chapter 10. quiz 2 Sleep and Anesthesia Comparison

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Questions and Answers

What differentiates sleep from anesthesia in terms of reversibility?

  • Anesthesia is spontaneously generated and terminated.
  • Anesthesia lacks EEG patterns.
  • Sleep shows ready reversibility by noxious stimuli. (correct)
  • Sleep lacks modulation of brainstem autonomic function.

How do the EEG patterns differ between sleep and anesthesia?

  • They exhibit sharp α–θ EEG transitions.
  • They have different frequencies and types of activation. (correct)
  • They both show a uniform EEG picture.
  • They have the same EEG patterns.

What is unique about the transitions in consciousness between wakefulness and sleep compared to anesthesia?

  • Sleep has no transient stages during transitions. (correct)
  • Anesthesia requires drug elimination to transition.
  • Anesthesia has sharp α–θ EEG transitions.
  • Sleep involves continuous decrease in consciousness.

How does arousal differ between physiologic sleep and drug-induced unconsciousness?

<p>Physiologic sleep individuals can be aroused with sufficient stimulation. (C)</p> Signup and view all the answers

What is one key similarity between the neurons active during sleep in the VLPO and the neurons activated by certain anesthetics?

<p>Both types of neurons are inhibited by the VLPO. (C)</p> Signup and view all the answers

Why is the direct inhibition of the TMN insufficient to produce unconsciousness during anesthesia?

<p>Because interaction with sleep-promoting nuclei alone does not lead to unconsciousness. (B)</p> Signup and view all the answers

How does activation of the VLPO contribute to anesthesia according to the text?

<p>By inhibiting the arousal nuclei and affecting transitions between wakefulness and sleep. (A)</p> Signup and view all the answers

How do most anesthetics affect sleep architecture during the early postoperative period?

<p>Decrease REM sleep duration (A)</p> Signup and view all the answers

What is the impact of low dose propofol on REM sleep according to the text?

<p>Facilitates REM sleep (C)</p> Signup and view all the answers

How does anesthesia potentially interfere with circadian rhythms?

<p>By influencing GABA and NMDA receptors (D)</p> Signup and view all the answers

What effect does long-term ventilation have on REM sleep according to the text?

<p>Diminishes REM sleep (B)</p> Signup and view all the answers

1st postoperative night characterised by?

<p>decrease in REM sleep. (A)</p> Signup and view all the answers

anesthesia and painful surgical procedures affect sleep and circadian rhythms for as long as

<p>6 month (C)</p> Signup and view all the answers

What is a common perioperative complication associated with patients with OSA?

<p>Newly detected Postoperative atrial fibrillation (B)</p> Signup and view all the answers

Which factor is NOT associated with the increased risk of perioperative complications in patients with OSA?

<p>Low blood pressure (B)</p> Signup and view all the answers

What is a common outcome observed in patients with sleep-disordered breathing (SDB) after surgery?

<p>Higher rates of severe perioperative complications (B)</p> Signup and view all the answers

Which postoperative night are patients with OSA most vulnerable to hypoxia according to the text?

<p>Night 2 or 3 (B)</p> Signup and view all the answers

What is a distinctive feature of patients with obesity hypoventilation syndrome (OHS) compared to obese patients?

<p>Higher mechanical ventilation rates (D)</p> Signup and view all the answers

Why is it challenging to determine the specific effect of OSA on perioperative complications?

<p>OSA comorbidities have similar effects on outcomes (A)</p> Signup and view all the answers

OSA is associated with higher rate for

<p>is not associated with difficult tracheal intubation or mask ventilation. (D)</p> Signup and view all the answers

What drives the perioperative algorithm for patients with sleep-disordered breathing?

<p>CPAP use preoperatively (C)</p> Signup and view all the answers

For obese patients at risk for sleep apnea scheduled for surgery, when is a sleep study considered necessary based on the text?

<p>Only for high-risk patients (B)</p> Signup and view all the answers

In the perioperative period, which group of patients may require a preoperative sleep medicine consultation and/or CPAP prescription according to the text?

