Spinal Cord Anatomy and Meninges Review
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Questions and Answers

What does the central canal of the spinal cord contain?

  • Epineurium
  • Nerve fibers
  • Blood vessels
  • Cerebrospinal fluid (CSF) (correct)
  • White matter consists of cell bodies surrounding the central canal.

    False (B)

    List the two main types of matter found in the spinal cord.

    Gray matter and white matter

    The _____ root contains sensory neurons that transmit signals to the spinal cord.

    <p>dorsal</p> Signup and view all the answers

    What is the primary function of the spinal meninges?

    <p>To provide protection and stability (A)</p> Signup and view all the answers

    Match the components of the spinal cord with their functions:

    <p>Dorsal root = Carries sensory information Ventral root = Carries motor information Gray matter = Contains cell bodies White matter = Contains axons</p> Signup and view all the answers

    The dura mater is the innermost layer of the meninges.

    <p>False (B)</p> Signup and view all the answers

    Which of the following structures is located outside the gray matter area?

    <p>White matter (C)</p> Signup and view all the answers

    At what vertebral level does the spinal cord typically end?

    <p>L1-L2</p> Signup and view all the answers

    The ________ layer of the meninges is separated from the pia mater by the subarachnoid space.

    <p>arachnoid mater</p> Signup and view all the answers

    The pia mater is the outermost layer of the spinal cord membranes.

    <p>False (B)</p> Signup and view all the answers

    Match the following layers of the meninges with their descriptions:

    <p>Dura Mater = Tough fibrous outermost layer that stabilizes the spinal cord Arachnoid Mater = Middle layer with cerebrospinal fluid in the subarachnoid space Pia Mater = Deepest layer that is bound to spinal cord tissue Subarachnoid Space = Region where cerebrospinal fluid flows</p> Signup and view all the answers

    What structure is indicated by the posterior median sulcus in the spinal cord?

    <p>A groove located on the posterior side of the spinal cord</p> Signup and view all the answers

    Which layer of the meninges contains blood vessels?

    <p>Pia mater (A)</p> Signup and view all the answers

    The ventral root and dorsal root come together to form the spinal nerve.

    <p>True (A)</p> Signup and view all the answers

    What fluid flows within the subarachnoid space?

    <p>Cerebrospinal fluid</p> Signup and view all the answers

    What are the main components of a neuron?

    <p>Dendrites, soma, axon (D)</p> Signup and view all the answers

    Neuroglia are responsible for processing information in the nervous system.

    <p>False (B)</p> Signup and view all the answers

    What is the function of the axon in a neuron?

    <p>To conduct nerve impulses (action potentials) toward the synaptic terminals.</p> Signup and view all the answers

    The __________ are clusters of rough endoplasmic reticulum and free ribosomes found in neurons.

    <p>Nissl bodies</p> Signup and view all the answers

    Match the neuron types with their characteristics:

    <p>Anaxonic = Have more than two processes, but no true axon Bipolar = Have two processes separated by the soma Pseudounipolar = Have a single elongate process with a branching axon Multipolar = Have a single axon and multiple dendrites</p> Signup and view all the answers

    Which of the following neuronal structures contains the nucleus?

    <p>Soma (C)</p> Signup and view all the answers

    Dendritic spines are responsible for conducting nerve impulses away from the cell body.

    <p>False (B)</p> Signup and view all the answers

    What is the role of terminal boutons in a neuron?

    <p>To affect another neuron or effector organ (muscle or gland).</p> Signup and view all the answers

    A __________ neuron has a single axon and multiple dendrites.

    <p>Multipolar</p> Signup and view all the answers

    Match the neuron types with their respective characteristics:

    <p>Anaxonic = Often found in the brain and retina Bipolar = Common in sensory organs Pseudounipolar = Typical for sensory neurons Multipolar = Most common type in the human body</p> Signup and view all the answers

    What initiates the reflex arc associated with muscle contraction?

    <p>Stretching of muscle (D)</p> Signup and view all the answers

    The sensory neuron is activated only after the motor neuron has been stimulated.

