Skin Drugs and Epidermal Layers Quiz
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Questions and Answers

What is the major function of the dermis?

  • Conversion of keratin
  • To provide support and nourishment for the epidermis (correct)
  • Production of new epidermal cells
  • Produce melanin
  • Which layer of the epidermis is referred to as the cornified layer?

  • Stratum germinativum
  • Stratum corneum (correct)
  • Middle layer
  • Basal layer
  • What are ointments primarily composed of?

  • Water
  • Collagen
  • Melanin
  • Oil or petroleum jelly base (correct)
  • Where do all epidermal cells arise from?

    <p>Stratum germinativum</p> Signup and view all the answers

    What gives the outer layer of the epidermis a rough, horny texture?

    <p>Conversion of keratin</p> Signup and view all the answers

    Which cells in the basal layer are mitotically active?

    <p>Epidermal cells</p> Signup and view all the answers

    What is the main component of the dermis?

    <p>Collagen</p> Signup and view all the answers

    Which skin pigment determines skin color?

    <p>Melanin</p> Signup and view all the answers

    What is the function of sebaceous glands?

    <p>Produce sebum</p> Signup and view all the answers

    What is the role of the subcutaneous tissue?

    <p>Store fat</p> Signup and view all the answers

    Which type of formulation is recommended for weeping or oozing skin conditions?

    <p>Ointments</p> Signup and view all the answers

    What is the primary difference between creams and lotions?

    <p>Consistency</p> Signup and view all the answers

    Which type of formulation is most suitable for oily skin?

    <p>Gels</p> Signup and view all the answers

    What is the purpose of foams in dermatologic conditions?

    <p>Cooling</p> Signup and view all the answers

    Which areas of the body are considered less permeable for drug absorption?

    <p>Palms and soles</p> Signup and view all the answers

    What factor greatly increases drug absorption from topical glucocorticoids?

    <p>Occlusive dressing</p> Signup and view all the answers

    What are the potential adverse effects of prolonged glucocorticoid use on the skin?

    <p>Telangiectasias</p> Signup and view all the answers

    What is the purpose of keratolytic agents in dermatology?

    <p>To promote shedding of the stratum corneum</p> Signup and view all the answers

    Which concentration range is ideal to achieve keratolytic effects?

    <p>3% to 6%</p> Signup and view all the answers

    What is likely to happen if concentrations of keratolytic agents are above 6%?

    <p>Tissue injury</p> Signup and view all the answers

    What are some symptoms of systemic toxicity from keratolytic agents?

    <p>Tinnitus, hyperpnea, and psychologic disturbances</p> Signup and view all the answers

    Which compound promotes peeling and drying in the treatment of skin conditions?

    <p>Sulfur</p> Signup and view all the answers

    What is the primary mechanism of action of benzoyl peroxide in acne treatment?

    <p>Releasing active oxygen</p> Signup and view all the answers

    What is a common side effect of dapsone gel in acne therapy?

    <p>Oiliness</p> Signup and view all the answers

    Which drug is considered the principal agent for severe acne?

    <p>Isotretinoin</p> Signup and view all the answers

    In treating moderate acne, what can be used in combination with oral antibiotics?

    <p>Benzoyl peroxide</p> Signup and view all the answers

    What is the common use of azelaic acid in dermatology?

    <p>Treatment of mild to moderate acne</p> Signup and view all the answers

    Which drug can be combined with clindamycin to prevent resistance development in acne treatment?

    <p>Benzoyl peroxide</p> Signup and view all the answers

    Which topical retinoid is indicated for acne, wrinkles, and psoriasis?

    <p>Tazarotene</p> Signup and view all the answers

    What kind of receptor sites does trifarotene (Aklief) target compared to other retinoids?

    <p>1</p> Signup and view all the answers

    What is the cost of trifarotene (Aklief) for 45 grams?

    <p>$575</p> Signup and view all the answers

    Which antibiotic is less commonly associated with resistance when used in acne treatment?

    <p>Minocycline</p> Signup and view all the answers

    Which topical retinoid is available over-the-counter?

    <p>Adapalene</p> Signup and view all the answers

    What is the primary purpose of oral antibiotics in acne therapy?

    <p>Fighting bacterial infection</p> Signup and view all the answers

    Which topical retinoid is used to remove fine wrinkles?

    <p>Tretinoin</p> Signup and view all the answers

    What adverse effects should patients be informed about when starting topical tretinoin treatment?

    <p>Blistering, peeling, crusting, burning</p> Signup and view all the answers

    What advice should be given to a patient starting topical tretinoin therapy regarding initial acne changes?

    <p>Acne may worsen initially.</p> Signup and view all the answers

    What advice should be given to a patient regarding the frequency of starting topical tretinoin?

    <p>Begin slowly every other day.</p> Signup and view all the answers

    Why are oral antibiotics like cephalexin only indicated for widespread skin infections in patients with eczema?

    <p>To reduce the risk of antimicrobial resistance development</p> Signup and view all the answers

    Which characteristic distinguishes psoriasis from eczema?

    <p>Presence of silver scales</p> Signup and view all the answers

    What is the most common side effect of Kunecatechins ointment?