<p>Patients with procedural and comorbidity-based risk factors (A)</p> Signup and view all the answers

What is the primary consideration for the standard of care in perioperative management of patients with sleep-disordered breathing?

<p>Severity of the disease (C)</p> Signup and view all the answers

What drives the perioperative management algorithm for patients with sleep-disordered breathing?

<p>A combination of disease severity, comorbidities, and procedural threat (C)</p> Signup and view all the answers

In perioperative management, what is recommended for patients who have been prescribed CPAP preoperatively?

<p>Continue using CPAP perioperatively (C)</p> Signup and view all the answers

What is the suggested approach for high-risk patients with several risk factors in the perioperative period according to the text?

<p>Having a sleep medicine consultation and possibly a CPAP prescription (C)</p> Signup and view all the answers

What determines whether a preoperative sleep medicine consultation and/or a CPAP prescription may be needed for certain patients?

<p>Risk factors related to the surgery and comorbidities (D)</p> Signup and view all the answers

What is the main purpose of the STOP-Bang questionnaire in preoperative screening for obstructive sleep apnea?

<p>Identify comorbidities of OSA that increase perioperative complications (C)</p> Signup and view all the answers

What is the role of a clinical examination in preoperative screening for obstructive sleep apnea?

<p>Provide a cost-effective initial assessment (C)</p> Signup and view all the answers

Why is polysomnography (PSG) not recommended for preoperative screening despite its ability to identify sleep-disordered breathing?

<p>It is cost-prohibitive and inconvenient (A)</p> Signup and view all the answers

In patients undergoing high-risk surgical procedures, what additional screening method is recommended alongside clinical examination?

<p>standardized and validated questionnaires (e.g., Berlin). (B)</p> Signup and view all the answers

What symptom of obesity hypoventilation syndrome (OHS) can be detected through a blood gas analysis?

<p>Daytime hypercapnia (D)</p> Signup and view all the answers

What should be included in the preoperative assessment of patients scheduled for low-risk procedures and have no previously diagnosed sleep-disordered breathing?

<p>Standard perioperative monitoring (D)</p> Signup and view all the answers

What method is recommended to detect hypercapnia as a major symptom of obesity hypoventilation syndrome (OHS)?

<p>Blood gas analysis (B)</p> Signup and view all the answers

Which clinical condition must be excluded to diagnose obesity hypoventilation syndrome (OHS) according to the text?

<p>Kyphoscoliosis (C)</p> Signup and view all the answers

What combination of factors indicates a high risk of obesity hypoventilation syndrome (OHS) in patients?

<p>High carbon dioxide levels and low oxygen levels (C)</p> Signup and view all the answers

What is the criterion for awake daytime hypercapnia that suggests a potential diagnosis of obesity hypoventilation syndrome (OHS)?

<p>$PaCO_2 &gt; 45$ mm Hg (C)</p> Signup and view all the answers

What is the highly sensitive method for diagnosing obesity hypoventilation syndrome (OHS) according to the text?

<p>Venous bicarbonate concentration test (B)</p> Signup and view all the answers

What is a recommended strategy during the preanesthesia period to minimize the chance of postoperative sedation?

<p>Consider regional anesthetic techniques (B)</p> Signup and view all the answers

In the induction strategy for anesthesia, what should be utilized immediately after intubation to maintain lung volume during surgery?

<p>Lung recruitment maneuvers with PEEP (C)</p> Signup and view all the answers

What should be reduced whenever possible during intraoperative management ?

<p>Use of sedatives and narcotics (D)</p> Signup and view all the answers

What position is preferred for patients in the PACU bed to minimize gravitational effects on the upper airway?

<p>45-degree elevated upper body (B)</p> Signup and view all the answers

Which of the following is a recommended consideration for post-extubation care in the PACU?

<p>Upper body elevation by 45 degrees (B)</p> Signup and view all the answers

What should be documented for monitoring and treatment in case of impaired respiratory function in the PACU?

<p>A defined plan including noninvasive ventilation (A)</p> Signup and view all the answers

What should be avoided when extubating patients to reduce the risk of postoperative airway collapse?

