Sleep Disorders (Overview)

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50 Questions

Which sleep disorder is characterized by difficulties initiating or maintaining sleep?

Insomnia

What is a widely used approach for managing insomnia that helps individuals identify and modify negative thoughts and behaviors associated with sleep?

Cognitive Behavioral Therapy (CBT)

Which of the following is NOT a recommended medication for insomnia treatment?

Valerian

What type of sleep aids should not be used long-term due to potential side effects and the risk of tolerance?

Over-the-counter (OTC) sleep aids

Which type of sedatives are generally preferred for long-term use in the treatment of insomnia?

Non-Benzodiazepine sedatives (non-BZDs)

What are some recommended sleep hygiene practices to improve sleep quality?

Reserving the bedroom for sleep-related activities only

Which natural remedies may provide relief for insomnia, although their effectiveness varies?

St. John's Wort and chamomile tea

For how long should Benzodiazepines (BZDs) be limited in the treatment of insomnia to avoid dependence?

7-10 days

What is the primary focus of non-drug treatments for insomnia?

Behavioral and lifestyle changes

What is a common sleep disorder characterized by pauses in breathing or shallow breathing during sleep?

Sleep apnea

Which sleep disorder is characterized by excessive daytime sleepiness, cataplexy, and sleep paralysis?

Narcolepsy

What is the main treatment for narcolepsy?

Stimulant medications

Which medication helps promote wakefulness in patients with narcolepsy?

Modafinil (Provigil)

What are potential side effects of Modafinil and Amodafinil?

Headaches and dizziness

What is the CNS depressant used for narcolepsy that can cause dizziness and somnolence?

Sodium Oxybate (Xyrem)

What is the main concern with the use of Sodium Oxybate?

High sodium levels

Which sleep disorder is characterized by difficulty falling asleep and staying asleep?

Insomnia

What are potential side effects of stimulant medications used for narcolepsy?

Headaches and dizziness

Which sleep disorder is characterized by involuntary leg movements and discomfort during sleep?

Restless legs syndrome

What is the classification of Sodium Oxybate (Xyrem)?

CNS depressant

Which of the following is NOT a recommended sleep hygiene practice?

Taking daytime naps after a poor night's sleep

What can help minimize anxiety related to falling asleep?

Turning the clock face away

Which of the following medications is NOT used for sleep onset difficulties?

Doxepin

Which medication is a melatonin agonist and may take weeks to have an effect?

Tasimelteon

Which sleep disorder is characterized by a "creeping" sensation or an irresistible urge to move the lower legs?

Restless Leg Syndrome

What is the underlying cause of Restless Leg Syndrome?

Dopamine imbalance in the brain

Which medication is NOT commonly prescribed for Restless Leg Syndrome?

Gabapentin

What is the recommended timing for taking Ropinirole for Restless Leg Syndrome?

1-3 hours before bedtime

Which medication can cause orthostasis and somnolence?

Pramipexole

What should be avoided when using the Rotigotine patch for Restless Leg Syndrome?

Applying the patch on the same site for more than 14 days

What are some non-drug treatment options for managing insomnia?

Non-drug treatments for insomnia primarily focus on behavioral and lifestyle changes such as Cognitive Behavioral Therapy (CBT) and practicing good sleep hygiene.

Why should over-the-counter (OTC) sleep aids be avoided long-term?

OTC sleep aids should not be used long-term due to potential side effects and the risk of tolerance.

Which natural remedies are not recommended for the treatment of insomnia?

Natural remedies like St. John's Wort and chamomile tea are not recommended for insomnia treatment.

What are the potential side effects of Modafinil and Amodafinil?

headaches, dizziness, anxiety, agitation, risk of severe rash

What is the classification of Sodium Oxybate (Xyrem)?

CNS depressant

What is the main concern with the use of Sodium Oxybate?

high sodium levels, part of the REMS Program, classified as a 'date-rape' drug (GHB)

What are some potential side effects of Zolpidem, Zaleplon, and Eszopiclone?

Some potential side effects of Zolpidem, Zaleplon, and Eszopiclone include somnolence, dizziness, ataxia, and parasomnias (abnormal sleep movements). These drugs also have a black box warning for CNS depression, next-day impairment, respiratory depression, and potential abuse or dependence.

What are the recommended medications for sleep maintenance difficulties?

