Statistics Definitions

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Questions and Answers

The pre-determined probability of making a Type I error, typically set at 0.05 (5%), is known as the ______.

Alpha Level

[Blank] refers to how well the results of a study apply to a specific patient or clinical setting, influencing treatment decisions.

Applicability

The ______ is calculated by finding the absolute difference in outcome rates between the experimental and control groups, quantifying the intervention's impact.

Absolute Risk Reduction (ARR)

To assess the effect on three or more groups, one should use the statistical test known as ______.

<p>Analysis of Variance (ANOVA)</p> Signup and view all the answers

[Blank] introduces systematic error into a study, potentially leading to an inaccurate estimation of the true effect of a treatment.

<p>Bias</p> Signup and view all the answers

[Blank] is employed to minimize bias by keeping participants, researchers, or data analysts unaware of treatment assignments.

<p>Blinding</p> Signup and view all the answers

The ______ is a method to correct for multiple comparisons, adjusting the significance level to decrease the chance of Type I errors.

<p>Bonferroni Correction</p> Signup and view all the answers

A relationship where one factor directly influences a change in another is defined as ______.

<p>Causation</p> Signup and view all the answers

In single-subject designs, a ______ visually represents trends in data across different phases, showing progress made.

<p>Celeration Line</p> Signup and view all the answers

The ______ is utilized to analyze nominal data by comparing observed frequencies against expected frequencies.

<p>Chi-Square Test</p> Signup and view all the answers

[Blank] assesses if an observed effect is substantial enough to create a tangible difference in patients' lives.

<p>Clinical Meaningfulness</p> Signup and view all the answers

A ______ provides a range of values that likely contains the true population parameter, offering a measure of the estimate's precision.

<p>Confidence Interval (CI)</p> Signup and view all the answers

A ______ can distort the observed relationship between an exposure and an outcome because it is associated with both.

<p>Confounding Variable</p> Signup and view all the answers

[Blank] quantifies the strength and direction of the linear relationship between two variables.

<p>Correlation</p> Signup and view all the answers

[Blank] is used to evaluate the internal consistency reliability of a scale or instrument, verifying its dependability.

<p>Cronbach's Alpha</p> Signup and view all the answers

[Blank] like mean, median, and standard deviation, are used to summarize the characteristics of a dataset.

<p>Descriptive Statistics</p> Signup and view all the answers

[Blank] quantifies the magnitude of a treatment effect or the difference between two groups.

<p>Effect Size</p> Signup and view all the answers

[Blank] refers to the effect of a treatment under ideal, controlled conditions, often seen in research settings.

<p>Efficacy</p> Signup and view all the answers

[Blank] measures the effect of a treatment in real-world clinical practice, showing results in everyday situations.

<p>Effectiveness</p> Signup and view all the answers

The ______ in ANOVA represents the ratio of variance between groups to variance within groups, testing for significant differences.

<p>F Value</p> Signup and view all the answers

The best measurement method or diagnostic test available, with very high validity, is referred to as the ______.

<p>Gold Standard</p> Signup and view all the answers

[Blank] is a statistical procedure to determine whether there is enough evidence in a sample to reject a null hypothesis.

<p>Hypothesis Testing</p> Signup and view all the answers

[Blank] refers to statistical methods used to make generalizations about a population based on sample data.

<p>Inferential Statistics</p> Signup and view all the answers

[Blank] is an analysis strategy in RCTs where all participants are analyzed according to their originally assigned group, regardless of treatment received.

<p>Intention-to-Treat (ITT) Analysis</p> Signup and view all the answers

The degree of agreement between multiple raters scoring the same phenomenon independently is known as ______.

<p>Inter-rater Reliability</p> Signup and view all the answers

Flashcards

Alpha Level

The pre-determined probability of making a Type I error, typically set at 0.05 (5%).

Applicability

The extent to which the results of a study can be applied to a specific patient or clinical setting.

Absolute Risk Reduction (ARR)

The absolute difference in the rate of an outcome between the experimental and control groups.

Analysis of Variance (ANOVA)

A statistical test used to compare the means of three or more groups.

