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Questions and Answers
What is the main purpose of the proliferation phase in wound healing?
What is the main purpose of the proliferation phase in wound healing?
Which of the following cells play a crucial role in both the cleaning and proliferation phases of wound healing?
Which of the following cells play a crucial role in both the cleaning and proliferation phases of wound healing?
In which phase of healing should strengthening exercises primarily focus on isometric strengthening to prevent muscle atrophy?
In which phase of healing should strengthening exercises primarily focus on isometric strengthening to prevent muscle atrophy?
What type of exercise is typically introduced in the Functional phase of healing?
What type of exercise is typically introduced in the Functional phase of healing?
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What is the primary function of fibroblasts in the proliferation phase?
What is the primary function of fibroblasts in the proliferation phase?
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Which of the following types of exercise is typically introduced in the Remodel phase to promote tissue healing?
Which of the following types of exercise is typically introduced in the Remodel phase to promote tissue healing?
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How long after injury does the proliferation phase typically reach its peak?
How long after injury does the proliferation phase typically reach its peak?
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In the Subacute phase of healing, which of the following can be used to influence chemical mediators?
In the Subacute phase of healing, which of the following can be used to influence chemical mediators?
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What is the role of the hyaluronic acid and proteoglycans released during the inflammatory phase of wound healing?
What is the role of the hyaluronic acid and proteoglycans released during the inflammatory phase of wound healing?
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Which of the following is NOT a consequence of swelling in the inflammatory phase?
Which of the following is NOT a consequence of swelling in the inflammatory phase?
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Which of the following is a key focus in the Return to Competition phase of healing?
Which of the following is a key focus in the Return to Competition phase of healing?
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What is the main reason why pus formation delays the healing process?
What is the main reason why pus formation delays the healing process?
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What type of exercise is typically introduced in the Functional phase to improve tissue function?
What type of exercise is typically introduced in the Functional phase to improve tissue function?
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What type of exercise is typically introduced in the Subacute phase to improve tissue function?
What type of exercise is typically introduced in the Subacute phase to improve tissue function?
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Which of the following is a characteristic of the subacute phase of inflammation?
Which of the following is a characteristic of the subacute phase of inflammation?
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What is the main aim of the remodeling phase in tissue healing?
What is the main aim of the remodeling phase in tissue healing?
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Which type of collagen is primarily produced during the proliferation phase of tissue healing?
Which type of collagen is primarily produced during the proliferation phase of tissue healing?
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What is the role of mechanical stress in the remodeling phase of tissue healing?
What is the role of mechanical stress in the remodeling phase of tissue healing?
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Which of the following factors can delay the healing process?
Which of the following factors can delay the healing process?
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What is the rationale behind avoiding the use of anti-inflammatory medications and ice in the acute phase of tissue healing?
What is the rationale behind avoiding the use of anti-inflammatory medications and ice in the acute phase of tissue healing?
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Which of the following therapy approaches is recommended for the acute phase of tissue healing?
Which of the following therapy approaches is recommended for the acute phase of tissue healing?
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Why is it important to avoid excessive movement during the healing process?
Why is it important to avoid excessive movement during the healing process?
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What is the typical length of time during which the most significant changes occur in the remodeling phase of tissue healing?
What is the typical length of time during which the most significant changes occur in the remodeling phase of tissue healing?
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What is the primary goal of the bleeding phase in soft tissue healing?
What is the primary goal of the bleeding phase in soft tissue healing?
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Which of these events is NOT a direct result of histamine release during the inflammatory phase?
Which of these events is NOT a direct result of histamine release during the inflammatory phase?
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The five cardinal signs of inflammation are primarily caused by:
The five cardinal signs of inflammation are primarily caused by:
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Which of these is NOT a factor influencing the duration of the bleeding phase?
Which of these is NOT a factor influencing the duration of the bleeding phase?
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What is the role of fibrin in the bleeding phase?
What is the role of fibrin in the bleeding phase?
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During the inflammatory phase, why does redness occur at the injury site?
During the inflammatory phase, why does redness occur at the injury site?
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What is the primary function of the inflammatory phase?
What is the primary function of the inflammatory phase?
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How does the body achieve vasoconstriction during the bleeding phase?
How does the body achieve vasoconstriction during the bleeding phase?
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Flashcards
Swelling
Swelling
The accumulation of fluid in interstitial tissue space due to injury, leading to increased pressure.
Fibrinogen
Fibrinogen
A protein that forms a net to trap debris and particles during inflammation.
Prostaglandins
Prostaglandins
Chemicals released from injured cells that cause pain.
