Spatial Data Collection in Stroke Research

Visium

Factors refer to a group of genes unique to phases.

Macrophage dominance was observed in the D2 phase.

<p>Generic glial signature was observed in the D10 phase.</p> Signup and view all the answers

<p>Re-establishment of normal cortical architecture was observed in the D21 phase.</p> Signup and view all the answers

<p>10x Chromium</p> Signup and view all the answers

<p>Dynamic 'switching' of gene expression across different phases of stroke was demonstrated, with unique groups of genes (Factors) identified for each phase.</p> Signup and view all the answers

<p>Spatially isolated gene expression indicates distinct cell populations and gene expression changes as the injury progresses.</p> Signup and view all the answers

<p>Two distinct localization patterns, proximal and distal, were observed when overlaying data from 10x Chromium with spatial data obtained via Visium in the d10 phase.</p> Signup and view all the answers

<p>The experiments on ACSA2+ cells and ACSA2 cells with stringent criteria revealed distinct gene expression patterns, indicating different cell subtypes or states.</p> Signup and view all the answers

<p>Further exploration of glial cell expression at the single-cell level revealed a more robust astrocyte-like pattern.</p> Signup and view all the answers

<p>The absence of discExisting questions indicates a focus on novel findings and potentially undiscovered aspects of gene expression and cell populations in the context of stroke.</p> Signup and view all the answers