Sodium Fusidate

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Questions and Answers

Which type of bacteria is Sodium fusidate active against?

  • Gram-negative bacteria
  • Both Gram-positive and Gram-negative bacteria
  • Neither Gram-positive nor Gram-negative bacteria
  • Gram-positive bacteria (correct)

What is the mechanism of action of Sodium fusidate?

  • It inhibits bacterial protein synthesis (correct)
  • It promotes microbial resistance
  • It prevents bacterial cell wall synthesis
  • It disrupts bacterial cell membranes

What are the indications for Sodium fusidate?

  • Serious Gram-negative bacterial infections
  • Serious Staphylococcal skin infections (correct)
  • Serious viral infections
  • Serious fungal infections

What adverse effects are commonly associated with Sodium fusidate?

<p>Nausea, diarrhea, and epigastric discomfort (B)</p> Signup and view all the answers

What precautions should be taken when using Sodium fusidate with statins?

<p>Statins may need to be stopped (D)</p> Signup and view all the answers

Which part of the bacterial cell does Aminoglycosides bind to?

<p>Cell membrane (C)</p> Signup and view all the answers

How do Aminoglycosides enter the bacterial cell?

<p>Active transport across the cell membrane (B)</p> Signup and view all the answers

Which of the following is NOT a factor that can block the energy-dependent rate-limiting step of Aminoglycoside uptake?

<p>Anaerobic conditions (D)</p> Signup and view all the answers

How do Aminoglycosides interfere with protein synthesis?

<p>By blocking initiation of protein synthesis (B)</p> Signup and view all the answers

What is the mechanism of action of Aminoglycosides?

<p>Inhibition of protein synthesis (D)</p> Signup and view all the answers

Which of the following best describes the structure of aminoglycosides?

<p>Two or more amino sugars joined in glycosidic linkage to a hexose nucleus (A)</p> Signup and view all the answers

How do aminoglycosides inhibit protein synthesis?

<p>All of the above (D)</p> Signup and view all the answers

Which of the following is NOT a step in the uptake of aminoglycosides?

<p>Binding to the 30S ribosomal subunit (D)</p> Signup and view all the answers

Which of the following can block the energy-dependent rate-limiting step of aminoglycoside uptake?

<p>Divalent cations (Ca2+ and Mg2+) (A)</p> Signup and view all the answers

How do aminoglycosides interfere with protein synthesis?

<p>All of the above (D)</p> Signup and view all the answers

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