    <p>Edema</p> Signup and view all the answers

    Why is the erratic course of psoriasis mentioned in the text?

    <p>To describe the varied progression over time</p> Signup and view all the answers

    Which condition is Kunecatechins ointment specifically indicated for?

    <p>External genital warts</p> Signup and view all the answers

    What is the primary cause of common warts on the hands and feet?

    <p>Viral infection</p> Signup and view all the answers

    What is the primary mechanism of action of glucocorticoids in psoriasis treatment?

    <p>Suppressing inflammatory cell activity</p> Signup and view all the answers

    Which treatment option is NOT recommended for eczema due to its possible risks mentioned in the text?

    <p>Oral antibiotics</p> Signup and view all the answers

    Which neuromuscular disorder should Botox be used with caution in due to its potential to intensify muscle paralysis?

    <p>Multiple sclerosis</p> Signup and view all the answers

    What is the main symptom of seborrheic dermatitis?

    <p>Scaling of the scalp and face</p> Signup and view all the answers

    What is the significance of accelerated maturation of epidermal cells in psoriasis?

    <p>To promote plaque formation in psoriasis lesions</p> Signup and view all the answers

    What is the primary mechanism of action of OnabotulinumtoxinA (Botox) injections for cosmetic use?

    <p>Temporary muscle paralysis</p> Signup and view all the answers

    Which type of light is used in photo therapy for managing psoriasis?

    <p>UV light</p> Signup and view all the answers

    What is the primary mechanism of action of coal tar in treating psoriasis?

    <p>Enzyme inhibition</p> Signup and view all the answers

    Which drug should be avoided during pregnancy and a period after for patients with psoriasis due to its adverse effects?

    <p>Methotrexate</p> Signup and view all the answers

    What is the primary cause of actinic keratosis?

    <p>Exposure to sunlight</p> Signup and view all the answers

    Which biologic agent is NOT approved for treating psoriasis?

    <p>Tocilizumab</p> Signup and view all the answers

    How do topical steroids primarily contribute to treating psoriasis?

    <p>By reducing inflammation</p> Signup and view all the answers

    Which medication for venereal warts should be used cautiously due to its highly caustic nature?

    <p>Podophyllin</p> Signup and view all the answers

    What is a potential systemic adverse reaction of applying podophyllin to large areas?

    <p>Kidney damage</p> Signup and view all the answers

    How does imiquimod work in treating venereal warts?

    <p>Stimulates immune responses to the virus</p> Signup and view all the answers

    Which medication must not be used during pregnancy due to its teratogenic effects?

    <p>Podofilox</p> Signup and view all the answers

    What action should be taken if excessive Bichloroacetic acid or Trichloroacetic acid solution is applied?

    <p>Neutralize with soap or sodium bicarbonate</p> Signup and view all the answers

    What distinguishes Podofilox from Imiquimod in treating venereal warts?

    <p>Imiquimod stimulates immune responses but works faster</p> Signup and view all the answers

    What is the most convenient application schedule for Xolegel in the treatment of seborrhea?

    <p>Daily for 2 weeks</p> Signup and view all the answers

    Which topical antifungal agent is recommended for maintaining remission after yeast infection control in seborrhea treatment?

    <p>Pyrithione zinc</p> Signup and view all the answers

    Which topical medication should be used specifically in the treatment of tinea corporis?

    <p>Ketoconazole</p> Signup and view all the answers

    What is the primary reason women are advised to use the 2% solution of minoxidil for hair loss?

    <p>Less chance of side effects</p> Signup and view all the answers

    What adverse effect is commonly reported by men using finasteride for male-pattern baldness?

    <p>Reduced ejaculate volume</p> Signup and view all the answers

    What enzyme does eflornithine cream inhibit to prevent facial hair growth in women?

    <p>Ornithine decarboxylase</p> Signup and view all the answers

    What is the recommended application frequency for eflornithine cream?

    <p>Twice daily</p> Signup and view all the answers

    Which bacterial infection is stated to be the most common on the skin?

    <p>Impetigo</p> Signup and view all the answers

    Which organism is identified as the causative agent of impetigo?

    <p>Staphylococcus aureus</p> Signup and view all the answers

    What is the characteristic manifestation of nonbullous impetigo?

    <p>Macular papules</p> Signup and view all the answers

    Which of the following antibiotics is NOT commonly used to treat impetigo?

    <p>Metronidazole</p> Signup and view all the answers

    Which expensive topical antibiotic is mentioned as a treatment option for impetigo?

    <p>$270 for 15 grams</p> Signup and view all the answers

    What is the purpose of applying local anesthetics topically to the skin?

    <p>To relieve pain and itching</p> Signup and view all the answers

    For what purpose are cosmetics and sunscreens allowed after applying eflornithine cream?

    <p>To cover the treated area</p> Signup and view all the answers

    What advice should be given to women using eflornithine cream regarding washing the treated area?

    <p>Should not wash for at least 4 hours after application</p> Signup and view all the answers

    Which age group is most commonly affected by impetigo?

    <p>Children (2-5 years)</p> Signup and view all the answers

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