Spermatogenesis and Oogenesis Overview

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Questions and Answers

From which structure does the nervous system develop?

  • Endoderm
  • Yolk sac
  • Ectoderm (correct)
  • Mesoderm

What does the endoderm give rise to during embryonic development?

  • Epithelium of the primitive gut (correct)
  • Skin epithelium
  • Muscle tissues
  • Nervous system

How much amniotic fluid is present at 37 weeks of gestation?

  • 30 mL
  • 200 mL
  • 1500 mL
  • 1000 mL (correct)

Which of the following statements about the fetal membranes is correct?

<p>The amnion and chorion are fetal membranes. (B)</p> Signup and view all the answers

What is true about the volume of amniotic fluid during pregnancy?

<p>It increases significantly from 10 weeks to 37 weeks. (D)</p> Signup and view all the answers

When does the fetal period begin during pregnancy?

<p>At the ninth week of pregnancy (B)</p> Signup and view all the answers

Which measurement indicates the age of the embryo using crown-heel length?

<p>From the vertex of the skull to the heel (A)</p> Signup and view all the answers

What prevents the adherence of the embryo to the uterus?

<p>Amniotic fluid (B)</p> Signup and view all the answers

What is the typical duration of pregnancy measured from the onset of the last normal menstrual period?

<p>280 days (C)</p> Signup and view all the answers

At what stage of pregnancy can the sex of the fetus typically be determined by ultrasound?

<p>By the 20th week (D)</p> Signup and view all the answers

What proportion of the crown-rump length (CRL) does the length of the head approximate during the third month of pregnancy?

<p>One-half (C)</p> Signup and view all the answers

What changes occur to the eyes of the fetus during the third month of pregnancy?

<p>They begin to move to the ventral aspect of the face. (C)</p> Signup and view all the answers

What is a characteristic of the lanugo hair found on the fetus?

<p>It is a fine hair that covers the fetus. (B)</p> Signup and view all the answers

What is the minimum body weight of a mature newborn considered healthy at birth?

<p>2500 g (A)</p> Signup and view all the answers

Which statement correctly describes the relationship between the vernix caseosa and the skin of the fetus?

<p>It is present by the end of intrauterine life. (B)</p> Signup and view all the answers

What is the role of primary ossification centers during the 12th week of pregnancy?

<p>They are present in long bones and skull. (B)</p> Signup and view all the answers

What process involves the migration of detached cells from the epiblast along the primitive streak?

<p>Gastrulation (D)</p> Signup and view all the answers

Which statement correctly describes the notochord?

<p>It is critical for the formation of the axial skeleton. (B)</p> Signup and view all the answers

What role does the neurenteric canal play during embryonic development?

<p>It is involved in the formation of the nervous system. (D)</p> Signup and view all the answers

Which of the following accurately describes the oropharyngeal membrane?

<p>It separates the stomodeum from the primitive gut. (B)</p> Signup and view all the answers

What is the function of the cloacal membrane during embryonic development?

<p>To temporarily terminate the hindgut without intervening mesoderm. (B)</p> Signup and view all the answers

What happens upon the rupture of the oropharyngeal membrane?

<p>It establishes a connection between the amniotic cavity and the primitive gut. (B)</p> Signup and view all the answers

Which statement correctly outlines the formation of the allantois?

<p>It later becomes obliterated after serving its function. (B)</p> Signup and view all the answers

Which structure is formed first at the cranial end during notochord development?

<p>Notochord (D)</p> Signup and view all the answers

What is the origin of the epithelium of the urinary bladder?

<p>Mesoderm (C)</p> Signup and view all the answers

Which of the following statements about the primitive gut is correct?

<p>The primitive gut is a blind-ending tube divided into foregut, midgut, and hindgut. (C)</p> Signup and view all the answers

What separates the ectodermally lined primitive oral cavity from the endodermally lined pharynx?

<p>Buccopharyngeal membrane (B)</p> Signup and view all the answers

Which germ layer does the proctodeum, the lower part of the anal canal, originate from?