    <p>False (B)</p> Signup and view all the answers

    What is the role of the spinal cord in the reflex arc?

    <p>It processes information received from sensory neurons.</p> Signup and view all the answers

    The __________ reflex is controlled by muscle spindles in the quadriceps muscle group.

    <p>patellar</p> Signup and view all the answers

    Match the following steps to their correct sequence in the reflex arc:

    <p>Stimulus (stretching of muscle) = 1 Activation of sensory neuron = 2 Information processing = 3 Activation of motor neuron = 4 Muscle contraction = 5</p> Signup and view all the answers

    Which of the following best describes an effector in the context of reflex actions?

    <p>Muscle that contracts in response to motor neuron activation (D)</p> Signup and view all the answers

    The activation of motor neurons results in muscle contraction.

    <p>True (A)</p> Signup and view all the answers

    What is the function of muscle spindles in the stretch reflex?

    <p>They detect the stretch of the muscle and activate sensory neurons.</p> Signup and view all the answers

    What is the first step in the pathway of a reflex arc?

    <p>Arrival of stimulus and activation of a receptor (C)</p> Signup and view all the answers

    A reflex arc starts at a peripheral receptor and ends at a sensory receptor.

    <p>False (B)</p> Signup and view all the answers

    What is the term for the neural wiring of a single reflex?

    <p>Reflex Arc</p> Signup and view all the answers

    The __________ is responsible for processing information in the reflex arc.

    <p>CNS</p> Signup and view all the answers

    Match the component of reflexes with its function:

    <p>Sensory receptor = Detects stimulus Motor neuron = Delivers response command CNS = Processes information Effector = Carries out the response</p> Signup and view all the answers

    Which of the following is NOT a step in the reflex arc mechanism?

    <p>Conscious decision making (A)</p> Signup and view all the answers

    All reflex responses are voluntary.

    <p>False (B)</p> Signup and view all the answers

    Describe the role of the dorsal root in a reflex arc.

    <p>The dorsal root carries sensory information to the CNS.</p> Signup and view all the answers

    Which column of the spinal cord contains sensory tracts?

    <p>Posterior white column (C)</p> Signup and view all the answers

    The anterior white column contains descending motor tracts.

    <p>True (A)</p> Signup and view all the answers

    Name one type of information conveyed by the lateral white column.

    <p>Motor tracts or sensory tracts</p> Signup and view all the answers

    The _____ ramus connects to smooth muscles, glands, and visceral organs.

    <p>Gray</p> Signup and view all the answers

    Match the following spinal plexuses with their corresponding spinal nerves:

    <p>Cervical plexus = C1–C5 Brachial plexus = C5–T1 Lumbar plexus = T12–L4 Sacral plexus = L4–S4</p> Signup and view all the answers

    What type of fibers do the dorsal roots contain?

    <p>Sensory fibers (A)</p> Signup and view all the answers

    All spinal nerves are strictly motor in function.

    <p>False (B)</p> Signup and view all the answers

    How many pairs of spinal nerves are there in total?

    <p>31 pairs</p> Signup and view all the answers

    The ____ white column is primarily responsible for conveying motor commands to skeletal muscles.

    <p>Anterior</p> Signup and view all the answers

    Match the tracts with their functions:

    <p>Ascending tracts = Carry sensory information to the brain Descending tracts = Carry motor commands from the brain Visceral motor commands = Innervate internal organs Somatic motor commands = Innervate skeletal muscles</p> Signup and view all the answers

    Which of the following structures does NOT belong to the peripheral distribution of spinal nerves?

    <p>Lateral white column (B)</p> Signup and view all the answers

    The visceral motor commands are mainly associated with skeletal muscle function.

    <p>False (B)</p> Signup and view all the answers

    What type of sensory receptors do the dorsal roots receive information from?

    <p>Interoceptors, exteroceptors, and proprioceptors</p> Signup and view all the answers

    Flashcards

    Neuron Structure

    Neurons consist of a soma (cell body), axon, and dendrites. The axon transmits nerve impulses, and dendrites receive signals from other neurons.

