Podcast
Questions and Answers
Which of the following is NOT one of the minimal set of transcription factors required to dedifferentiate an adult cell?
Which of the following is NOT one of the minimal set of transcription factors required to dedifferentiate an adult cell?
- Nanog (correct)
- Oct3/4
- c-myc
- Sox2
Which of the following is an alternative approach for reprogramming cells, compared to using the four transcription factors?
Which of the following is an alternative approach for reprogramming cells, compared to using the four transcription factors?
- Using small molecules
- Using modified-RNA
- Using proteins
- All of the above (correct)
Which of the following is a challenge associated with using induced pluripotent stem cells (iPSCs) compared to embryonic stem cells (ESCs)?
Which of the following is a challenge associated with using induced pluripotent stem cells (iPSCs) compared to embryonic stem cells (ESCs)?
- Tumors associated with c-myc re-expression
- Differentiation potential and variation from colony to colony
- Low efficiency of reprogramming
- All of the above (correct)
Which of the following epigenetic modifications is associated with gene activation?
Which of the following epigenetic modifications is associated with gene activation?
What is the biggest challenge in grafting hESC-derived cardiomyocytes in a model of myocardial ischemia?
What is the biggest challenge in grafting hESC-derived cardiomyocytes in a model of myocardial ischemia?
What is a characteristic of umbilical cord blood stem cells?
What is a characteristic of umbilical cord blood stem cells?
Which statement about adult stem cells is true according to the text?
Which statement about adult stem cells is true according to the text?
What is a unique property of embryonic stem cells compared to adult stem cells?
What is a unique property of embryonic stem cells compared to adult stem cells?
Where is the subventricular zone (SVZ) located?
Where is the subventricular zone (SVZ) located?
What is the main function of cardiac stem cells according to the text?
What is the main function of cardiac stem cells according to the text?
Which of the following is a key challenge in using embryonic stem cells (ESCs) for cell replacement therapies?
Which of the following is a key challenge in using embryonic stem cells (ESCs) for cell replacement therapies?
What is the primary advantage of using adult stem cells, such as hematopoietic stem cells (HSCs), for cell replacement therapies?
What is the primary advantage of using adult stem cells, such as hematopoietic stem cells (HSCs), for cell replacement therapies?
What is the primary function of mesenchymal stem cells (MSCs) in the body?
What is the primary function of mesenchymal stem cells (MSCs) in the body?
Which of the following is an advantage of transdifferentiation over reprogramming to a pluripotent state?
Which of the following is an advantage of transdifferentiation over reprogramming to a pluripotent state?
Which of the following cell types has been successfully generated via transdifferentiation from pancreatic exocrine cells?
Which of the following cell types has been successfully generated via transdifferentiation from pancreatic exocrine cells?
Which of the following is a potential application of research with embryonic stem cells (ESCs)?
Which of the following is a potential application of research with embryonic stem cells (ESCs)?
What combination of factors was used to induce transdifferentiation of cardiac fibroblasts into cardiac myocytes?
What combination of factors was used to induce transdifferentiation of cardiac fibroblasts into cardiac myocytes?
Which of the following cell types has been generated via transdifferentiation from skin fibroblasts?
Which of the following cell types has been generated via transdifferentiation from skin fibroblasts?
Which of the following approaches has been used to induce transdifferentiation of fibroblasts into cardiac myocytes?
Which of the following approaches has been used to induce transdifferentiation of fibroblasts into cardiac myocytes?
