Stability Evaluation through Stress Testing

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What is the primary advantage of semi-solid dosage forms over other routes of administration?

Facilitated drug termination in problematic cases

What is a limitation of semi-solid dosage forms?

Lack of dosage accuracy

What is the primary function of ointments?

To serve as vehicles for the topical application of drug substances

What is a characteristic of hydrophobic ointments?

They are usually anhydrous and can absorb only small amounts of water

What is the purpose of ointments in therapeutic applications?

To protect the skin or mucous membrane

Which type of ointment can absorb large amounts of water?

Water-emulsifying ointments

What is a disadvantage of semi-solid dosage forms?

The base can be easily oxidized

What is the primary difference between hydrophobic and water-emulsifying ointments?

Their ability to absorb water

What is a characteristic of ointments?

They are homogenous and semi-solid

What is the significance of the base used in semi-solid dosage forms?

It can be easily oxidized

This quiz assesses your knowledge of stress testing in the evaluation of drug substance stability. It covers the purpose of stress testing, its dependence on the drug substance and product type, and its role in identifying degradation products and pathways. Test your understanding of this crucial step in drug development.

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