<p>Ectoderm (D)</p> Signup and view all the answers

Which statement about the cloacal membrane is accurate?

<p>The cloacal membrane consists of ectoderm, mesoderm, and endoderm. (B)</p> Signup and view all the answers

Which locations are involved in hemopoiesis during intrauterine life?

<p>Yolk sac, liver, spleen, and red bone marrow (D)</p> Signup and view all the answers

What happens to the oropharyngeal membrane in relation to the cloacal membrane?

<p>The oropharyngeal membrane breaks down earlier than the cloacal membrane. (D)</p> Signup and view all the answers

Which statement is true regarding the germ layers involved in the development of the hindgut?

<p>The hindgut temporarily terminates at a membrane made of ectoderm and endoderm. (D)</p> Signup and view all the answers

What is the first morphologically identifiable cell during erythropoiesis?

<p>Proerythroblast (B)</p> Signup and view all the answers

What is the role of erythropoietin in erythropoiesis?

<p>It acts as a signal for the development of red blood cells (A)</p> Signup and view all the answers

Which of the following membranes appears during the embryonic disc formation?

<p>Cloacal membrane (B), Oropharyngeal membrane (C)</p> Signup and view all the answers

Which statement correctly describes the diameter of cells during erythropoiesis?

<p>Diameter increases from younger to mature erythrocytes (B)</p> Signup and view all the answers

What is the first identifiable cell in granulopoiesis?

<p>Myeloblast (B)</p> Signup and view all the answers

Which granules are first observed in the promyelocytes during granulopoiesis?

<p>Nonspecific granules (A)</p> Signup and view all the answers

What can pluripotent hemopoietic stem cells (CFU-S) be identified by?

<p>Detecting their specific markers (B)</p> Signup and view all the answers

Which statement about the size and shape of CFU-S is accurate?

<p>CFU-S are similar in shape and size to small lymphocytes (C)</p> Signup and view all the answers

Which statement accurately describes oogenesis?

<p>Oogenesis is the process where primary oocytes are formed along with polar bodies. (B)</p> Signup and view all the answers

Which two statements are true concerning spermatogenesis?

<p>Spermatogenesis begins before birth and involves Type A pale spermatogonia dividing into primary spermatocytes. (B), Spermatogenesis commences at puberty, where Type A dark spermatogonia divide into Type A pale spermatogonia. (D)</p> Signup and view all the answers

Which sequence correctly outlines the stages of spermatogenesis?

<p>Type A dark spermatogonium, Type A pale spermatogonium, Type B spermatogonium, primary spermatocyte, secondary spermatocyte, spermatid. (A)</p> Signup and view all the answers

What is the role of the acrosome during spermiogenesis?

<p>It contains enzymes necessary for fertilization. (D)</p> Signup and view all the answers

During which phase does the nucleus of the sperm cell condense?

<p>Spermiogenesis. (A)</p> Signup and view all the answers

Which of the following statements about primordial germ cells is incorrect?

<p>They are produced in the wall of the uterus. (C)</p> Signup and view all the answers

What marks the beginning of spermatogenesis?

<p>At birth, with Type A dark spermatogonia forming Type A pale spermatogonia. (B)</p> Signup and view all the answers

Which process involves the conversion of spermatids into sperm cells?

<p>Spermiogenesis. (B)</p> Signup and view all the answers

Flashcards

Migration of primordial germ cells

The movement of primordial germ cells from the epiblast to the yolk sac and then to the developing gonads.

Oogenesis

The process of developing mature eggs from primordial germ cells.

Primordial germ cell to Oogonia

The first stage of oogenesis where primordial germ cells transform into specialized cells called oogonia.

Spermatogenesis

The process of developing mature sperm cells from primordial germ cells through a series of cell divisions and transformations.

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Spermiogenesis

The final stage of spermatogenesis where spermatids transform into fully functional sperm cells.

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Types of spermatogonia

The cells that initiate spermatogenesis: Type A dark, Type A pale, and Type B spermatogonia.

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Reduction Division & Cytodifferentiation

The process where the number of chromosomes is reduced, and cells differentiate during gametogenesis.

