Solid Organ Transplant Overview
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Questions and Answers

What is the primary characteristic of embryonic stem cells?

  • Can develop into any cell type (correct)
  • Only exist in the adult body
  • Can only differentiate into specific tissues
  • Are less versatile than adult stem cells
  • In tumor staging, what does a T stage of '2' indicate?

  • Tumor size greater than 5 cm
  • Tumor has broken through the skin
  • Tumor size between 0-2 cm
  • Tumor size between 2-5 cm (correct)
  • Which of the following is a major characteristic of neutropenic fever in oncology patients?

  • Increased platelet production
  • Improved immunity
  • Low white blood cell count (correct)
  • Reduced risk of infections
  • Which option best describes a primary side effect of chemotherapy?

    <p>It inhibits the division of rapidly dividing cells</p> Signup and view all the answers

    What is the significance of a normal white blood cell count range of 4500-11,000?

    <p>Indicates a healthy immune response</p> Signup and view all the answers

    What is a common characteristic of fatigue related to cancer treatment?

    <p>Affects cognitive function</p> Signup and view all the answers

    Which of the following statements about adult/somatic stem cells is accurate?

    <p>They can only differentiate into specific tissue types</p> Signup and view all the answers

    What does a main side effect of using peripheral blood stem cells include?

    <p>More rapid engraftment</p> Signup and view all the answers

    What type of transplant involves donor tissue being placed in a normal anatomical site?

    <p>Orthotopic transplant</p> Signup and view all the answers

    Which of the following is not a type of anti-rejection drug concerned with preventing rejection of the transplanted organ?

    <p>Antibiotics</p> Signup and view all the answers

    What is the primary concern associated with lymphatic buildup in lymphedema compared to regular edema?

    <p>It has a chronic buildup of lymph</p> Signup and view all the answers

    Which of the following scenarios best illustrates a heterotopic transplant?

    <p>A pancreas is placed in a different location than its normal site</p> Signup and view all the answers

    What is one of the significant complications of ionizing radiation treatment?

    <p>Destruction of all tissue integrity</p> Signup and view all the answers

    In terms of energy, what describes the fractional method of radiation treatment?

    <p>Radiation dose spreads over several sessions</p> Signup and view all the answers

    Which of the following statements about graft-versus-host disease (GVHD) is accurate?

    <p>It involves donor T lymphocytes attacking the host tissue</p> Signup and view all the answers

    Which condition is typically characterized by bone pain and originates from plasma cells in the bone marrow?

    <p>Multiple myeloma</p> Signup and view all the answers

    Study Notes

    Solid Organ Transplant

    • Organ testing for communicable diseases is crucial to prevent transmission of infectious agents such as CMV, VRE, HIV, and Hep B/C.
    • Transplant types
      • Allograft: Tissue from one individual to another of the same species.
      • Autologous: Tissue from the same individual, for example, identical twins.
      • Syngenic: Tissue from genetically identical individuals.
      • Xenogenic: Tissue from a different species.
      • Orthotopic: Donor tissue (as in heart transplant) is placed in the same location as the original tissue.
      • Heterotopic: Donor tissue is placed in a different location from the original tissue.
    • Anti-rejection drugs can cause complications such as rejection, infection, inflammation, and immunosuppression. This commonly results in lymphedema which is not the same as edema as it represents a chronic buildup of lymph.

    Additional Concerns (Cancer, etc.)

    • Cancer Assessment and Treatment
      • Cancer is assessed through physical examination, imaging (like X-rays), and biopsies.
      • Tumour staging involves determining size and location of the primary tumour, as well as spread to lymph nodes.
      • Radiation, and chemotherapeutic drugs are used to target rapidly dividing cells.
      • Chemotherapy can cause side effects like hair loss, nausea, and immune suppression.
    • Adverse Effects of Cancer Treatment
      • Patient fatigue and related complications, lasting years or even months, can be common.
      • Long-term health impacts like chronic pain can hinder quality of life.
      • Increased infection risk during treatment and aftercare.
    • Peripheral Neuropathy
      • Radiation and cancer affect sensory nerves.
      • Symptoms may include decreased pain sensation, reduced nerve conduction, sensory or motor deficits, and impaired balance.
    • Other Health Factors
      • Graft-Versus-Host Disease (GVHD)
      • Heart transplant-related concerns (including recovery times and activities).
      • Effects of radiation on different parts of the body, and different considerations of patients with respect to the effects of ionizing radiation.

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    Description

    This quiz covers essential concepts related to solid organ transplants, including types of grafts, the importance of organ testing for diseases, and the complications from anti-rejection medications. Participants will learn about various transplant methods such as allograft, autologous, and xenogenic, as well as the implications of lymphedema.

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