Sodium-Potassium Pump Mechanism

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Questions and Answers

What ions does the sodium-potassium pump move into and out of the cell?

  • Sodium ions in and potassium ions out
  • Sodium ions only
  • Potassium ions only
  • Sodium ions out and potassium ions in (correct)

What is the role of ATP in the function of the sodium-potassium pump?

  • To stabilize the pump's binding sites
  • To create sodium concentration outside the cell
  • To facilitate the diffusion of potassium ions
  • To provide energy for the pump to move ions against their gradient (correct)

What happens during ATP hydrolysis in the operation of the sodium-potassium pump?

  • Potassium ions are released into the cytoplasm
  • The protein changes shape to face outside (correct)
  • The pump binds more sodium ions
  • The pump stops functioning

What is the effect of the sodium-potassium pump on charge distribution across the cell membrane?

<p>Creates a negative charge inside and a positive charge outside (B)</p> Signup and view all the answers

How many sodium ions are transported outside and potassium ions transported inside by the sodium-potassium pump during one cycle?

<p>Three sodium and two potassium (C)</p> Signup and view all the answers

What is the concentration of sodium outside the cell compared to inside?

<p>Low inside, high outside (B)</p> Signup and view all the answers

What characterizes the sodium-potassium pump as an active transport mechanism?

<p>It requires ATP to move ions against their concentration gradients (B)</p> Signup and view all the answers

Which process is NOT a function of the sodium-potassium pump?

<p>Facilitating passive diffusion of glucose (D)</p> Signup and view all the answers

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Study Notes

Sodium-Potassium Pump

  • The sodium-potassium pump is a protein that moves sodium and potassium ions across the cell membrane.
  • It is an active transporter, meaning it requires energy to function, provided by the breakdown of ATP.
  • Mechanism:
    • The pump binds three sodium ions inside the cell.
    • ATP is hydrolyzed, releasing energy that changes the shape of the protein and causes it to face outwards.
    • Sodium ions are released outside.
    • Two potassium ions bind to the protein on the outside.
    • The protein changes shape again, facing inwards, and releases potassium ions inside the cell.
  • Key characteristics:
    • Moves ions against their concentration gradient: sodium is moved from a low concentration inside to a high concentration outside, while potassium moves from a high concentration outside to a low concentration inside.
    • Requires ATP hydrolysis for energy.
    • Creates concentration and electrical gradients across the cell membrane, which contribute to nerve impulse transmission and muscle contractions.
  • Important for cell functioning:
    • Maintains resting membrane potential, which is crucial for nerve impulse transmission and muscle contractions.
  • ** Concentrations:**
    • Inside the cell: Sodium ~10 meq/L, Potassium ~142 meq/L
    • Outside the cell: Sodium ~142 meq/L, potassium ~10 meq/L

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