Staging of Malignant Disease

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Questions and Answers

What is the main purpose of staging cancer?

To identify the cause of the cancer
To diagnose the type of cancer
To determine the best treatment options for a patient (correct)
To determine the patient's prognosis

What can happen if a patient is overstaged?

Their cancer may spread
Their cancer may be cured
They may receive unnecessary treatment
They may not receive curative treatment (correct)

What is the role of imaging in staging?

To determine the stage of cancer (correct)
To detect metastatic bone disease
To monitor the treatment's effectiveness
To diagnose the type of cancer

Why is microscopic staging not always possible?

It is not possible to biopsy each lesion (A) Signup and view all the answers

What is the accuracy of 18F FDG-PET in staging tumors?

Better than 90% (A) Signup and view all the answers

What is the accuracy of CT in staging mediastinal disease in lung cancer?

Around 70% (A) Signup and view all the answers

What is the primary importance of accurate staging of malignant disease at the time of initial presentation?

To determine the optimal treatment for a particular patient (B) Signup and view all the answers

What is a potential consequence of understaging a patient?

The patient may undergo futile but drastic treatments (A) Signup and view all the answers

What is the advantage of using radiopharmaceuticals in staging neuroendocrine tumors?

They have significant role in staging and follow-up of neuroendocrine tumors (D) Signup and view all the answers

What is the primary limitation of microscopic staging?

It is not always possible to biopsy each and every lesion (A) Signup and view all the answers

What is the approximate accuracy of CT in staging mediastinal disease in lung cancer?

Around 70 % (C) Signup and view all the answers

What is the advantage of 18F FDG-PET in staging tumors?

It has an accuracy of better than 90 % (C) Signup and view all the answers

What is the primary consequence of overstaging a patient?

Denial of curative treatment (D) Signup and view all the answers

Which of the following is a limitation of CT and MRI in staging tumors?

Low accuracy in detecting lymph node involvement (D) Signup and view all the answers

What is the primary advantage of using 18F FDG-PET in staging tumors?

Higher accuracy in detecting lymph node involvement (D) Signup and view all the answers

Why is 99mTc MDP used in staging?

To detect metastatic bone disease (D) Signup and view all the answers

What is the primary role of nuclear medicine procedures in staging?

To provide a more accurate diagnosis compared to CT and MRI (C) Signup and view all the answers

What is the consequence of a patient undergoing futile but drastic treatments?

Increased morbidity and mortality (A) Signup and view all the answers

What is the primary aim of staging malignant disease?

To provide appropriate management for a particular patient (A) Signup and view all the answers

What is the significance of 18F in detecting metastatic bone disease?

It has a higher degree of accuracy in detecting metastatic bone disease (C) Signup and view all the answers

What is the limitation of CT and MRI in staging tumors?

They are less accurate than 18F FDG-PET in staging tumors (A) Signup and view all the answers

What is the primary advantage of using 18F FDG-PET in staging neuroendocrine tumors?

It has a higher degree of accuracy than CT and MRI (B) Signup and view all the answers

What is the consequence of a patient undergoing futile but drastic treatments due to understaging?

Increased morbidity and mortality (D) Signup and view all the answers

Why is 99mTc MDP used in staging?

It is used to detect metastatic bone disease (D) Signup and view all the answers

What is the primary role of nuclear medicine procedures in staging?

To provide accurate staging of tumors (D) Signup and view all the answers

What is the significance of accurate staging of malignant disease at the time of initial presentation?

It helps in providing appropriate management for a particular patient (A) Signup and view all the answers

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Study Notes

Staging of Malignant Disease

Staging of cancer depends on the size of the primary neoplasm, its extent to regional lymph nodes, and the presence or absence of metastasis.
Accurate staging at initial presentation is crucial to provide appropriate management for a patient.

Importance of Accurate Staging

Overstaging can deprive a patient from receiving curative treatment such as surgery.
Understaging can lead to futile treatments, increasing morbidity and mortality without improving the chance of cure.

Role of Imaging in Staging

Imaging plays a significant role in staging, particularly in detecting metastatic bone disease using 99mTc MDP and 18F.
Radiopharmaceuticals are used in staging and follow-up of neuroendocrine tumors.

Accuracy of Imaging Modalities

18F FDG-PET has a higher degree of accuracy (better than 90%) compared to CT (approximately 70%) and MRI (around 80%) in staging tumors, particularly lymph node involvement.