    Neuron Function

    Neurons are responsible for transferring and processing information in the nervous system.

    Dendrites

    Branching extensions of a neuron that receive signals from other neurons or the environment.

    Axon

    A long, slender projection of a neuron that transmits nerve impulses away from the soma.

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    Soma (Cell Body)

    The main part of a neuron, containing the nucleus, organelles, and other structures needed for cell function.

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    Nissl Bodies

    Clusters of Rough Endoplasmic Reticulum (RER) and free ribosomes within the neuron's soma, involved in protein synthesis.

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    Multipolar Neuron

    A neuron with one axon and multiple dendrites.

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    Bipolar Neuron

    A neuron with two processes emanating from the cell body – one axon and one dendrite.

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    Pseudounipolar Neuron

    A neuron where the axon and dendrite are fused, seemingly forming one process from the cell body, but has separate branches.

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    Anaxonic Neuron

    A neuron without a distinct axon, with numerous dendrites.

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    Spinal Cord Length

    The spinal cord extends from the brain to the level of vertebrae L1-L2, despite the fact that it is surrounded by the vertebral column which extends all the way down the back.

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    Spinal Meninges

    Specialized membranes that protect the spinal cord, provide physical stability, and absorb shock.

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    Dura Mater

    The tough, fibrous outermost layer of the meninges that stabilizes the spinal cord within the vertebral canal.

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    Arachnoid Mater

    The middle meningeal layer. It is separated from the pia mater by the subarachnoid space, where cerebrospinal fluid flows.

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    Pia Mater

    The deepest meningeal layer that is firmly bound to the brain tissue and the spinal cord tissue. This layer contains blood vessels.

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    Subarachnoid Space

    The space between the arachnoid mater and pia mater that contains cerebrospinal fluid.

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    What do the ventral root and dorsal root form together?

    The ventral and dorsal roots of the spinal nerves come together to form the spinal nerves.

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    Denticulate Ligaments

    These ligaments help to anchor the spinal cord to the dura mater, preventing it from moving excessively within the vertebral canal.

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    Meninges: Dura, Arachnoid, Pia Mater

    Three protective membranes surrounding the brain and spinal cord. The dura is the outermost, tough layer, followed by the arachnoid, a delicate web-like layer, and the pia mater, the innermost layer that closely adheres to the brain and spinal cord.

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    Central Canal of Spinal Cord

    A narrow, fluid-filled canal running down the center of the spinal cord, containing cerebrospinal fluid (CSF).

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    Gray Matter of Spinal Cord

    The inner region of the spinal cord, containing neuronal cell bodies (somas), dendrites, and synapses.

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    White Matter of Spinal Cord

    The outer region of the spinal cord, consisting mainly of myelinated axons, forming tracts or columns.

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    Dorsal Root Ganglion

    A cluster of sensory neuron cell bodies located outside the spinal cord, connected to the dorsal root.

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    Dorsal Root

    The sensory nerve root entering the spinal cord carrying information from the body to the spinal cord

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    Ventral Root

    The motor nerve root exiting the spinal cord carrying information from the spinal cord to the body (muscles and glands)

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    What is a reflex?

    An immediate, involuntary, and automatic response to a stimulus.

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    What is a reflex arc?

    The neural pathway involved in a reflex response, consisting of sensory receptors, sensory neurons, interneurons, motor neurons, and effectors.

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    What is the first step in a reflex arc?

    Activation of a sensory receptor by a stimulus.

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    What happens after the sensory receptor is activated?

    Information is relayed from the sensory receptor to the central nervous system (CNS) via sensory neurons.

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    What happens within the CNS during a reflex?

    Information is processed by interneurons within the CNS, leading to a decision about the appropriate response.

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    What happens after information processing?

    A motor neuron is activated, sending a signal to the effector.

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    What is an effector?

    A muscle or gland that carries out the reflex response.

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    What is a spinal reflex?

