Spinal Cord Structure and Function Quiz

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Questions and Answers

At what vertebral level does the spinal cord typically terminate?

  • S1/S2
  • L3/L4
  • T12/L1
  • L1/L2 (correct)

What is the purpose of a lumbar puncture?

  • To inject anesthetics into the epidural space
  • To collect cerebrospinal fluid for diagnostic purposes (correct)
  • To relieve pain in the lower back
  • To insert a catheter for spinal surgery

Where is the epidural space located?

  • Between the dura mater and pia mater
  • Between the arachnoid and pia mater
  • Outside the dura mater (correct)
  • Within the subarachnoid space

Which meningeal layer does the filum terminale extend from?

<p>Pia mater (A)</p> Signup and view all the answers

What characterizes the grey matter at sacral levels?

<p>There is a higher proportion of grey matter and a 'fat butterfly' appearance (C)</p> Signup and view all the answers

What does the lumbar cistern contain?

<p>Cerebrospinal fluid (D)</p> Signup and view all the answers

As one moves from cervical to sacral levels, what change occurs in the white matter?

<p>White matter decreases as fewer long tracts are present (B)</p> Signup and view all the answers

What anatomical feature allows for the anchoring of the spinal cord to the coccyx?

<p>Filum terminale (C)</p> Signup and view all the answers

What type of sensory information does the spinothalamic tract primarily carry?

<p>Pain, temperature, itch, and simple touch (D)</p> Signup and view all the answers

Which pathway is responsible for conscious proprioception?

<p>Dorsal column-medial lemniscus pathway (C)</p> Signup and view all the answers

What is the primary function of the spinocerebellar pathway?

<p>Non-conscious proprioception (B)</p> Signup and view all the answers

Which of the following describes the decussation of the spinothalamic tract?

<p>Axons cross at the level of the spinal cord (C)</p> Signup and view all the answers

Which descending tract is involved in regulating muscle tone and posture?

<p>Non-pyramidal motor pathways (D)</p> Signup and view all the answers

What sensory modalities does the dorsal column pathway transmit?

<p>Discriminative touch and conscious proprioception (A)</p> Signup and view all the answers

Which tract is part of the pyramidal motor pathway?

<p>Anterior corticospinal tract (B)</p> Signup and view all the answers

What type of information does the vestibulospinal tract help to maintain?

<p>Balance and head stability during movement (B)</p> Signup and view all the answers

What is the primary role of the fasciculus gracilis and fasciculus cuneatus in the sensory pathway?

<p>They transmit sensory information from the lower and upper body. (A)</p> Signup and view all the answers

Which pathway is formed by second-order neurons that decussate at the medulla?

<p>Medial Lemniscus pathway (B)</p> Signup and view all the answers

What percentage of upper motor neuron fibers decussate at the medulla-spinal cord junction?

<p>90% (A)</p> Signup and view all the answers

Which lamina of the spinal cord is primarily responsible for processing pain signals?

<p>Lamina I (B)</p> Signup and view all the answers

Where do proprioceptive signals from muscles and joints first synapse in the spinocerebellar pathway?

<p>Nucleus of Clarke (C)</p> Signup and view all the answers

Which lamina is associated with processing mechanoreceptive signals like touch and pressure?

<p>Lamina III-V (D)</p> Signup and view all the answers

How many pairs of spinal nerves are present in humans?

<p>31 pairs (C)</p> Signup and view all the answers

What characterizes the anterior corticospinal tract in relation to upper motor neuron fibers?

<p>It contains fibers that do not decussate and control trunk muscles. (C)</p> Signup and view all the answers

What type of fibers compose spinal nerves?

<p>Both sensory and motor fibers (B)</p> Signup and view all the answers

What is the function of the dorsal root ganglion?

<p>Houses sensory neuron cell bodies (A)</p> Signup and view all the answers

Where do the centrally projecting axons of sensory neurons enter the spinal cord?

<p>Through the dorsal root (C)</p> Signup and view all the answers

Which vertebra is associated with two pairs of spinal nerves?

<p>C1 vertebra (A)</p> Signup and view all the answers

What type of information does the C2 spinal nerve primarily provide?

<p>Sensory input and motor control to scalp and upper neck (D)</p> Signup and view all the answers

What is the outermost layer of the meninges that surrounds the spinal cord?

<p>Dura mater (C)</p> Signup and view all the answers

What connects the vertebral body and vertebral arch?

<p>Pedicle (D)</p> Signup and view all the answers

What is the primary role of dorsal roots in the spinal cord?