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Acrosome and its function

The acrosome, located in the head of a sperm cell, contains enzymes that help with fertilization.

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Gastrulation

A process where cells of the epiblast move through the primitive streak and node, creating a new layer between the epiblast and hypoblast.

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Primitive streak

The primitive streak is formed on the surface of the ectoderm, acting as a starting point for gastrulation.

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Notochord

The notochord forms from cells migrating from the primitive node and serves as a basis for the development of the axial skeleton.

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Neurenteric canal

A temporary connection between the yolk sac and amniotic cavity, involved in forming the digestive system.

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Oropharyngeal membrane

The oropharyngeal membrane, which separates the stomodeum (primitive mouth) from the primitive gut, is composed of ectoderm and endoderm.

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Cloacal membrane

The cloacal membrane is a temporary structure that separates the hindgut from the outside, eventually forming the anus.

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Allantois

An outpocketing of the yolk sac that extends into the connecting stalk, later becoming obliterated.

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Buccopharyngeal/Oropharyngeal membrane

The blue color represents the epiblast, viewed from the amniotic cavity side, and the arrow points to the buccopharyngeal/oropharyngeal membrane.

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What does the ectoderm develop into?

The ectoderm is one of the three primary germ layers in an embryo. It develops into the nervous system, the outer layer of skin (epidermis), and other structures like hair, nails, and teeth.

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What does the endoderm develop into?

The endoderm is one of the three primary germ layers in an embryo. It gives rise to the lining of the digestive tract, respiratory system, and other internal organs.

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What is the purpose of the amniotic sac?

The amniotic sac is a fluid-filled sac that surrounds the developing embryo or fetus. It provides a protective cushion, helps regulate temperature, and allows the fetus to move freely.

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What is the fetal period?

The fetal period begins at the 9th week of pregnancy and continues until birth. It is characterized by significant growth and development of the fetus.

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How is the age of an embryo estimated?

The crown-rump length (CRL) is a measurement used to estimate the age of an embryo. It is measured from the top of the head (crown) to the bottom of the buttocks (rump).

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What is amniotic fluid?

The amniotic fluid is a clear, watery fluid that fills the amniotic sac. It helps protect the fetus, regulate temperature, and allows for fetal movement.

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What are the fetal membranes?

The amnion and chorion are two fetal membranes. The amnion encloses the amniotic cavity, while the chorion forms the outer layer and contributes to the placenta.

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What is the yolk sac?

The yolk sac is a small sac located outside the embryo. It is essential for early development but eventually shrinks as the placenta takes over its functions.

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Primitive Gut Development

The primitive gut is a blind-ending tube that forms during embryonic development. It's divided into three segments: the foregut, midgut, and hindgut.

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Epithelium Origin in Primitive Gut

The epithelium of the primitive gut originates from the endoderm, a germ layer that gives rise to internal linings of organs.

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Stomodeum Definition

The stomodeum is the ectodermally lined primitive oral cavity, the initial opening of the mouth.

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Proctodeum Origin

The proctodeum, the lower part of the anal canal, originates from the ectoderm, the germ layer that forms the outer layer of the body.

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Membrane Breakdown Order

The oropharyngeal membrane breaks down before the cloacal membrane. This allows for the connection of the oral cavity to the pharynx and the anal canal to the exterior.

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Cloacal Membrane Appearance

The cloacal membrane appears after the embryo undergoes folding. This folding process is crucial for the formation of the digestive system.

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Pregnancy Duration (Menstrual Period)

The length of pregnancy is calculated as 280 days or 40 weeks from the start of the last menstrual period.

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Pregnancy Duration (Fertilization)

The length of pregnancy is calculated as 266 days or 38 weeks from fertilization.

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Fetal Movements in Pregnancy

By the fifth month of pregnancy, a mother can feel the fetus moving.

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Determining Embryo Age (CHL)

The age of the embryo can be determined by measuring the crown-heel length (CHL), which is the distance from the head's top to the foot's sole.

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Lanugo Hair

The lanugo hair, a fine hair covering the fetus, develops early and is shed before birth.