<p>Extubating patients during hypocarbia (C)</p> Signup and view all the answers

To prevent residual neuromuscular blockade and reduce the risk of postoperative respiratory complications, what method should be used when administering nondepolarizing neuromuscular blocking drugs?

<p>Titrate optimally by monitoring neuromuscular transmission (A)</p> Signup and view all the answers

Which drug can help maintain upper airway patency during loss of consciousness and sleep, making it a potential option for postoperative pain therapy in high-risk patients?

<p>Ketamine (C)</p> Signup and view all the answers

When should the effects of neuromuscular blockade be reversed to avoid impairing upper airway function?

<p>Only when present (C)</p> Signup and view all the answers

What can help in achieving postoperative pain therapy for patients at high risk of airway collapse?

<p>Ketamine (B)</p> Signup and view all the answers

What is the preferred positioning before intubation to improve maintenance of the passive pharyngeal airway in patients with obstructive sleep apnea (OSA)?

<p>Reverse Trendelenburg position (A)</p> Signup and view all the answers

Which drug type should be used with caution to reduce the duration of paralysis during intubation in patients with OSA?

<p>Nondepolarizing neuromuscular blocking drugs (C)</p> Signup and view all the answers

What immediate action should be considered after successful intubation to maintain lung volume during surgery for patients with OSA?

<p>Performing a lung recruitment maneuver (B)</p> Signup and view all the answers

Which compound types impair upper airway patency when administered during sedation for procedures like endoscopy?

<p>Opioids and GABAergic sedatives/hypnotics (A)</p> Signup and view all the answers

What is a major concern for patients who are vulnerable to respiratory complications during sedation without a device bypassing the collapsible upper airway?

<p>Sequelae of increased upper airway collapsibility (C)</p> Signup and view all the answers

What is a key consideration for postoperative care to prevent the development of postoperative negative pressure pulmonary edema?

<p>NIV (D)</p> Signup and view all the answers

What is a viable treatment option for postoperative respiratory failure that also helps in preventing deoxygenation?

<p>Non-invasive ventilation (NIV) (C)</p> Signup and view all the answers

In postoperative care, what should be conducted before discharging a patient from the post anesthesia care unit (PACU)?

<p>Performing a room air-challenge test (D)</p> Signup and view all the answers

What alternative positioning method is recommended for patients who do not tolerate an elevated upper body position in postoperative care?

<p>Positioning on the side (B)</p> Signup and view all the answers

What is a key precaution to take when opioids are combined with sedatives or hypnotics?

<p>Consider reducing opioid use if feasible (D)</p> Signup and view all the answers

For patients at high risk of obstructive sleep apnea (OSA), what is a beneficial approach in the early postoperative period?

<p>Maintain CPAP treatment throughout the early postoperative period (B)</p> Signup and view all the answers

In patients being treated with CPAP at home, what should be ensured during the perioperative period?

<p>Check the functioning of the CPAP device preoperatively (C)</p> Signup and view all the answers

What is a recommended strategy to prevent airway collapse and maintain respiratory function in high-risk patients?

<p>Reduce opioid use whenever possible (B)</p> Signup and view all the answers

What contributes to the disrupted sleep-wake pattern seen in many ICU patients?

<p>Exposure to dim light during the day (A)</p> Signup and view all the answers

What is a common source of noise in the ICU environment?

<p>Medical and monitoring device alarms (D)</p> Signup and view all the answers

Which factor influences melatonin rhythm in the ICU setting?

<p>Increasing age (A)</p> Signup and view all the answers

What is a common characteristic of the EEG activity in ICU patients receiving sedatives or mechanical ventilation?

<p>Does not fit into standard criteria for sleep and wakefulness (D)</p> Signup and view all the answers

How does exposure to dim light in the ICU affect internal circadian rhythms?

<p>Disrupts alignment with external 24-hour rhythm (D)</p> Signup and view all the answers

What percentage of sleep in the ICU occurs during the day?

<p>~50% (C)</p> Signup and view all the answers

What effect do β-blockers have on melatonin secretion?