<p>Transmit sensory input to the spinal cord (C)</p> Signup and view all the answers

Which part of the spinal cord is primarily involved in processing sensory information?

<p>Dorsal Horn (C)</p> Signup and view all the answers

Where is the sympathetic chain ganglion located?

<p>Part of the peripheral nervous system (A)</p> Signup and view all the answers

What supplies innervation to the anterolateral trunk and limbs?

<p>Ventral (Anterior) Ramus (D)</p> Signup and view all the answers

Which structure contains myelinated axon tracts for signal transmission?

<p>White Matter (D)</p> Signup and view all the answers

Which segment of the spinal cord contains preganglionic sympathetic neurons?

<p>Lateral Horn (B)</p> Signup and view all the answers

What is the cauda equina comprised of after the spinal cord ends at L1?

<p>Sacral and coccygeal nerve roots (D)</p> Signup and view all the answers

Which part of the spinal cord thickens to form the lumbosacral enlargement?

<p>Cervical enlargement (A)</p> Signup and view all the answers

Flashcards

Spinal Nerve Origin

Each segment of the spinal cord gives rise to a pair of spinal nerves.

Number of Spinal Nerves

Humans have 31 pairs of spinal nerves, one pair for each side of the midline.

Spinal Nerve Function

Spinal nerves combine sensory and motor fibers, enabling communication between the central nervous system (CNS) and the body.

Dorsal Root

The dorsal root contains the cell bodies of sensory neurons, which have two axons.

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Peripherally Projecting Axon

The peripherally projecting axon collects sensory information from the body and carries it to the spinal cord.

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Centrally Projecting Axon

The centrally projecting axon carries sensory information from the dorsal root ganglion to the spinal cord.

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Ventral Root

The ventral root carries the axons of motor neurons, which are found in the ventral part of the spinal cord.

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Motor Neuron Function

The ventral root carries motor commands from the spinal cord to skeletal muscles.

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Subarachnoid Space

The space between the pia mater and arachnoid mater, containing cerebrospinal fluid (CSF) and small blood vessels.

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Epidural Space

A space located between the dura mater and the vertebral canal, containing small veins and fat.

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Dorsal Roots (Sensory)

Carry sensory information from the body towards the spinal cord.

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Ventral Roots (Motor)

Carry motor commands from the spinal cord to muscles.

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Sympathetic Chain Ganglia

A chain of ganglia located on either side of the vertebral column, containing cell bodies of sympathetic neurons.

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Dorsal Horn

The area in the grey matter of the spinal cord responsible for processing sensory information.

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Ventral Horn

The area in the grey matter of the spinal cord that houses motor neurons, which control muscle movement.

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Lumbosacral Enlargement

The thickening of the spinal cord in the lumbar region, giving rise to the lumbar and sacral spinal nerves.

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Conus Medullaris

The tapering end of the spinal cord, typically ending around the L1/L2 vertebral level.

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Cauda Equina

A bundle of spinal nerve roots (from L2 to S5 and the coccygeal nerve) that extends down from the conus medullaris through the lumbar cistern.

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Lumbar Cistern

An enlarged subarachnoid space filled with cerebrospinal fluid (CSF), located between vertebral levels L1/L2 and S2/S3.

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Filum Terminale

A thin structure that extends from the pia mater and anchors the spinal cord to the coccyx.

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Lumbar Puncture (Spinal Tap)

A procedure to insert a needle into the subarachnoid space within the lumbar cistern (between L3/L4 or L4/L5 vertebrae) to collect CSF.

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Grey Matter

The butterfly-shaped region of the spinal cord that contains the cell bodies of neurons. It's more prominent in the lumbar and sacral levels.

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White Matter

The outer region of the spinal cord that contains ascending and descending axons. It's more prominent in the cervical levels due to the many tracts.

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Spinothalamic Tract

Carries information about pain, temperature, itch, and light touch from the body to the brain.

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Dorsal Column-Medial Lemniscus Pathway

Transmits information about fine touch and body awareness (conscious proprioception) from the body to the brain.

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Spinocerebellar Pathway

Carries information about body position and movement without conscious awareness, essential for coordination and balance.

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Pyramidal Motor Pathway

Controls voluntary, conscious movements and involves the lateral and anterior corticospinal tracts.

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Non-pyramidal Motor Pathway

Involved in non-conscious muscle control for balance, posture, and reflexes. Examples include reticulospinal and vestibulospinal tracts.

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Spinothalamic Tract: Sensory Input

Neurons in the dorsal root ganglion (DRG) carry pain and temperature signals into the spinal cord.