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Bias

A systematic error in the design, conduct, or analysis of a study that can lead to an inaccurate estimate of the true effect.

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Blinding

A process where participants, researchers, or data analysts are unaware of treatment assignment to minimize bias.

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Bonferroni Correction

A method to adjust the significance level for multiple comparisons to reduce Type I errors.

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Causation

A relationship where one variable directly causes a change in another variable.

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Chi-Square Test

A statistical test used to analyze nominal (categorical) data by comparing observed with expected frequencies.

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Clinical Meaningfulness

The practical importance of a research finding; whether an effect is large enough to make a real difference.

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Confidence Interval (CI)

A range of values likely to contain the true population parameter with a certain degree of confidence.

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Confounding Variable

A factor associated with both the exposure/intervention and the outcome, potentially distorting the observed relationship.

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Correlation

Statistical measure describing the strength and direction of the linear relationship between two variables.

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Descriptive Statistics

Numerical summaries used to describe and summarize the characteristics of a dataset.

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Effect Size

A statistical measure that quantifies the magnitude of a treatment effect or the difference between two groups.

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Efficacy

The effect of a treatment under ideal, controlled conditions.

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Effectiveness

The effect of a treatment in real-world clinical practice.

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Gold Standard

A measurement method widely considered the best available, with very high validity.

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Hypothesis Testing

Statistical procedure used to determine whether there is enough evidence to reject a null hypothesis.

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Inferential Statistics

Statistical methods used to make inferences or generalizations about a population based on a sample.

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Intention-to-Treat (ITT) Analysis

Analysis where all participants are analyzed according to their originally assigned group, regardless of treatment received.

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Inter-rater Reliability

The degree of agreement between two or more raters who independently score or measure the same phenomenon.

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Intra-rater Reliability

The degree of consistency of scores or measurements made by the same rater at two or more different time points.

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Mean

The arithmetic average of a set of scores.

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Median

The middle value in a distribution of scores when the scores are arranged in order.

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p-value

The probability of obtaining the observed results (or more extreme results) if the null hypothesis were true.

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Statistical Power

The probability that a statistical test will detect a true effect if one exists.

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Reliability

The consistency and reproducibility of a measurement.

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Validity

The extent to which a measurement tool or study accurately measures what it is intended to measure.

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Type I Error

A false positive conclusion; finding a statistically significant difference when no real difference exists.

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Type II Error

A false negative conclusion; not finding a statistically significant difference when a real difference exists.