<p>Decrease melatonin secretion (D)</p> Signup and view all the answers

How do opioids affect REM sleep according to the text?

<p>Reduce REM-sleep duration (D)</p> Signup and view all the answers

Which medication inconsistently affects melatonin ?

<p>Benzodiazepines (B)</p> Signup and view all the answers

What is the recommended approach to improving sleep quality for ICU patients based on the text?

<p>Reduce light and noise exposure during the night (A)</p> Signup and view all the answers

Which neurotransmitter system do medications used for treating insomnia in the ICU interact with?

<p>GABA system (D)</p> Signup and view all the answers

What physiological consequence of sleep disturbance in the ICU can lead to an increased risk of infections?

<p>Increased low-grade inflammation (D)</p> Signup and view all the answers

Which endocrinological effect is a result of sleep disturbance in the ICU?

<p>impaired glucose tolerance (C)</p> Signup and view all the answers

How does sleep disturbance in the ICU impact respiratory function?

<p>Decreased ventilatory CO2 response (B)</p> Signup and view all the answers

Which cognitive function is affected by sleep disturbance in the ICU?

<p>increase delirium risk (B)</p> Signup and view all the answers

What is a consequence of sleep disturbance in the ICU on metabolic function?

<p>Increased catabolic states (B)</p> Signup and view all the answers

What is the prevalence of narcolepsy?

<p>0.05-0.08% (A)</p> Signup and view all the answers

Which neurotransmitter system is primarily affected in narcolepsy?

<p>orexin neurons pathways (D)</p> Signup and view all the answers

What distinguishes narcolepsy with cataplexy from narcolepsy without cataplexy?

<p>Experience of sudden loss of muscle tone (A)</p> Signup and view all the answers

What is the suggested origin of narcolepsy according to the text?

<p>Autoimmune response against orexin neurons (B)</p> Signup and view all the answers

Which treatment is specifically effective for cataplexy in narcolepsy?

<p>Tricyclic antidepressants (C)</p> Signup and view all the answers

How should medical treatment for narcolepsy be supported according to the text?

<p>With behavioral therapy (D)</p> Signup and view all the answers

What is a recommended approach to anesthesia for patients with narcolepsy based on the text?

<p>Consideration of regional anesthesia (D)</p> Signup and view all the answers

Why is it important to maintain medical treatment for narcolepsy during the preoperative period?

<p>To prevent postsurgical hypersomnia (D)</p> Signup and view all the answers

What is a cardinal feature used to define restless legs syndrome?

<p>Urge to move the limbs (D)</p> Signup and view all the answers

What is a common condition that may cause isolated periodic limb movement during sleep?

<p>Excessive caffeine consumption (C)</p> Signup and view all the answers

What is the main consequence of frequent arousals due to limb movements during sleep in patients with periodic limb movement disorder?

<p>Sleep disruption (B)</p> Signup and view all the answers

Which medication type is mentioned as a potential cause of symptoms similar to restless legs syndrome?

<p>Antidepressants (B)</p> Signup and view all the answers

In which group of patients would a polysomnography (PSG) test be recommended according to the text?

<p>Patients at risk of sleep-disordered breathing (A)</p> Signup and view all the answers

What is the recommended 1st line treatment for restless legs syndrome according to the text?

<p>dopamine agonists (B)</p> Signup and view all the answers

Which medication should be avoided for patients with restless legs syndrome based on the text?

<p>Neuroleptics (A)</p> Signup and view all the answers

Why might ketamine be considered a superior anesthetic drug for patients with restless legs syndrome according to the text?

<p>It enhances dopamine levels in the brain (B)</p> Signup and view all the answers

What is the best approach to provide symptom relief in patients with restless legs syndrome after surgery according to the text?

<p>Early mobilization (A)</p> Signup and view all the answers

What should be monitored closely before, during, and after surgery to prevent symptomatic restless legs syndrome symptoms?

<p>Iron and ferritin blood levels (B)</p> Signup and view all the answers

Which drug administration during and after surgery might benefit patients with restless legs syndrome?

<p>Benzodiazepines (C)</p> Signup and view all the answers

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