Podcast
Questions and Answers
How does a fracture in the diaphysis of a bone manifest?
How does a fracture in the diaphysis of a bone manifest?
- Break in the periosteum
- Break in the epiphysis
- Break in the articular cartilage
- Break in the diaphysis (correct)
What functional role does the endosteum serve within a bone?
What functional role does the endosteum serve within a bone?
- Lines/ covers the epiphysis
- Located at articular surfaces
- Covers bones
- Lines the medullary cavity (correct)
Muscle tendon fibers attach to bone by interlacing with what?
Muscle tendon fibers attach to bone by interlacing with what?
- Compact bone
- Ligaments
- Endosteum
- Periosteum (correct)
Which components collectively form the organic matrix of bone?
Which components collectively form the organic matrix of bone?
What is secreted by osteoblasts during bone formation?
What is secreted by osteoblasts during bone formation?
Erosion of bone mineral is performed by which cells?
Erosion of bone mineral is performed by which cells?
What is a non-primary function of the skeletal system?
What is a non-primary function of the skeletal system?
Bone formation relies on which organelles to synthesize organic matrix substances?
Bone formation relies on which organelles to synthesize organic matrix substances?
What is the main function of the haversian system?
What is the main function of the haversian system?
What specific process is described as appositional growth during intramembranous ossification?
What specific process is described as appositional growth during intramembranous ossification?
Which type of bone marrow is responsible for carrying out hematopoiesis?
Which type of bone marrow is responsible for carrying out hematopoiesis?
Where is the primary ossification center of a long bone located?
Where is the primary ossification center of a long bone located?
What is the primary function of the epiphyseal plate?
What is the primary function of the epiphyseal plate?
What is the first crucial step in the bone fracture healing process?
What is the first crucial step in the bone fracture healing process?
When does bone loss typically begin to outpace bone gain?
When does bone loss typically begin to outpace bone gain?
Which cells facilitate the enlargement of the medullary cavity during bone growth?
Which cells facilitate the enlargement of the medullary cavity during bone growth?
Which amongst these cartilage subtypes is the most profusely found?
Which amongst these cartilage subtypes is the most profusely found?
The pinna of the ear is supported by which type of cartilage?
The pinna of the ear is supported by which type of cartilage?
How might vitamin A and protein deficiency impact bone growth in juveniles?
How might vitamin A and protein deficiency impact bone growth in juveniles?
Which of the following elements does not comprise the mineral component of bone?
Which of the following elements does not comprise the mineral component of bone?
How does escalating osteoblast activity affect blood calcium levels and bone calcium content?
How does escalating osteoblast activity affect blood calcium levels and bone calcium content?
What effect does increased osteoclast activity have on blood calcium levels?
What effect does increased osteoclast activity have on blood calcium levels?
How are sesamoid bones classified?
How are sesamoid bones classified?
What characteristic is NOT associated with the diaphysis of a long bone?
What characteristic is NOT associated with the diaphysis of a long bone?
Which characteristic is NOT representative of epiphyses?
Which characteristic is NOT representative of epiphyses?
Which of the following bodily functions is dependent on the precise concentration of calcium ions in the blood?
Which of the following bodily functions is dependent on the precise concentration of calcium ions in the blood?
Parathyroid hormone influences which process?
Parathyroid hormone influences which process?
Which feature distinguishes bone from cartilage?
Which feature distinguishes bone from cartilage?
Which structure, among the following, does not consist of hyaline cartilage?
Which structure, among the following, does not consist of hyaline cartilage?
Which anatomical structure comprises elastic cartilage?
Which anatomical structure comprises elastic cartilage?
What describes a bone consisting solely of compact bone tissue?
What describes a bone consisting solely of compact bone tissue?
What is Cancellous bone?
What is Cancellous bone?
The humerus is an example of which class of bone?
The humerus is an example of which class of bone?
A vertebral bone is an example of which type of bone?
A vertebral bone is an example of which type of bone?
The tarsal bones belong to which group of bones?
The tarsal bones belong to which group of bones?
Which type of bone is the scapula?
Which type of bone is the scapula?
What is the composition of bone matrix?
What is the composition of bone matrix?
What percentage of the inorganic matrix is made up of hydroxyapatite crystals?
What percentage of the inorganic matrix is made up of hydroxyapatite crystals?
What is the name of the condition caused by vitamin D deficiency in children?
What is the name of the condition caused by vitamin D deficiency in children?
What are lengthwise-running central canals connected by?
