  • In early embryonic life, symmetric division occurs to maintain the stem cell population.

Pluripotent Stem Cells

  • The main characteristic of pluripotent stem cells is that they have the ability to differentiate into all three primary germ layers: ectoderm, endoderm, and mesoderm.

Stem Cell Division in Tissue Repair

  • Under homeostatic conditions, stem cells regularly divide to repair and replace damaged tissues.

Stem Cell Plasticity

  • The ability of stem cells under certain physiological or experimental conditions is known as stem cell plasticity, which allows them to change their differentiation pathway.

This quiz covers the definition, characteristics, classification, sources, similarities and differences, and medical applications of stem cells. It is based on the content from the Histology & Cell Biology department and references the Oxford Handbook of Medical Sciences 2nd edition, chapter 15, pages 938-939.

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