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Vernix Caseosa

The vernix caseosa, a coating protecting the fetus's skin, develops during pregnancy and is shed before birth.

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Fetal Growth Assessment (BPD)

The biparietal diameter of the skull, measured by ultrasound, is used to assess fetal growth.

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Fetal Sex Determination

The external genitalia of a fetus develop sufficiently by the 20th week to be discernible through ultrasound.

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Hemopoiesis

The process of blood cell formation, starting with pluripotent hematopoietic stem cells and differentiating into various blood cell types.

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Yolk Sac Hemopoiesis

The initial site of hemopoiesis in the developing fetus, starting from the second week of gestation, located in the wall of the yolk sac.

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Hepatic Hemopoiesis

The site of hemopoiesis during the fetal period, taking over from the yolk sac, starting from the third month of gestation, located in the liver.

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Splenic Hemopoiesis

The site of hemopoiesis starting from the fourth month of gestation, located in the spleen, lasting for a short period.

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Bone Marrow Hemopoiesis

The site of hemopoiesis starting from the fifth month of gestation, located in the red bone marrow, becoming the primary site after birth.

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Red Bone Marrow

The primary site of hemopoiesis in adults, located within the cavities of bones.

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Pluripotent Hematopoietic Stem Cells (CFU-S)

Multipotent stem cells found in the bone marrow and peripheral blood, capable of self-renewal and differentiating into all blood cell types.

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Erythropoiesis

The process of erythrocyte (red blood cell) formation, starting with a proerythroblast and progressing through various stages.

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Study Notes

Spermatogenesis and Oogenesis

  • The total number of female germ cells in the ovary is approximately 7 million in the fifth month of prenatal development, decreasing to about 2 million at birth, and to about 400 at puberty. Fewer than 500 oocytes will be ovulated.
  • Spermatogenesis and spermiogenesis, the process of sperm development, takes approx. 74 days, with variations possible.
  • Sperm viability is about 4-5 days.
  • Oocyte viability is about 30-40 hours.
  • Average semen ejaculate volume is about 3 mL, containing 40-100 million sperm per mL.
  • Semen contains prostaglandins and fructose, which supports sperm energy. ATP is also a source of energy for sperm cells.

Gametogenesis

  • Gametogenesis is the process of converting germ cells into gametes (sperm and eggs/oocytes).
  • Primordial germ cells form in the epiblast during embryonic development's second week, then migrate to the yolk sac wall, and ultimately to gonads.
  • Reduction of chromosome numbers and differentiation are part of gametogenesis.
  • The process of spermatogenesis and spermiogenesis takes approximately 74 days with variations possible, and the process of Oogenesis starts before birth and finishes in the process of fertilization.

Oogenesis Details

  • Oogenesis is the formation of female gametes (oocytes).
  • Oogonia (female germ cells) differentiate into primary oocytes.
  • Primary oocytes begin meiosis I during fetal development, but arrest in prophase I.
  • Oogenesis begins before birth, with oocytes stopping in prophase I until puberty.

Spermatogenesis Details

  • Spermatogenesis is the formation of male gametes (sperm).
  • Spermatogonia (male germ cells) undergo mitosis and develop into primary spermatocytes.
  • Spermatogenesis begins at puberty in the formation of primary spermatocytes.

Spermiogenesis Details

  • Spermatids differentiate into sperm cells (spermatozoa), in a process called spermiogenesis.
  • The acrosome, a cap-like structure containing enzymes, forms on the head of the sperm during spermiogenesis.
  • The nucleus condenses and the tail develops in the sperm formation process called spermiogenesis.

Additional Concepts

  • Polyspermy prevention: Cortical granules release enzymes to harden the zona pellucida, preventing polyspermy.
  • Fertilization: Sperm fertilizes the oocyte.
  • Cleavage: Zygote divides to form morula, then blastocyst with inner cell mass (embryoblast) and trophoblast.
  • Gastrulation: Formation of germ layers (ectoderm, mesoderm, and endoderm).
  • Neurulation: Formation of the neural tube from the ectoderm.

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