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Questions and Answers
What percentage of the pancreas is responsible for endocrine function?
What percentage of the pancreas is responsible for endocrine function?
Which type of cell in the Islets of Langerhans produces the hormone glucagon?
Which type of cell in the Islets of Langerhans produces the hormone glucagon?
What is the main action of insulin produced by beta cells?
What is the main action of insulin produced by beta cells?
Which artery branch supplies the head and part of the duodenum?
Which artery branch supplies the head and part of the duodenum?
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What is the function of somatostatin produced by delta cells?
What is the function of somatostatin produced by delta cells?
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What is the function of ghrelin produced by epsilon cells?
What is the function of ghrelin produced by epsilon cells?
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Where is the pancreas located in the body?
Where is the pancreas located in the body?
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Which part of the pancreas is more inferior to the body and tail?
Which part of the pancreas is more inferior to the body and tail?
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What is a characteristic of the echotexture of the pancreas?
What is a characteristic of the echotexture of the pancreas?
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What is the usual echogenicity of the pancreas compared to the liver?
What is the usual echogenicity of the pancreas compared to the liver?
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Which tributary of the pancreas is mentioned in the text?
Which tributary of the pancreas is mentioned in the text?
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What happens to the echogenicity of the pancreas with age?
What happens to the echogenicity of the pancreas with age?
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In which region of the body does the pancreas lie?
In which region of the body does the pancreas lie?
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What is the primary function of the exocrine tissue in the pancreas?
What is the primary function of the exocrine tissue in the pancreas?
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What is the name of the main pancreatic duct that collects pancreatic juice?
What is the name of the main pancreatic duct that collects pancreatic juice?
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What is the function of the enzyme amylase in pancreatic juice?
What is the function of the enzyme amylase in pancreatic juice?
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What percentage of the pancreas is composed of exocrine tissue?
What percentage of the pancreas is composed of exocrine tissue?
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What is the function of the hormone glucagon in the pancreas?
What is the function of the hormone glucagon in the pancreas?
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What is the name of the structure that allows pancreatic juice to pass into the duodenum?
What is the name of the structure that allows pancreatic juice to pass into the duodenum?
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What is the function of the enzyme trypsin in pancreatic juice?
What is the function of the enzyme trypsin in pancreatic juice?
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During a pancreatic ultrasound, what is the recommended duration of fasting for the patient?
During a pancreatic ultrasound, what is the recommended duration of fasting for the patient?
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What frequency transducer is typically used for pancreatic ultrasound?
What frequency transducer is typically used for pancreatic ultrasound?
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In which plane is the entire pancreas typically visible?
In which plane is the entire pancreas typically visible?
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What is the primary position used for pancreatic imaging?
What is the primary position used for pancreatic imaging?
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In which direction should the transducer be swept during transverse imaging?
In which direction should the transducer be swept during transverse imaging?
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What is the purpose of imaging the pancreas in both transverse and sagittal planes?
What is the purpose of imaging the pancreas in both transverse and sagittal planes?
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What is the typical length of the adult pancreas?
What is the typical length of the adult pancreas?
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What is the diameter of the head of the pancreas in the anteroposterior direction?
What is the diameter of the head of the pancreas in the anteroposterior direction?
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What is the location of the gastroduodenal artery in relation to the head of the pancreas?
What is the location of the gastroduodenal artery in relation to the head of the pancreas?
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What is the name of the duct that dumps secretions into the duodenum via the major papilla?
What is the name of the duct that dumps secretions into the duodenum via the major papilla?
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What is the typical size of the main pancreatic duct?
What is the typical size of the main pancreatic duct?
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What is the location of the splenic vein in relation to the tail of the pancreas?
What is the location of the splenic vein in relation to the tail of the pancreas?
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What is the landmark that helps to identify the body of the pancreas?
What is the landmark that helps to identify the body of the pancreas?
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What is the appearance of the main pancreatic duct on ultrasound?
What is the appearance of the main pancreatic duct on ultrasound?
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Study Notes
Pancreas Anatomy and Function
- Lies in the midline, in the epigastric region, and composed of exocrine and endocrine tissue (90% exocrine, 10% endocrine)
- Performs two main functions: exocrine and endocrine
Exocrine Function
- Acini cells make up 90% of the pancreas and perform exocrine functions
- Produces pancreatic juice containing:
- Amylase (breaks down carbohydrates)
- Lipase (breaks down fats)
- Trypsin, chymotrypsin, and carboxypeptidase (break down proteins)
- Nucleases (break down nucleic acids)
- Sodium bicarbonate (buffers hydrochloric acid)
Endocrine Function
- Islets of Langerhans consist of alpha, beta, delta, gamma, and epsilon cells, which secrete hormones directly into the bloodstream
- Hormones and their actions:
- Insulin (beta cells): glucose → glycogen
- Glucagon (alpha cells): glycogen → glucose
- Somatostatin (delta cells): inhibits alpha and beta cells
- Pancreatic polypeptide (gamma cells): related to blood sugar regulation
- Ghrelin (epsilon cells): related to blood sugar regulation
Vascularity
- Arterial supply:
- Pancreaticoduodenal artery (branches of gastroduodenal artery) supplies the head and part of the duodenum
- Branches of the splenic artery supply the body and tail
- Venous drainage:
- Tributaries of the superior mesenteric vein (SMV) and splenic vein
Pancreas Structure
- Divided into four regions: head, neck, body, and tail
- Head: more inferior (caudal) to the body and tail, with the uncinate process considered part of the head
- Body: more superficial than the head and tail
- Tail: more superior and posterior to the spleen
Sonographic Parameters of the Pancreas
- Varies widely in echogenicity, texture, shape, and size
- Echogenicity: usually isoechoic or hyperechoic to the liver, increasing with age
- Echotexture: homogenous, can have a mottled appearance
- Size: varies, comparable between sexes, decreasing with age
- Shape: varies in shape, with a smooth or lobulated contour
Landmarks for Identifying the Pancreas
- Head: gastroduodenal artery, common bile duct, and inferior vena cava
- Neck and uncinate process: anterior to the superior mesenteric vein (SMV) and portosplenic confluence
- Body: superior mesenteric artery, splenic vein, and aorta
- Tail: splenic vein lies posterior to the tail, with the splenic artery seen in cross-section
Pancreatic Ducts
- Main pancreatic duct or duct of Wirsung: usually merges with the common bile duct before entering the duodenum at the major papilla
- Accessory duct or duct of Santorini: seen on ultrasound, less than 3 mm in size
- Ducts are anechoic (fluid-filled) and seen as linear structures in the pancreas body
Scanning the Pancreas
- Typical scan: 3.5 to 5 MHz transducer, fasting patient, and imaging in 2 planes (transverse and sagittal)
- Windows used: supine, right anterior oblique, left lateral decubitus, and left coronal
- Transverse images: demonstrate the head, body, and tail, with interrogation and imaging from superior to inferior
- Sagittal images: demonstrate the head, body, and tail separately, with interrogation from the body to the head and back to the body, then to the tail and back to the body
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Description
This quiz covers the basics of pancreas anatomy and function, including sonographic landmarks and normal parameters. It also explores how to scan the pancreas and its appearance. Based on Chapter 14 of Sonography: Introduction to Normal Structure and Function, 5th edition.