What are lengthwise-running central canals connected by?
How does increased calcitonin levels affect blood calcium?
How does increased calcitonin levels affect blood calcium?
What hormone levels might one expect for a person taking calcium supplements?
What hormone levels might one expect for a person taking calcium supplements?
Which type of bone is characteristically located within tendons?
Which type of bone is characteristically located within tendons?
What are the concentric, cylinder-shaped layers of calcified bone matrix called?
What are the concentric, cylinder-shaped layers of calcified bone matrix called?
What are the minute spaces in the bone matrix that house bone cells?
What are the minute spaces in the bone matrix that house bone cells?
Where is diploë located?
Where is diploë located?
In the epiphyseal plate, where is the proliferating zone?
In the epiphyseal plate, where is the proliferating zone?
What epiphyseal plate zone is nearest the diaphysis?
What epiphyseal plate zone is nearest the diaphysis?
Besides calcium, bone provides a reservoir for which mineral?
Besides calcium, bone provides a reservoir for which mineral?
What delivers critical nutrients and oxygen to osteocytes?
What delivers critical nutrients and oxygen to osteocytes?
How would a significant reduction in endoplasmic reticulum and Golgi apparatus activity most directly impede bone formation?
How would a significant reduction in endoplasmic reticulum and Golgi apparatus activity most directly impede bone formation?
How does the Haversian system's structure contribute to its primary function of delivering nutrients?
How does the Haversian system's structure contribute to its primary function of delivering nutrients?
What effect would increased physical stress exerted on a bone have on the bone remodeling process, and which cells would mediate this change?
What effect would increased physical stress exerted on a bone have on the bone remodeling process, and which cells would mediate this change?
How might mutations affecting collagen synthesis impact the overall structure and function of bone?
How might mutations affecting collagen synthesis impact the overall structure and function of bone?
Which of the following activities would be most affected by damage to the epiphyseal plate?
Which of the following activities would be most affected by damage to the epiphyseal plate?
How does the distribution of hyaline cartilage in the skeletal system support its function in facilitating joint movement?
How does the distribution of hyaline cartilage in the skeletal system support its function in facilitating joint movement?
How would blocking the action of parathyroid hormone receptors in bone tissue impact calcium homeostasis?
How would blocking the action of parathyroid hormone receptors in bone tissue impact calcium homeostasis?
If osteoclast activity is locally suppressed within a bone, but osteoblast activity remains constant, what change would be expected in the bone's local density and calcium levels?
If osteoclast activity is locally suppressed within a bone, but osteoblast activity remains constant, what change would be expected in the bone's local density and calcium levels?
How does the presence of Volkmann's canals enhance the functionality of the Haversian system?
How does the presence of Volkmann's canals enhance the functionality of the Haversian system?
What is the functional significance of the arrangement of collagen fibers within bone matrix?
What is the functional significance of the arrangement of collagen fibers within bone matrix?
Which of the following scenarios would result in decreased thickness of the epiphyseal plate?
Which of the following scenarios would result in decreased thickness of the epiphyseal plate?
Why might a diet deficient in calcium and vitamin D lead to an increased risk of fractures?
Why might a diet deficient in calcium and vitamin D lead to an increased risk of fractures?
What impact would a mutation causing non-functional osteocytes have on bone maintenance and remodeling?
What impact would a mutation causing non-functional osteocytes have on bone maintenance and remodeling?
How does the process of appositional growth contribute to bone remodeling and adaptation to mechanical stress?
How does the process of appositional growth contribute to bone remodeling and adaptation to mechanical stress?
Compared to compact bone, how does the structural arrangement of spongy bone contribute to its function?
Compared to compact bone, how does the structural arrangement of spongy bone contribute to its function?
Which statement best describes the relationship between osteoblasts and bone density?
Which statement best describes the relationship between osteoblasts and bone density?
How does the skeletal system provide support to the respiratory system?
How does the skeletal system provide support to the respiratory system?
What is the significance of the periosteum's role in fracture repair?
What is the significance of the periosteum's role in fracture repair?
In the context of bone remodeling, what is the relationship between mechanical stress, osteocytes, and bone adaptation?
In the context of bone remodeling, what is the relationship between mechanical stress, osteocytes, and bone adaptation?
What role does the medullary cavity play in supporting the function of hematopoietic tissues?
What role does the medullary cavity play in supporting the function of hematopoietic tissues?
How would inhibiting chondrocyte proliferation in the epiphyseal plate affect bone development?
