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Questions and Answers
What is the role of Acetylcholinesterase (AChE) in neuromuscular transmission?
What occurs when the t-tubules are depolarized?
Where does coupling of electrical activity and calcium release for muscle contraction occur?
What happens when the action potential propagates to the triads?
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Which component is responsible for converting electrical signals into chemical signals at the triads?
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What is the final step in the Power Stroke in Skeletal Muscle and Rigor cycle?
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What is the first step in the sequence of events at the neuromuscular junction for skeletal muscle contraction?
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What occurs when calcium binds to the myofibrils during skeletal muscle contraction?
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What happens when the EPP spreads across the muscle fiber at the neuromuscular junction?
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What is the role of nicotinic receptors at the motor-end plate in the neuromuscular junction?
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What is the role of calmodulin in smooth muscle contraction?
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How does calcium enter the cytoplasm in smooth muscle?
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Which neurotransmitters are involved in activating GPCR pathways in the autonomic nervous system?
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What is the main function of myosin light chain kinase (MLCK) in smooth muscle contraction?
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What role does Ca2+-CaM play in smooth muscle contraction?
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What role does Myosin light chain phosphatase (MLCP) play in smooth muscle relaxation?
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Why does smooth muscle have the ability to prolong muscle contraction without using large amounts of ATP?
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What characteristic of the latch state allows smooth muscle to maintain tone with minimal ATP use?
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How does the latch state contribute to the prolonged tension in smooth muscle?
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Why does maximal velocity directly depend on cross-bridge phosphorylation in smooth muscle?
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What mechanism allows smooth muscle to maintain force for long periods without extensive energy utilization?
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Why does the heart operate at sarcomere lengths lower than the optimal?
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Where is smooth muscle located in the body?
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What is a characteristic of single-unit smooth muscle?
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How do thick filaments in smooth muscle differ from skeletal muscle?
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What is pharmacomechanical coupling in smooth muscle contraction?
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Why do some smooth muscles not require an action potential for contraction?
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