Acute inflammation
Acute inflammation
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Subacute inflammation
Subacute inflammation
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Chronic inflammation
Chronic inflammation
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Proliferation phase
Proliferation phase
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Fibroplasia
Fibroplasia
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Soft Tissue Healing
Soft Tissue Healing
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Phases of Healing
Phases of Healing
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Bleeding Phase
Bleeding Phase
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Homeostasis Phase
Homeostasis Phase
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Inflammation Phase
Inflammation Phase
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Cardinal Signs of Inflammation
Cardinal Signs of Inflammation
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Histamine Role in Healing
Histamine Role in Healing
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Vasodilation
Vasodilation
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Anastomoses
Anastomoses
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Collagen Type III
Collagen Type III
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Maturation Phase
Maturation Phase
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Tensile Strength
Tensile Strength
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Healing Timeline
Healing Timeline
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Factors Delaying Healing
Factors Delaying Healing
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Acute Phase
Acute Phase
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Importance of Inflammation
Importance of Inflammation
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Pain-free ROM
Pain-free ROM
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Isometric strengthening
Isometric strengthening
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Proprioceptive exercises
Proprioceptive exercises
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Subacute phase
Subacute phase
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Remodeling phase
Remodeling phase
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Functional phase
Functional phase
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Neuromuscular coordination
Neuromuscular coordination
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Pharmacotherapy
Pharmacotherapy
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Study Notes
Soft Tissue Healing
- Body adapts to progressive loading; too much or too soon leads to injury.
- Soft tissue healing replaces damaged tissue with living tissue.
- Understanding the healing process is crucial for effective therapy and exercise.
- Healing stages overlap considerably.
- Timeline depends on injury severity, tissue type, and individual factors.
- Healing is divided into four phases: bleeding, inflammation, proliferation, and remodeling.
Bleeding Phase (Homeostasis)
- Aim: Stop bleeding.
- Duration: Few minutes to hours, depending on injury.
- Process:
- Vasoconstriction (blood vessel narrowing) for several seconds to 10 minutes.
- Platelet activation triggers clot formation to prevent excessive bleeding.
- Thrombin converts fibrinogen to fibrin, stabilizing the clot.
Inflammatory Phase
- Aim: Clean the wound, prepare for new tissue growth.
- Necessary for healing.
- Occurs rapidly (6-8 hours post-injury), peaking in 1-3 days and resolving within a few weeks (usually around two weeks).
- Five cardinal signs of inflammation: pain (calor), localized heat (dolor), redness (rubor), swelling (tumor), and loss of function (function laesa).
- Process:
- Injured cells release histamine, causing vasodilation (blood vessel widening, leading to increased blood flow, heat, and redness).
- Increased blood flow delivers oxygen and nutrients, removes waste products.
- Macrophages clean debris.
- Subphases:
- Acute (3-4 days): peak inflammation, vascular and cellular response
- Subacute (10-14 days): phagocytosis (cell eating), specific immune response (B & T cells)
- Chronic (more than a month): continued inflammation, if infection or cleaning was insufficient
Proliferation Phase
- Aim: Grow new tissue (scar tissue) to fill and cover the wound.
- Starts 24-48 hours post-injury and peaks 2-3 weeks later.
- Two processes involved: fibroplasia (fibroblast migration and proliferation), angiogenesis (blood vessel growth).
- Macrophages release chemicals to activate fibroblasts, which migrate to the damaged area and proliferate.
- Fibroblasts are also responsible for wound contraction.
Remodeling Phase
- Aim: Create organized scar tissue that mimics original tissue.
- Begins 2-3 weeks post-injury, though some studies indicate it begins 1 week after.
- Characterized by collagen remodelling.
- Collagen type III (weakened) is replaced by type I (stronger) collagen with an increased structure.
- Final scar strength is typically 80% of original tissue strength.
Factors that Delay Healing
- General: Age, protein deficiency, low vitamin C levels, steroids, NSAIDs, temperature.
- Local: poor blood supply, adhesion to other tissues, prolonged inflammation, excessive movement, or mechanical stress.
Therapy
- Support normal healing; avoid accelerating it.
- Acute Phase (bleeding and inflammation, 1-7 days): Protect from increased blood flow (avoid electrotherapy, heat, and ultrasound); keep area elevated and compressed.
- Subacute Phase: Allow pain-free range of motion, isometric exercises to prevent muscle atrophy; consider additional therapies (electrotherapy, ultrasound).
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Description
Explore the stages of soft tissue healing, including the bleeding and inflammatory phases. Understand how the body adapts and the importance of this process for effective therapy and rehabilitation. This quiz covers the key concepts and timeline of healing phases critical for healthcare professionals.