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Study Notes

  • Alpha Level: The predetermined threshold (usually 0.05) for the probability of committing a Type I error (false positive).
  • Applicability: The degree to which study results are relevant and useful for a specific patient or clinical context.
  • Absolute Risk Reduction (ARR): The actual difference in the rate of an outcome between the treatment and control groups.
  • Analysis of Variance (ANOVA): A statistical test for comparing the means of three or more groups.
  • Bias: Systematic error in study design, conduct, or analysis leading to an inaccurate estimation of the true effect.
  • Blinding: The process of concealing treatment assignment from participants, researchers, or data analysts to minimize bias.
  • Bonferroni Correction: A method to adjust the significance level in multiple comparisons to reduce the risk of Type I errors.
  • Causation: A relationship where one variable directly influences a change in another.
  • Celeration Line: A line of best fit through data points in a single-subject design, visually demonstrating trends.
  • Chi-Square Test: Used to analyze categorical data by comparing observed and expected frequencies.
  • Clinical Meaningfulness: The practical importance of research findings, indicating a noticeable real-world impact on patients' lives.
  • Confidence Interval (CI): A range of values likely to contain the true population parameter, given a certain confidence level.
  • Confounding Variable: A factor associated with both the exposure and the outcome, potentially distorting the observed relationship.
  • Correlation: A statistical measure describing the strength and direction of the linear association between variables.
  • Cronbach's Alpha: Assesses the internal consistency reliability of a scale or instrument.
  • Descriptive Statistics: Numerical summaries such as mean, median, and standard deviation to describe a dataset's characteristics.
  • Effect Size: Quantifies the magnitude of a treatment effect or the difference between groups.
  • Efficacy: The effect of a treatment under ideal, controlled conditions.
  • Effectiveness: The effect of a treatment in real-world clinical practice.
  • F Value: The test statistic calculated in ANOVA, which is the ratio of variance.
  • Gold Standard: A measurement or diagnostic test considered the best available due to its high validity.
  • Hypothesis Testing: A statistical procedure to determine if there is sufficient evidence to reject the null hypothesis.
  • Inferential Statistics: Methods to make generalizations about a population based on sample data.
  • Intention-to-Treat (ITT) Analysis: In RCTs, all participants are analyzed based on their originally assigned group, regardless of treatment received.
  • Inter-rater Reliability: Agreement between two or more raters scoring or measuring the same thing.
  • Intra-rater Reliability: Consistency of measurements made by the same rater at different times.
  • Kappa (κ): Measures inter-rater or intra-rater reliability for categorical data, accounting for chance agreement.
  • Kendall's Tau (τ): A non-parametric test measuring the ordinal association between two quantities.
  • Likert Scale: An ordered scale measuring attitudes or opinions, with responses ranging from one extreme to another.
  • Mean: The arithmetic average of a dataset.
  • Median: The middle value in an ordered dataset.
  • MeSH (Medical Subject Headings): A controlled vocabulary for indexing articles in PubMed.
  • Minimal Clinically Important Difference (MCID): The smallest change in an outcome considered meaningful by patients.
  • Mode: The most frequent value in a dataset.
  • Nominal Scale: Data categorized into unordered, mutually exclusive categories.
  • Number Needed to Treat (NNT): The number of patients needed to be treated for one to experience a beneficial outcome compared to the control.
  • Ordinal Scale: Data categorized into ordered categories with unequal intervals.
  • p-value: The probability of obtaining the observed results if the null hypothesis is true.
  • Pearson Product-Moment Correlation Coefficient (r): Measures the strength and direction of a linear relationship between two continuous variables.
  • PEDro (Physiotherapy Evidence Database): A database of physiotherapy clinical trials, systematic reviews, and guidelines.
  • Power (Statistical Power): The probability of a test detecting a true effect if one exists.
  • Predictive Validity: The extent to which a measure can predict a future outcome.
  • Psychometric Properties: Qualities of an outcome measure related to its reliability and validity.
  • Range: The difference between the highest and lowest values in a dataset.
  • Rankin Scale (Modified Rankin Scale - mRS): An ordinal scale measuring disability or dependence, common in stroke research.
  • Ratio Scale: Ordered, continuous categories, equal intervals, and a true zero point.
  • Relative Risk Reduction (RRR): The proportional reduction in risk in the treatment group compared to the control group.
  • Reliability: The consistency and reproducibility of a measurement.
  • Repeated Measures ANOVA: Statistical test comparing multiple measurements from the same subjects.
  • Research Notation: A shorthand system used to diagram the design of an intervention study.
  • Sampling: Selecting a subset (sample) from a larger group (population) to study.
  • Sham Group: A control group receiving a placebo or inactive intervention.
  • Single-Subject Design (SSD): A research design that follows one participant intensively over time.
  • Spearman's Rho (ρ): Measures the monotonic relationship between two ordinal or non-normally distributed variables.
  • Standard Deviation (SD): A measure of the spread of data around the mean.
  • Standard Error of Measurement (SEM): Estimate of score variability around a true score.
  • Statistical Significance: Determination of whether results are likely due to a real effect or chance.
  • Stratification: Ensuring important characteristics are evenly distributed across treatment groups in RCTs.
  • Study Power: The probability that a study will detect a statistically significant difference if it exists.
  • T-test: Statistical test to compare the means of two groups.
  • Threat: An uncontrolled factor in a study impacting an outcome.
  • Triangulation: Using multiple data sources or methods to study a phenomenon.
  • Type I Error: A false positive conclusion.
  • Type II Error: A false negative conclusion.
  • Validity: The extent to which a measurement tool accurately measures what it intends to measure.
  • Variance: A measure of data spread.

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