Podcast
Questions and Answers
How can your DNA affect drug response according to the text?
How can your DNA affect drug response according to the text?
- By affecting the targeted drug development process
- By influencing the rate of drug uptake into cells
- By controlling drug metabolism within the body
- By determining the type of drug receptors you have (correct)
In pharmacogenomics, what does the CYP2D6 gene primarily affect?
In pharmacogenomics, what does the CYP2D6 gene primarily affect?
- Drug uptake
- Drug receptors
- Targeted drug development
- Drug metabolism (correct)
How can decreased drug uptake into cells affect drug efficacy?
How can decreased drug uptake into cells affect drug efficacy?
- It causes the drug to accumulate in tissues (correct)
- It enhances targeted drug development
- It increases the drug's effectiveness
- It accelerates the drug's action
What is the role of the SLCO1B1 gene in pharmacogenomics?
What is the role of the SLCO1B1 gene in pharmacogenomics?
How does T-DM1 work in treating HER2-positive breast cancer?
How does T-DM1 work in treating HER2-positive breast cancer?
Which factor can indicate that T-DM1 is not suitable for treating breast cancer?
Which factor can indicate that T-DM1 is not suitable for treating breast cancer?
What happens if drugs are removed from cells too quickly?
What happens if drugs are removed from cells too quickly?
What is the significance of the amount of HER2 in breast cancer treatment with T-DM1?
What is the significance of the amount of HER2 in breast cancer treatment with T-DM1?
What does T-DM1 attach to in breast cancer cells to exert its effects?
What does T-DM1 attach to in breast cancer cells to exert its effects?
What is the impact of taking a smaller dose or changing the drug if amitriptyline is broken down very slowly?
What is the impact of taking a smaller dose or changing the drug if amitriptyline is broken down very slowly?
How do drugs developed based on mutations in genes work?
How do drugs developed based on mutations in genes work?
In pharmacogenomics, drugs created based on mutations in genes will only work for:
In pharmacogenomics, drugs created based on mutations in genes will only work for:
For individuals with cystic fibrosis whose mutations result in a closed channel, how does ivacaftor work?
For individuals with cystic fibrosis whose mutations result in a closed channel, how does ivacaftor work?
Which type of mutation in cystic fibrosis makes ivacaftor ineffective?
Which type of mutation in cystic fibrosis makes ivacaftor ineffective?
What is the main function of the CFTR protein in cystic fibrosis?
What is the main function of the CFTR protein in cystic fibrosis?
How does amitriptyline metabolism relate to drug dosage?
How does amitriptyline metabolism relate to drug dosage?
In pharmacogenomics, how do mutations affect drug responses?
In pharmacogenomics, how do mutations affect drug responses?
What characteristic of gene mutations can determine the effectiveness of drugs based on them?
What characteristic of gene mutations can determine the effectiveness of drugs based on them?
How does ivacaftor act on specific types of CFTR gene mutations in cystic fibrosis?
How does ivacaftor act on specific types of CFTR gene mutations in cystic fibrosis?
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