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Sodium Fusidate

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Questions and Answers

Which type of bacteria is Sodium fusidate active against?

Gram-negative bacteria

Both Gram-positive and Gram-negative bacteria

Neither Gram-positive nor Gram-negative bacteria

Gram-positive bacteria (correct)

What is the mechanism of action of Sodium fusidate?

It inhibits bacterial protein synthesis (correct)

It promotes microbial resistance

It prevents bacterial cell wall synthesis

It disrupts bacterial cell membranes

What are the indications for Sodium fusidate?

Serious Gram-negative bacterial infections

Serious Staphylococcal skin infections (correct)

Serious viral infections

Serious fungal infections

What adverse effects are commonly associated with Sodium fusidate?

Nausea, diarrhea, and epigastric discomfort Signup and view all the answers

What precautions should be taken when using Sodium fusidate with statins?

Statins may need to be stopped Signup and view all the answers

Which part of the bacterial cell does Aminoglycosides bind to?

Cell membrane Signup and view all the answers

How do Aminoglycosides enter the bacterial cell?

Active transport across the cell membrane Signup and view all the answers

Which of the following is NOT a factor that can block the energy-dependent rate-limiting step of Aminoglycoside uptake?

Anaerobic conditions Signup and view all the answers

How do Aminoglycosides interfere with protein synthesis?

By blocking initiation of protein synthesis Signup and view all the answers

What is the mechanism of action of Aminoglycosides?

Inhibition of protein synthesis Signup and view all the answers

Which of the following best describes the structure of aminoglycosides?

Two or more amino sugars joined in glycosidic linkage to a hexose nucleus Signup and view all the answers

How do aminoglycosides inhibit protein synthesis?

All of the above Signup and view all the answers

Which of the following is NOT a step in the uptake of aminoglycosides?

Binding to the 30S ribosomal subunit Signup and view all the answers

Which of the following can block the energy-dependent rate-limiting step of aminoglycoside uptake?

Divalent cations (Ca2+ and Mg2+) Signup and view all the answers

How do aminoglycosides interfere with protein synthesis?