How would inhibiting chondrocyte proliferation in the epiphyseal plate affect bone development?
How do bone markings provide insight into the biomechanics and functional demands placed on bones?
How do bone markings provide insight into the biomechanics and functional demands placed on bones?
What is the interaction between calcitonin and osteoclasts?
What is the interaction between calcitonin and osteoclasts?
How do the proportions of collagen and hydroxyapatite affect the mechanical properties of bone?
How do the proportions of collagen and hydroxyapatite affect the mechanical properties of bone?
How does endochondral ossification differ from intramembranous ossification in the context of bone development?
How does endochondral ossification differ from intramembranous ossification in the context of bone development?
Which zone of the epiphyseal plate is primarily responsible for the rapid mitotic division of chondrocytes, directly contributing to bone elongation?
Which zone of the epiphyseal plate is primarily responsible for the rapid mitotic division of chondrocytes, directly contributing to bone elongation?
Why is maintaining a balance between bone deposition and resorption critical for skeletal health?
Why is maintaining a balance between bone deposition and resorption critical for skeletal health?
How is the arrangement of osteons in compact bone optimized to withstand mechanical stress?
How is the arrangement of osteons in compact bone optimized to withstand mechanical stress?
What is the relationship between an increase in calcitonin levels, osteoclast activity, and blood calcium levels?
What is the relationship between an increase in calcitonin levels, osteoclast activity, and blood calcium levels?
How might a tumor affecting red bone marrow function impact bone tissue?
How might a tumor affecting red bone marrow function impact bone tissue?
How do canaliculi facilitate communication and nutrient exchange within compact bone?
How do canaliculi facilitate communication and nutrient exchange within compact bone?
How do mechanical forces influence bone remodeling?
How do mechanical forces influence bone remodeling?
What is the role of hydroxyapatite in bone?
What is the role of hydroxyapatite in bone?
Which of the following describes the bone matrix?
Which of the following describes the bone matrix?
Flashcards
Diaphysis
Diaphysis
The shaft of a bone.
Endosteum
Endosteum
Tissue lining the medullary cavity.
Periosteum
Periosteum
Connects muscle tendon fibers to bone.
Organic matrix of bone
Organic matrix of bone
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Osteoblasts
Osteoblasts
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Osteoclasts
Osteoclasts
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Primary functions of bones
Primary functions of bones
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Cell organelles for matrix synthesis
Cell organelles for matrix synthesis
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Osteon (Haversian system)
Osteon (Haversian system)
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Appositional growth
Appositional growth
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Red bone marrow
Red bone marrow
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Primary ossification center
Primary ossification center
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Major purpose of epiphyseal plate
Major purpose of epiphyseal plate
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First step in healing a fracture
First step in healing a fracture
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Age when bone loss exceeds gain
Age when bone loss exceeds gain
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Medullary cavity in bone growth
Medullary cavity in bone growth
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Hyaline cartilage
Hyaline cartilage
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External ear composition
External ear composition
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Vitamin A and protein deficiency effect
Vitamin A and protein deficiency effect
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Not part of the inorganic matrix of bone
Not part of the inorganic matrix of bone
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Impact as osteoblast activity increases
Impact as osteoblast activity increases
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Impact as osteoclast activity increases
Impact as osteoclast activity increases
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Sesamoid bones
Sesamoid bones
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Not a characteristic of diaphysis
Not a characteristic of diaphysis
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Not a characteristic of the epiphyses
Not a characteristic of the epiphyses
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Dependent on calcium ions in the blood
Dependent on calcium ions in the blood
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The parathyroid hormone does not cause
The parathyroid hormone does not cause
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True of bone but not of cartilage
True of bone but not of cartilage
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Not made of hyaline cartilage
Not made of hyaline cartilage
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Not made of elastic cartilage
Not made of elastic cartilage
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Type of bone that consists only of compact bone
Type of bone that consists only of compact bone
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Cancellous bone
Cancellous bone
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Humerus
Humerus
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Vertebral bone
Vertebral bone
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Tarsal bones
Tarsal bones
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Scapula
Scapula
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Matrix of bone
Matrix of bone
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Hydroxyapatite crystals
Hydroxyapatite crystals
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Result of vitamin D deficiency in children
Result of vitamin D deficiency in children
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transverse-running canals
transverse-running canals
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Increase of calcitonin
Increase of calcitonin
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Diet rich in calcium
Diet rich in calcium
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Type of bone found in a tendon
Type of bone found in a tendon
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Cylinder-shaped layers of calcified bone matrix
Cylinder-shaped layers of calcified bone matrix
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Contain the bone cells
Contain the bone cells
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Diploë can be found
Diploë can be found
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The proliferating zone is in the:
The proliferating zone is in the:
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The zone of hypertrophy is in the:
The zone of hypertrophy is in the:
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Minerals act a reservoir for
Minerals act a reservoir for
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Small tubes in the osteon.