    A reflex that involves the spinal cord as the processing center, bypassing the brain.

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    Stretch Reflex

    An involuntary muscle contraction triggered by stretching a muscle. It helps maintain muscle tone, posture, and balance.

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    Muscle Spindle

    A sensory receptor found within muscles that detects changes in muscle length. It sends signals to the spinal cord to initiate the stretch reflex.

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    Sensory Neuron

    A neuron that carries signals from the muscle spindles to the spinal cord.

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    Spinal Cord Processing

    The spinal cord receives information from the sensory neuron and integrates it to determine the appropriate response.

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    Motor Neuron

    A neuron that carries signals from the spinal cord to the muscle, causing it to contract.

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    Muscle Contraction

    The shortening or tightening of a muscle to counteract the stretch.

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    Patellar Reflex

    A specific example of a stretch reflex, triggered by tapping the patellar tendon below the kneecap.

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    Effector

    The muscle involved in carrying out the stretch response, usually the same muscle that was stretched.

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    White Matter Columns

    Groups of nerve fibers (axons) in the spinal cord organized into columns called funiculi. These columns convey sensory and motor information to and from the brain.

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    Funiculi

    The columns of nerve fibers in the white matter of the spinal cord, named after their location: posterior, anterior, and lateral.

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    Ascending Tracts

    Nerve pathways within the funiculi that carry sensory information from the body to the brain.

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    Descending Tracts

    Nerve pathways within the funiculi that carry motor commands from the brain to the body.

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    Spinal Nerve

    A mixed nerve that connects the spinal cord to the rest of the body, carrying both sensory and motor information.

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    Dorsal Ramus

    A branch of a spinal nerve that innervates the muscles and skin of the back.

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    Ventral Ramus

    A branch of a spinal nerve that innervates the muscles and skin of the body wall and limbs.

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    Sympathetic Ganglia

    Clusters of nerve cell bodies that are part of the sympathetic nervous system, controlling the 'fight or flight' response.

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    White Ramus

    A nerve fiber carrying preganglionic sympathetic fibers to the sympathetic ganglia.

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    Gray Ramus

    A nerve fiber carrying postganglionic sympathetic fibers from the sympathetic ganglia to target organs.

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    Rami Communicantes

    The small branches connecting the spinal nerves to the sympathetic ganglia.

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    Somatic Nervous System

    The part of the peripheral nervous system that controls voluntary movements of skeletal muscles.

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    Visceral Nervous System

    The part of the peripheral nervous system that controls involuntary functions like heart rate and digestion.

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    Study Notes

    Nervous System Overview

    • The nervous system controls and adjusts bodily activities, producing rapid but short-lived responses.
    • The system includes the Central Nervous System (CNS) and the Peripheral Nervous System (PNS).

    Central Nervous System (CNS)

    • The CNS (brain and spinal cord) integrates, processes, and coordinates sensory input with motor output.
    • It's the center for intelligence, memory, learning, and emotions.
    • The CNS processes and coordinates sensory input and motor output.

    Peripheral Nervous System (PNS)

    • The PNS consists of all peripheral nerves and nervous tissue outside the CNS.
    • It delivers sensory information to and carries motor commands from the CNS.
    • The afferent division brings sensory information to the CNS.
    • The efferent division carries motor commands to muscles and glands.

    Overview

    • Information processing within the CNS leads to motor commands passing through the efferent division of PNS.
    • The Somatic and Autonomic Systems are components of the nervous system.
    • The autonomic system (efferent) is further subdivided, into voluntary and involuntary functions.
    • Sensory receptors receive information relayed to the CNS.

    Cellular Organization in Neural Tissue

    • Neurons transmit electrical signals throughout the body.
    • Neurons consist of a soma, axon, and dendrites.
    • Neuroglia support and protect the neurons.

    Neuron Structure

    • Dendrites receive stimuli from other cells or environmental changes.
    • The cell body contains the nucleus, ribosomes, mitochondria, etc.
    • The axon transmits electrical signals.
    • The axon terminal transmits signals.
    • An action potential travels down the axon.