The recommended medications for sleep maintenance difficulties include Doxepin, Suvorexant, Eszopiclone, Temazepam, and Zolpidem.

What are some potential side effects of Diphenhydramine and Doxylamine?

Some potential side effects of Diphenhydramine and Doxylamine include sedation, tolerance after 10 days, and anti-cholinergic effects such as dry mouth, urinary retention, blurry vision, and constipation. These medications should not be used in individuals with benign prostatic hyperplasia (BPH) or glaucoma.

What are the commonly prescribed medications for Restless Leg Syndrome?

The commonly prescribed medications for Restless Leg Syndrome include Pramipexole (Mirapex), Ropinirole (Requip), and Rotigotine (Neupro).

Match the following medications with their associated potential side effects:

Modafinil (Provigil) and Amodafinil (Nuvigil) = Headaches, dizziness, anxiety, agitation, and a risk of severe rash Sodium Oxybate (Xyrem) = Dizziness and somnolence Stimulant medications = Psychiatric hallucinations or abnormal dreams

Match the following medications with their primary usage:

Modafinil (Provigil) and Amodafinil (Nuvigil) = Promoting wakefulness in narcolepsy Sodium Oxybate (Xyrem) = Treatment for narcolepsy and cataplexy Stimulant medications = Treatment for attention-deficit/hyperactivity disorder (ADHD) and narcolepsy

Match the following descriptions with their associated sleep disorders:

Excessive daytime sleepiness, cataplexy, and sleep paralysis = Narcolepsy Sudden and uncontrollable episodes of falling asleep throughout the day and struggle to sleep at night = Narcolepsy

Match the following non-drug treatments for insomnia with their descriptions:

Cognitive Behavioral Therapy (CBT) = An approach that helps individuals identify and modify negative thoughts and behaviors associated with sleep Good sleep hygiene = Includes creating a sleep-conducive environment and maintaining a regular sleep schedule St. John's Wort and chamomile tea = Natural remedies that may provide relief, although their effectiveness varies Avoiding daytime naps = A practice that can help improve sleep quality

Match the following medications with their usage in insomnia treatment:

Over-the-counter (OTC) sleep aids = Should not be used long-term due to potential side effects and the risk of tolerance Non-Benzodiazepine sedatives (non-BZDs) = Generally preferred for long-term use Benzodiazepines (BZDs) = Should be limited to 7-10 days to avoid dependence Diphenhydramine, Melatonin, Tiagabine, Trazodone, and Valerian = Not recommended for insomnia treatment

Match the following elements of good sleep hygiene with their descriptions:

Sleep-conducive environment = Keeping the bedroom dark, quiet, and comfortable Regular sleep schedule = Helps regulate the body's internal clock Avoid daytime naps = Can interfere with nighttime sleep Bedroom for sleep-related activities only = Helps associate the bedroom with sleep

Match the following medications with their primary usage:

Zolpidem, Zaleplon, Eszopiclone = First line drug treatments for insomnia Doxepin = Used for sleep maintenance Pramipexole, Ropinirole = Commonly prescribed for Restless Leg Syndrome Gabapentin = Used for Restless Leg Syndrome, dose reduction needed if CrCl is below 62

Match the following medications with their brand names:

Zolpidem = Ambien, Zolpimist, Edluar SL, Intermezzo SL Zaleplon = Sonata Eszopiclone = Lunesta Suvorexant = Belsomra

Match the following medications to their associated side effects:

Zolpidem, Zaleplon, Eszopiclone = Somnolence, Dizziness, Ataxia, Parasomnias Suvorexant = Somnolence, Dizziness, Headache, Abnormal dreams Ramelteon = Somnolence, Dizziness Diphenhydramine, Doxylamine = Dry mouth, Urinary retention, Blurry vision, Constipation

Match the following medications to their precautions:

Zolpidem, Zaleplon, Eszopiclone = Black box warning for CNS depression, next-day impairment, respiratory depression, potential abuse or dependence Ramelteon = Should not be taken with fatty food Diphenhydramine, Doxylamine = Should not be used in individuals with benign prostatic hyperplasia (BPH) or glaucoma Gabapentin = May require a reduced dose if the patient's creatinine clearance (CrCl) is below 62

Test your knowledge on sleep disorders and learn effective strategies for understanding and managing them. Explore non-drug and drug treatment options, as well as lifestyle changes that can improve sleep quality.

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