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Spinothalamic Tract: Interneuron Projection & Decussation

Sensory neurons synapse with interneurons in laminae I or V of the spinal cord, leading to a crossover to the opposite side.

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Spinothalamic Tract: Ascending Pathway & Synapse

The axons ascend through the brainstem and synapse in the ventral posterior thalamic nuclei, which are organized by body region.

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Dorsal Column Pathway

A pathway in the spinal cord that carries sensory information about touch, pressure, and vibration from the body to the brain. It travels ipsilaterally (on the same side) through the dorsal column of the spinal cord.

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Fasciculus Gracilis

A specialized tract within the dorsal column of the spinal cord that carries sensory information from the lower body, including the legs, feet, and trunk.

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Fasciculus Cuneatus

A specialized tract within the dorsal column of the spinal cord that carries sensory information from the upper body, including the arms, hands, and torso.

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Pyramidal Motor Pathway (Corticospinal Tract)

The primary motor pathway that controls voluntary movement of skeletal muscles. It originates from the primary motor cortex and descends to the spinal cord.

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Lateral Corticospinal Tract

The part of the pyramidal motor pathway where 90% of the fibers cross over (decussate) at the medulla-spinal cord junction, allowing the left brain to control the right side of the body and vice versa.

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Anterior Corticospinal Tract

The part of the pyramidal motor pathway where 10% of the fibers do not cross over (decussate), allowing the brain to control trunk muscles directly.

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Lamina I

A region in the grey matter of the spinal cord involved in processing pain signals from nociceptive sensory neurons.

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Study Notes

Spinal Cord Structure and Function

  • The spinal cord is composed of 31 pairs of spinal nerves, located on either side of the midline.
  • Spinal nerves are formed from the fusion of dorsal and ventral roots.
  • Dorsal roots contain sensory neurons, which have two axons. One axon projects to sensory targets (like skin, muscle), while the other enters the spinal cord.
  • Ventral roots contain motor neurons and their axons, which travel to skeletal muscles.
  • Each vertebra is associated with a pair of spinal nerves, with the exception of C1 which has two pairs.

Spinal Cord Roots and Nerves

  • Dorsal roots carry sensory axons into the spinal cord.
  • Ventral roots carry motor axons and sympathetic axons out of the spinal cord.
  • Once a spinal nerve exits the vertebral column, it splits into Dorsal (Posterior) Ramus and Ventral (Anterior) Ramus.
  • Dorsal Ramus innervates the back (skin and intrinsic muscles).
  • Ventral Ramus innervates the anterolateral trunk and limbs.

Spinal Cord Grey and White Matter

  • Grey matter contains neurons and glia. Subdivided into dorsal horn (sensory processing), ventral horn (motor neurons), intermediate zone (interneurons), and lateral horn (preganglionic sympathetic neurons).
  • White matter consists of myelinated axon tracts (for signal transmission).
  • Dorsal rootlets/root carry sensory signals, while ventral rootlets/root carry motor and sympathetic signals. A mixed spinal nerve combines both.

Spinal Cord Enlargements

  • The spinal cord has enlargements in the cervical and lumbar regions, due to the increased amount of nerves innervating the limbs.
  • The cervical enlargement innervates arms and shoulder.
  • The lumbar enlargement innervates legs and lower body.
  • The lower end of the spinal cord is called the conus medullaris, which continues as the filum terminale, anchoring the spinal cord to the coccyx.

Spinal Cord Protection

  • Protected by the bony vertebral column.
  • Surrounded by three protective layers, meninges: dura, arachnoid, and pia mater.
  • The subarachnoid space between the arachnoid and pia mater contains cerebrospinal fluid (CSF).
  • The epidural space, outside the dura, contains adipose tissue and venous plexuses.

Spinal Cord Pathways

  • Ascending tracts (e.g., dorsal column-medial lemniscus) carry sensory information to the brain.
  • Descending tracts (e.g., corticospinal) carry motor commands from the brain to the spinal cord.
  • Specific pathways transmit specific types of sensory information (e.g., pain, temperature, touch, or proprioception).
  • Spinocerebellar pathway carries non-conscious proprioceptive information to the cerebellum for coordinating movement.

Spinal Cord Clinical Significance

  • Spinal cord lesions can affect both somatic and autonomic motor functions.
  • Lesions at different levels of the spinal cord can cause different neurological symptoms and functional impairments. This depends on which nerves and regions are affected.
  • Diagnosis and treatment need to be specific to localization of the lesion, as deficits can be associated with different regions (e.g., cervical, thoracic, lumbar, sacral).

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