    Nissl Bodies & Chromatophilic Substance

    • Nissl bodies and Chromatophilic substance are clusters of RER and free ribosomes.

    Structural Classification of Neurons

    • Anaxonic neurons have multiple processes, but axons are indistinguishable.
    • Bipolar neurons have two processes separated by the cell body.
    • Pseudounipolar neurons have a single process that elongates.
    • Multipolar neurons have one axon and multiple dendrites.

    Synapses

    • Synapses are intercellular communication sites.
    • There are synapses between neurons, between neurons and muscles (neuromuscular), and between neurons and glands (neuroglandular)
    • Synapses typically, involve a presynaptic cell, neurotransmitters, and a postsynaptic cell.

    Structure of a Synapse

    • Terminal arborization and terminal boutons are part of an axon's structure.
    • Neurotransmitters are released from the axon terminal boutons to affect postsynaptic neurons.
    • The synapse is an important structural feature that affects postsynaptic neurons.
    • A synapse’s structure dictates its functionality.
    • Vesicular Synapse is one type of synapse

    Multiple Synapses

    • Neurons can form multiple synapses.

    Neuronal Circuits

    • Divergence spreads signal to multiple neurons/pools in the CNS.
    • Convergence brings input to a single neuron/pool from multiple sources.
    • Serial processing works in a sequential manner.
    • Parallel processing works in a simultaneous manner.
    • Reverberation enables feedback mechanisms that can be either excitatory or inhibitory.

    Neuroglia Functions

    • They form the framework for neural tissue in the CNS.
    • They support the cellular environment.
    • They perform phagocytosis (immune cells).
    • They can reproduce (mitosis division).

    Neuroglia Cell Types in the CNS

    • Astrocytes
    • Oligodendrocytes
    • Microglia
    • Ependymal cells

    Neuroglia Cell Types in the PNS

    • Satellite cells
    • Schwann cells (neurolemmocytes)

    Classification of Neuroglia

    • Satellite cells and Schwann cells are PNS support glial cells.
    • Oligodendrocytes and Astrocytes are CNS support glial cells.
    • Different kinds of glial cells support neurons in different roles.

    Astrocytes

    • They have many cytoplasmic processes.
    • They control the chemical content of the interstitial environment.
    • They help maintain the blood-brain barrier.
    • They isolate neurons from general circulation.
    • They provide structural framework.
    • They help repair damaged neurons.
    • They guide neurogenesis.

    Blood-Brain Barrier

    • Tight junctions and astrocytes facilitate the blood-brain barrier function.
    • Tight junctions prevent the movement of solutes between endothelial cells.
    • Astrocyte feet secrete paracrines promoting tight junctions.

    Oligodendrocytes

    • Similar to astrocytes in function.
    • They have smaller cell bodies and fewer cytoplasmic processes.
    • They produce Myelin to wrap axons effectively.

    White Matter and Grey Matter

    • White matter contains myelinated axons; grey matter contains neuron bodies, dendrites, and unmyelinated axons.

    Myelination of the CNS (White matter)

    • Myelinated axons are in white matter, unmyelinated are in grey matter
    • Oligodendrocytes myelinate the axons of CNS (brain and spinal cord)
    • White matter and grey matter each have distinct neuron compositions.

    Neuroglia of the PNS

    • Satellite cells regulate matter exchange, while Schwann cells form myelin sheaths.
    • Schwann cells, also called neurolemmocytes, form the myelin sheath surrounding peripheral axons.

    Peripheral Axons & Schwann Cells

    • Every peripheral axon, myelinated or unmyelinated, is covered by Schwann cells (neurolemmocytes).

    Anatomy of a Peripheral Nerve

    • Epineurium surrounds the entire nerve.
    • Perineurium surrounds each fascicle (bundle of axons).
    • Endoneurium surrounds individual axons.

