Podcast
Questions and Answers
What is the first step in the pathogenesis of pulmonary tuberculosis?
What is the first step in the pathogenesis of pulmonary tuberculosis?
- Tubercle bacilli spread through the lymphatics to regional lymph nodes
- Tubercle bacilli are ingested by alveolar macrophages
- Tubercle bacilli multiply intracellularly and form granulomas
- Tubercle bacilli reach the alveoli (correct)
What is the term used to describe an infection that affects multiple organs at the same time?
What is the term used to describe an infection that affects multiple organs at the same time?
- Chronic infection
- Localized infection
- Systemic infection (correct)
- Asymptomatic infection
What is the difference between latent TB and active TB?
What is the difference between latent TB and active TB?
- Latent TB is when the person has no infection, while active TB is when the person has the infection
- Latent TB is when the person has the infection but no disease, while active TB is when the TB bacilli overcome the defense mechanisms and multiply with tissue destruction (correct)
- Latent TB is when the person has a positive tuberculin skin test, while active TB is when the person has a negative test
- Latent TB is when the person has symptoms of the disease, while active TB is when the person has no symptoms
What is the purpose of the tuberculin skin test (Mantoux test)?
What is the purpose of the tuberculin skin test (Mantoux test)?
What is the purpose of including a known positive smear as a positive control in microscopy for tuberculosis diagnosis?
What is the purpose of including a known positive smear as a positive control in microscopy for tuberculosis diagnosis?
How is the result of the tuberculin skin test (Mantoux test) interpreted?
How is the result of the tuberculin skin test (Mantoux test) interpreted?
What does MOTT stand for in the text?
What does MOTT stand for in the text?
Which group of species is known to cause a variety of diseases, especially in children and the immune-suppressed?
Which group of species is known to cause a variety of diseases, especially in children and the immune-suppressed?
Infections by Mycobacterium tuberculosis can occur in different organs due to what factor?
Infections by Mycobacterium tuberculosis can occur in different organs due to what factor?
What percentage of TB cases are HIV-coinfected according to the text?
What percentage of TB cases are HIV-coinfected according to the text?
Why is tuberculosis considered particularly severe in AIDs patients?
Why is tuberculosis considered particularly severe in AIDs patients?
How do tuberculosis infections initially start, according to the text?
How do tuberculosis infections initially start, according to the text?
What is the purpose of using selective enrichment media for the culture of Mycobacteria?
What is the purpose of using selective enrichment media for the culture of Mycobacteria?
What is the purpose of decontaminating specimens before culture?
What is the purpose of decontaminating specimens before culture?
What is the typical appearance of M.tuberculosis colonies on Lowenstein-Jensen agar?
What is the typical appearance of M.tuberculosis colonies on Lowenstein-Jensen agar?
Which of the following is a manual method used for the culture of Mycobacteria?
Which of the following is a manual method used for the culture of Mycobacteria?
What is the purpose of using Kirschner's Broth for the isolation of M.tuberculosis?
What is the purpose of using Kirschner's Broth for the isolation of M.tuberculosis?
What is the importance of a well-prepared and examined smear in the diagnosis of Mycobacterial infections?
What is the importance of a well-prepared and examined smear in the diagnosis of Mycobacterial infections?
What is the purpose of using fluorescent detection in automated culture methods?
What is the purpose of using fluorescent detection in automated culture methods?
Which characteristic is used to categorize Mycobacteria into slow growers and fast growers?
Which characteristic is used to categorize Mycobacteria into slow growers and fast growers?
What is an example of a biochemical test used for identifying Mycobacterium species?
What is an example of a biochemical test used for identifying Mycobacterium species?
What method can differentiate between M. tuberculosis (MTB) and other Mycobacteria?
What method can differentiate between M. tuberculosis (MTB) and other Mycobacteria?
What happens to the BACTEC reading when Mycobacterium tuberculosis (MTB) fails to grow in the presence of NAP in the NAP test?
What happens to the BACTEC reading when Mycobacterium tuberculosis (MTB) fails to grow in the presence of NAP in the NAP test?
Why are specialized antibiotics needed for treating Mycobacterial infections?
Why are specialized antibiotics needed for treating Mycobacterial infections?
Which stain is used as the primary stain in the Ziehl-Neelsen staining technique?
Which stain is used as the primary stain in the Ziehl-Neelsen staining technique?
What is the purpose of the decolorizing step in the Ziehl-Neelsen staining technique?
What is the purpose of the decolorizing step in the Ziehl-Neelsen staining technique?
Which stain is used as the counter-stain in the Auramine staining technique?
Which stain is used as the counter-stain in the Auramine staining technique?
Which disease is caused by the Mycobacterium tuberculosis complex?
Which disease is caused by the Mycobacterium tuberculosis complex?
Which group of mycobacteria is associated with opportunistic infections and low-grade infections?
Which group of mycobacteria is associated with opportunistic infections and low-grade infections?
Which mycobacterial species causes leprosy (Hansen's disease)?
Which mycobacterial species causes leprosy (Hansen's disease)?