Spinal Cord Anatomy and Disorders
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Questions and Answers

What was the percentage of horses that exhibited adverse reactions following myelography?

  • 34% (correct)
  • 41%
  • 25%
  • 50%
  • Which factor was significantly associated with adverse reactions in horses undergoing myelography?

  • Lower contrast-medium volume
  • Reduced CSF volume
  • Shorter general anesthesia time
  • Higher contrast-medium volume (correct)
  • What type of complications were most common during the myelography procedure?

  • Cardiovascular complications
  • Respiratory issues
  • Adverse neurologic reactions (correct)
  • Nausea and vomiting
  • What was the percentage of horses that required euthanasia due to adverse reactions?

    <p>2%</p> Signup and view all the answers

    What was observed in 11% of horses postmyelography?

    <p>Nonspecific hyperthermia</p> Signup and view all the answers

    What relationship was not identified concerning adverse reactions and premyelography status?

    <p>Relationship between AAR and premyelography neurologic grade</p> Signup and view all the answers

    Which of the following was not associated with attenuating nonspecific hyperthermia according to the study?

    <p>Sedative medications</p> Signup and view all the answers

    Study Notes

    Study on Adverse Reactions in Horses Undergoing Myelography

    • Study aimed to investigate complications related to myelography procedures in horses, focusing on adverse reactions (AAR).
    • Hypothesized that AAR correlates with changes in cerebrospinal fluid (CSF) volume due to CSF removal or contrast material addition.
    • Higher premyelography neurologic grade may lead to increased AAR incidence.
    • Non-specific hyperthermia potentially mitigated by anti-inflammatory and osmotic agents.

    Study Design and Population

    • Multi-institutional, retrospective observational study conducted from 2000 to 2012.
    • Sample consisted of 278 horses across five institutions, with varied participant numbers:
      • Institution A: 87 horses
      • Institution B: 68 horses
      • Institution C: 65 horses
      • Institution D: 46 horses
      • Institution E: 12 horses

    Results Summary

    • AAR observed in 95 out of 278 horses (34% prevalence).
    • AAR linked to extended general anesthesia duration (P = 0.04) and higher volumes of contrast medium (P = 0.04).
    • Euthanasia due to AAR occurred in 5 out of 278 horses (2%).
    • Adverse neurologic reactions were the most significant complications, occurring in 15 out of 278 horses (5%).
    • During intra- and postmyelography, 42 out of 235 horses (18%) experienced adverse neurologic reactions.
    • No significant relationship between AAR and premyelography neurologic grade was established (P = 0.31).
    • Non-specific hyperthermia reported in 25 out of 235 horses (11%), with no linkage to anti-inflammatory or osmotic agent administration (P = 0.30).

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    Description

    This quiz explores various aspects of spinal cord anatomy, including its structure and different disorders. Topics cover diagnosis, inflammatory conditions, parasitic infections, and degenerative diseases. Test your knowledge on large animals and their spinal cord health.

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