    Spinal Cord

    • The spinal cord conducts nerve impulses to and from the brain.
    • The spinal cord processes sensory information for reflex/motor actions.
    • It's about 45 cm long, passing from the brain to vertebra L1-L2.
    • It has cervical, thoracic, lumbar, sacral, and coccygeal regions.

    Gross Anatomy of the Spinal Cord

    • 31 spinal segments. Each segment has: dorsal root, dorsal root ganglia, ventral root, and spinal nerves.
    • The conus medullaris is the inferior tip of the spinal cord.
    • The cauda equina resembles a horse's tail.

    Spinal Meninges

    • These specialized membranes protect, stabilize, and absorb shock.
    • Continuous with cranial meninges.
    • Denticulate ligaments anchor the spinal cord.
    • Dura mater is the outermost, tough layer.
    • Arachnoid mater lies between dura and pia mater; cerebrospinal fluid flows in the subarachnoid space.
    • Pia mater is the deepest layer, tightly bound to the spinal cord.

    Sectional Anatomy of the Spinal Cord

    • Gray matter consists of the central canal (CSF filled), with neuron cell bodies and glial cells.
    • White matter contains axons organized into tracts (columns) located outside the gray matter.
    • Gray matter is organized into posterior, lateral, and anterior horns, and a gray commissure.
    • White matter contains posterior, lateral, and anterior columns, conveying sensory and motor tracts.

    Features of the Spinal Cord

    • Structures observed in a transverse (cross-section) view of the spinal cord include white matter, gray matter, central canal, anterior median fissure, and posterior median sulcus

    Organization of the Spinal Cord's Gray Matter

    • Neuronal cell bodies are organized into groups (nuclei) within the spinal cord's gray matter; sensory and motor nuclei are important distinctions—sensory nuclei receive information, motor nuclei send information.
    • Gray matter is organized into posterior, lateral, and anterior horns, in a transverse sectional view.
    • A gray commissure connects the anterior horns.

    Organization of the Spinal Cord's White Matter

    • Columns of nerves (funiculi) form the white matter.
    • Posterior, lateral, and anterior white columns exist.
    • Columns contain sensory and motor tracts (ascending and descending, respectively).

    Spinal Cord Sensory Information

    • Sensory information from the back, body wall, and limbs enters through the dorsal root.
    • Information enters sensory receptors and travels through the spinal cord.
    • Interoceptors for visceral organs and exteroceptors for body wall and limbs relay sensory input.
    • Rami communicantes are structures associated with sensory and visceral pathways

    Spinal Nerves

    • 31 pairs of nerves arise from the spinal cord. There are 8 cervical, 12 thoracic, 5 lumbar, and 5 sacral, and 1 coccygeal nerves.

    Reflexes

    • A reflex is an involuntary motor response.
    • The reflex arc is the neural pathway involved in a reflex.
    • A reflex arc starts at a sensory receptor and concludes at a peripheral receptor.
    • Reflex arcs include receptor, sensory neuron, interneuron, motor neuron, and effector regions.

    Pathway of a Reflex Arc

    • The sequence of events begins with sensory receptor activation, followed by sensory information relay to the CNS.
    • The CNS processes this information, triggering motor neuron response.
    • The response is then signaled to effectors.

    Spinal Reflexes (Stretch reflex)

    • A reflex action initiated when a muscle is stretched.
    • The stretch reflex is used for physical adjustments to maintain posture or balance.
    • Sensory neurons, spinal cord processing, and motor neuron activation cause the muscle to contract to return to its original length.

    Steps of a Stretch Reflex

    • Stimulus stretches the muscle.
    • Muscle spindle activation of sensory neurons
    • Sensory neuron information processing in CNS
    • Motor neuron activation occurs
    • Muscle contraction occurs as a response.

    Patellar Reflex

    • The patellar reflex is a stretch reflex involving quadriceps muscle spindles.
    • Striking the patellar tendon stretches the quadriceps muscle spindles, activating sensory neurons.
    • Spinal cord processing activates motor neurons in the quadriceps.
    • Resulting quadriceps contraction produces a reflexive kick.

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