Podcast
Questions and Answers
What is the primary role of the cohesin proteins in eukaryotic cells?
What is the primary role of the cohesin proteins in eukaryotic cells?
- To regulate the ON and STOP switches for cell division
- To link together sister chromatids after replication and keep them together during chromosome condensation (correct)
- To maintain the condensed structure of chromosomes during mitosis
- To induce positive supercoiling in DNA during chromosome condensation
How do the condensin proteins affect the structure of DNA when they bind to it?
How do the condensin proteins affect the structure of DNA when they bind to it?
- They cause the DNA to become underwound
- They have no effect on the DNA's supercoiling
- They create positive supercoils in the DNA, causing it to become overwound (correct)
- They induce negative supercoiling in the DNA
Which of the following is NOT a key transition point in the eukaryotic cell cycle?
Which of the following is NOT a key transition point in the eukaryotic cell cycle?
- The point where sister chromatids are segregated during cell division
- The point where chromosomes condense as cells enter mitosis (correct)
- The ON switch, where a cut or break in tissue causes cells to grow rapidly
- The STOP switch, where cells stop growing when they bump into each other
Which of the following statements about SMC proteins is true?
Which of the following statements about SMC proteins is true?
What is the main function of the condensin proteins in eukaryotic cells?
What is the main function of the condensin proteins in eukaryotic cells?
Which of the following cell types are most likely to rarely or never divide?
Which of the following cell types are most likely to rarely or never divide?
What are the red bars indicating in the eukaryotic cell cycle?
What are the red bars indicating in the eukaryotic cell cycle?
What are cyclins in relation to the cell cycle regulation?
What are cyclins in relation to the cell cycle regulation?
What are internal regulators in the cell cycle control process?
What are internal regulators in the cell cycle control process?
What is the consequence of uncontrolled cell growth as mentioned in the text?
What is the consequence of uncontrolled cell growth as mentioned in the text?
What is a characteristic of a benign tumor mentioned in the text?
What is a characteristic of a benign tumor mentioned in the text?
How does apoptosis relate to uncontrolled cell growth?
How does apoptosis relate to uncontrolled cell growth?
What triggers the activation of the gene coding for the p21 protein?
What triggers the activation of the gene coding for the p21 protein?
Which protein promotes apoptosis by binding to and blocking the action of the apoptosis inhibitor Bcl-2?
Which protein promotes apoptosis by binding to and blocking the action of the apoptosis inhibitor Bcl-2?
What is the main protein destruction machine in a cell?
What is the main protein destruction machine in a cell?
What happens when the DNA damage cannot be repaired and p53 is activated?
What happens when the DNA damage cannot be repaired and p53 is activated?
Which event leads to cell cycle arrest at the restriction point?
Which event leads to cell cycle arrest at the restriction point?
What role does the Rb protein play in cell cycle control?
What role does the Rb protein play in cell cycle control?
What event triggers the onset of S phase in cells stimulated by growth factors?
What event triggers the onset of S phase in cells stimulated by growth factors?
What happens to the Rb protein during M phase?
What happens to the Rb protein during M phase?
What event leads to the activation of checkpoint kinases and subsequent phosphorylation of the p53 protein?
What event leads to the activation of checkpoint kinases and subsequent phosphorylation of the p53 protein?
What is the role of the E2F transcription factor in cell cycle control?
What is the role of the E2F transcription factor in cell cycle control?
What is the role of the G1 Cdk-cyclin complex in cell cycle control?
What is the role of the G1 Cdk-cyclin complex in cell cycle control?
What is the primary role of the Mdm2 protein in relation to p53?
What is the primary role of the Mdm2 protein in relation to p53?
How does the accumulation of phosphorylated p53 lead to cell cycle arrest?
How does the accumulation of phosphorylated p53 lead to cell cycle arrest?
What is the role of the Puma protein in the p53 pathway?
What is the role of the Puma protein in the p53 pathway?
Which of the following protein kinases is responsible for initiating the p53 response to DNA damage?
Which of the following protein kinases is responsible for initiating the p53 response to DNA damage?
What is the consequence of the inhibition of Cdk-cyclin complexes by p21?
What is the consequence of the inhibition of Cdk-cyclin complexes by p21?
What is the primary function of the Bcl-2 protein in the p53 pathway?
What is the primary function of the Bcl-2 protein in the p53 pathway?