Small tubes in the osteon.
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Study Notes
Skeletal Tissues: Fractures and Bone Structure
- A fracture in the diaphysis is a break in the shaft of a bone.
- Endosteum lines the medullary cavity.
- Muscle tendon fibers attach to bone by interlacing with the periosteum.
- The organic matrix of bone consists of collagenous fibers, protein, and polysaccharides.
- Osteoblasts produce the organic matrix in bone formation.
- Osteoclasts are responsible for active erosion of bone minerals.
- Bones primarily function in mineral storage, protection, and hematopoiesis.
- Endoplasmic reticulum and the Golgi apparatus synthesize organic matrix substances in bone formation.
- The osteon, or Haversian system, delivers nutrients to and removes waste products from bone cells.
Bone Formation: Intramembranous Ossification and Hematopoiesis
- Appositional growth in intramembranous ossification refers to the addition of an outside layer of osseous tissue on flat bones.
- Hematopoiesis takes place in the red bone marrow.
- The primary ossification center of a long bone resides in the diaphysis.
- The major role of the epiphyseal plate is to lengthen long bones.
- The first step in healing a fracture is the formation of a fracture hematoma.
- Bone loss typically exceeds bone gain between the ages of 35 and 40.
- The medullary cavity enlarges in bone growth due to the activity of osteoclasts.
Cartilage and Bone Matrix
- Hyaline cartilage is the most abundant type of cartilage.
- The external ear's form is composed of elastic cartilage.
- Vitamin A and protein deficiency in young children causes a decrease in the thickness of epiphyseal plates in growing long bones.
- Collagen is not part of the inorganic matrix of bone.
- As osteoblast activity increases, the level of calcium in the blood decreases, while the amount of calcium in bone increases.
- As osteoclast activity increases, the level of calcium in the blood increases.
- Sesamoid bones are classified as irregular bones.
- The diaphysis is hollow and composed of compact bone.
- The epiphyses are made of spongy bone and contain red bone marrow.
- Blood clotting, nerve impulse transmission, and cardiac muscle contraction depend on the proper amount of calcium ions in the blood.
- Parathyroid hormone actions do not include stimulation of osteoblast activity.
- Canals linking blood vessels and cells are present in bone but not in cartilage.
- The external ear is not made of hyaline cartilage.
- The tip of the nose is not made of elastic cartilage.
- All types of bones (long, short, irregular) are composed of both compact and spongy bone.
- Cancellous bone is another term for spongy bone.
- The humerus is an example of a long bone.
- A vertebral bone is classified as an irregular bone.
- Tarsal bones are examples of short bones.
- The scapula is an example of a flat bone.
- The matrix of bone consists mostly of inorganic salts with a lesser amount of organic material.
- Hydroxyapatite crystals make up about 85% of the total inorganic matrix.
- Rickets results from vitamin D deficiency in children.
- Lengthwise-running central canals are connected by transverse-running Volkmann canals.
- As calcitonin levels in the blood increase, the amount of calcium in the blood decreases.
- A person with a diet rich in calcium would likely have both low levels of parathyroid hormone and high levels of calcitonin.
- Sesamoid bone is found in a tendon.
- Concentric, cylinder-shaped layers of calcified bone matrix are called lamellae.
- The small spaces in the matrix containing bone cells are called lacunae.
- Diploë is found in the middle of spongy bone.
- The proliferating zone is the second layer in the epiphyseal plate.
- The zone of hypertrophy is the third layer in the epiphyseal plate.
- Bones act as a reservoir for calcium and phosphorus.
- Canaliculi represents small tubes in the osteon that bring nutrients and oxygen to the osteocytes.
Axial vs. Appendicular Skeleton
- The clavicle is not part of the axial skeleton.
- Parietal bones are not part of the appendicular skeleton.
- The axial skeleton consists of 80 bones.
- The appendicular skeleton consists of 126 bones.
- A sinus is a cavity within a bone.
- A rib is part of the axial skeleton.
- The scapula is part of the appendicular skeleton.
- The lambdoid suture lies between the occipital and parietal bones.
