10 Questions
What is the primary mechanism of action of many sleeping pills?
Enhancing the activity of gamma-aminobutyric acid (GABA)
What is the effect of benzodiazepines on GABAergic transmission?
They enhance the activity of GABA by binding to specific GABA-A receptor sites
What is the purpose of using benzodiazepines for insomnia?
To manage short-term insomnia due to their rapid onset of action and efficacy in inducing sleep
Which neurotransmitter is primarily responsible for promoting wakefulness?
Orexin
What is the effect of sleeping pills on neurotransmitter systems?
They can alter neurotransmitter levels or receptor activity to promote sleep
What is a characteristic of non-benzodiazepine hypnotics, such as zolpidem, compared to benzodiazepines?
They have a more selective action on GABA-A receptors
Which type of medication is particularly useful for promoting sleep onset in individuals with circadian rhythm disorders?
Melatonin receptor agonists
What is a potential drawback of using antihistamines as sleeping pills?
They can cause residual daytime sedation and cognitive impairment
What is a potential consequence of prolonged use of sleeping pills, particularly benzodiazepines and certain non-benzodiazepine hypnotics?
Tolerance and dependence
What is a recommended approach to sleep management, according to guidelines for the use of sleeping pills?
Using non-pharmacological approaches, such as CBT-I, as a first-line treatment
Learn about the pharmacology of sleeping pills, including their mechanisms of action, effects, and considerations. This quiz covers how sleeping pills work, including the enhancement of GABAergic transmission and the role of gamma-aminobutyric acid (GABA) in the brain.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
