15 Questions
Which type of bacteria is Sodium fusidate active against?
Gram-positive bacteria
What is the mechanism of action of Sodium fusidate?
It inhibits bacterial protein synthesis
What are the indications for Sodium fusidate?
Serious Staphylococcal skin infections
What adverse effects are commonly associated with Sodium fusidate?
Nausea, diarrhea, and epigastric discomfort
What precautions should be taken when using Sodium fusidate with statins?
Statins may need to be stopped
Which part of the bacterial cell does Aminoglycosides bind to?
Cell membrane
How do Aminoglycosides enter the bacterial cell?
Active transport across the cell membrane
Which of the following is NOT a factor that can block the energy-dependent rate-limiting step of Aminoglycoside uptake?
Anaerobic conditions
How do Aminoglycosides interfere with protein synthesis?
By blocking initiation of protein synthesis
What is the mechanism of action of Aminoglycosides?
Inhibition of protein synthesis
Which of the following best describes the structure of aminoglycosides?
Two or more amino sugars joined in glycosidic linkage to a hexose nucleus
How do aminoglycosides inhibit protein synthesis?
All of the above
Which of the following is NOT a step in the uptake of aminoglycosides?
Binding to the 30S ribosomal subunit
Which of the following can block the energy-dependent rate-limiting step of aminoglycoside uptake?
Divalent cations (Ca2+ and Mg2+)
How do aminoglycosides interfere with protein synthesis?
All of the above
Test your knowledge on the indications, mechanism of action, and usage of Sodium Fusidate. Learn about its effectiveness against Staphylococcal skin infections, including MRSA, and why it should be avoided topically. Explore its bactericidal mechanism and its impact on bacterial protein synthesis. Discover the range of bacteria that Sodium Fusidate is active against.
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