Solu-Cortef Overview

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Questions and Answers

What is the generic name for Solu-Cortef?

  • Prednisone
  • Hydrocortisone Sodium Succinate (correct)
  • Methylprednisolone
  • Dexamethasone

What is the classification for Solu-Cortef?

Glucocorticoid

What is one mechanism of action for Solu-Cortef?

Increase blood sugar through gluconeogenesis

What are some indications for Solu-Cortef?

<p>Primary and secondary adrenocortical insufficiency, congenital adrenal hypoplasia</p> Signup and view all the answers

Which of the following are contraindications for Solu-Cortef? (Select all that apply)

<p>Immunosuppression (B), Systemic Infection (C), TB (D)</p> Signup and view all the answers

Which of the following are side effects of Solu-Cortef? (Select all that apply)

<p>Nausea (A), Hypertension (B), Seizure (C)</p> Signup and view all the answers

The dose for adults of Solu-Cortef is ____ mg IV/IM over 30 seconds.

<p>100</p> Signup and view all the answers

The pediatric dose for Solu-Cortef is ____ mg/kg IV/IM over 30 seconds.

<p>2</p> Signup and view all the answers

What notes should be followed when administering Solu-Cortef?

<p>Monitor BGC and ECG, draw labs before administering, consider fluid resuscitation.</p> Signup and view all the answers

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Study Notes

Hydrocortisone Sodium Succinate

  • Generic name for Solu-Cortef, a corticosteroid used to treat various conditions.

Glucocorticoid Classification

  • Solu-Cortef is classified as a glucocorticoid, which is a type of steroid hormone.

Mechanism of Action

  • Increases blood sugar levels via gluconeogenesis.
  • Elevates blood pressure by enhancing vascular sensitivity to epinephrine and norepinephrine.

Indications

  • Prescribed for primary and secondary adrenocortical insufficiency.
  • Effective in treating congenital adrenal hypoplasia.

Contraindications

  • Should not be used in patients with systemic infections, immunosuppression issues, tuberculosis, or in premature infants.

Side Effects

  • Potential serious effects include seizures, hypertension, and arrhythmias.
  • Other side effects may involve nausea and imbalances in potassium and sodium levels, as well as hyperglycemia.

Dosage Information

  • Recommended dosage for adults is 100 mg administered intravenously or intramuscularly over 30 seconds.
  • For pediatric patients, the dosage is 2 mg/kg given IV/IM over 30 seconds.

Monitoring and Precautions

  • Continuous monitoring of blood glucose and ECG is essential during treatment.
  • Labs should be drawn prior to administration, and fluid resuscitation may be necessary.

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