Questions and Answers
What is the generic name for Spiriva?
tiotropium (tye-o-trope-ee-yum) bromide
What is the trade name of tiotropium bromide?
Spiriva
What are the classifications of Spiriva?
The mode of action of spiriva involves blocking ACh at the ______ receptor site.
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What is Spiriva indicated for?
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What are the contraindications for using Spiriva?
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Which of the following are adverse effects of Spiriva? (Select all that apply)
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What is the recommended dosage for Spiriva?
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Study Notes
Drug Information
- Generic Name: tiotropium bromide, pronounced as tye-o-trope-ee-yum.
- Trade Name: Spiriva.
Classification
- Pharmacologic Classification: Anticholinergic.
- Therapeutic Classification: Bronchodilator.
Mode of Action
- Mechanism involves blocking acetylcholine (ACh) at muscarinic receptors.
- Prevents conversion of guanosine triphosphate (GTP) to cyclic guanosine monophosphate (cGMP).
- Reduces bronchial smooth muscle constriction.
Indications
- Primarily used for long-term maintenance treatment of bronchospasm associated with Chronic Obstructive Pulmonary Disease (COPD).
Contraindications
- Hypersensitivity to tiotropium or ipratropium is a major contraindication.
- Caution needed for individuals with known hypersensitivity to atropine or milk proteins.
Adverse Effects
- Possible side effects include glaucoma, paradoxical bronchospasm, tachycardia, and dry mouth.
- Concurrent use with ipratropium is not advised due to the risk of increased anticholinergic effects.
Dosage/Administration
- Administered as dry powder capsules through inhalation.
- Typical dosage is 18 mcg once daily; onset of action is approximately 30 minutes, with effects lasting over 24 hours.
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Description
Test your knowledge on Spiriva with these flashcards. Covering key terms including generic names, trade names, classification, and mode of action, this quiz is ideal for pharmacy students and healthcare professionals. Perfect for quick review or exam preparation.