- Mastoiditis is the inflammation of a sinus within the temporal bone.
- The occipital bone articulates with the first vertebra.
- The ethmoid bone makes up the upper parts of the nasal septum and side walls of the nasal cavity.
- The ethmoid bone is irregular, lying anterior to the sphenoid but posterior to the nasal bones.
- The mandible does not articulate with the maxillae.
- Damage to the cribriform plate carries the chance of infectious materials passing from the nose to the brain.
- A fontanel is an unossified area in an infant’s skull.
- The manubrium is the upper part of the sternum.
- The neck's skeletal framework consists of cervical vertebrae.
- 12 represents the number of thoracic vertebrae.
- All vertebrae except the sacrum and coccyx have a central opening called the vertebral foramen.
- The thoracic cage/thorax doesn't contain the scapula.
- The frontal bone is not part of the face,.
- The zygomatic bone does not contain paranasal sinuses.
- The occipital bone forms four joints with other bones.
- The maxillary bone has the largest of the paranasal sinuses.
- The zygomatic bone, also known as the malar bone.
- The sequence of the vertebral column from superior to inferior is cervical, thoracic, lumbar, sacral, and coccyx.
- The dens furnishes the axis for the rotation of the head from side to side.
- The adult skeleton has 206 bones.
- The bones of the middle ear are part of the axial skeleton.
- The mandible and vomer are the two unpaired facial bones.
- The palatine bone makes up part of the hard palate.
- The hyoid is the only bone in the body that does not articulate with another bone.
- The dens is part of the cervical vertebrae.
- There are seven true pairs of ribs in the body.
- The maxilla acts as the keystone for the face.
- The spinous process, vertebral foramen, and dens are associated with the vertebral column.
- The blunt cartilaginous lower tip of the sternum is called the xiphoid process.
- Floating ribs articulate with the vertebrae.
- The term fossa defines a depression in a bone, often receiving an articulating bone.
- The term ramus defines a curved portion of the bone.
- The term trochanter defines a large bump for the attachment of muscles.
- The term foramen defines a round hole in the bone through which vessels and nerves can pass.
- The frontal bone makes up the forehead and the anterior part of the calvaria.
- The parietal bones comprise the bulging top side of the cranium.
- Temporal bones make up the lower side of the cranium and part of its floor.
- The mandible forms the only movable joint in the skull with the temporal bone.
- The lacrimal bone is almost paper-thin, shaped and sized like a fingernail and lies posterior and lateral to each nasal bone.
- The eye, muscles of the eye, and lacrimal apparatus are found in the eye orbit.
- The fetal skull has fontanels, and the face is a greater part of the skull in the adult.
- The body of the sternum lies between the manubrium and the xiphoid process.
- Thoracic and sacral curvatures are defined as posterior convex curvatures of the spine.
- A newborn’s spine forms a continuous convex curve called a primary curvature.
Appendicular Skeleton: Bones and Features
- The collarbone is a layman's term for the clavicle.
- The trochlea and capitulum are distal portions of the humerus.
- The human hand has greater dexterity due to the freely movable joint of the thumb.
- The ulna articulates proximally with the humerus.
- Metacarpal bones form the framework of the hand.
- The pisiform bone can be found in the wrist.
- The false pelvis is the structure above the pelvic inlet, bordered by muscle in the front and bone along the sides and back.
- The pubis forms the anterior of the pelvic girdle.
- During childbirth, a baby passes through an imaginary plane called the pelvic outlet.
- The longest and heaviest bone in the body is the femur.
- A person with a fractured patella would expect discomfort in the knee.
- The scaphoid is not a tarsal bone.
- The pubic arch in the male is less than a 90-degree angle, the pelvic cavity is narrower in the male, and the coccyx is less flexible in the male.
- The bones of the upper extremity, going from proximal to distal, are the humerus, radius, carpals, and metacarpals.
- The bones of the lower extremity, going from proximal to distal, are the femur, tibia, tarsals, and metatarsals.
- After age 50, bone density slowly decreases due to a shift in remodeling activity.
- An inadequate supply of calcium and vitamin D, mechanical stress, and age contribute to skeletal variations.
Articulations: Classifications and Movements
- The structural classification of joints centers around the type of connective tissue that joins the bones together.
- Symphyses are not an example of a fibrous joint.
- Gomphoses represent unique joints between a tooth's root and the alveolar process of the mandible or maxilla.
- Synovial joints are the most movable in the body.
- Synovial articulations have a joint capsule structurally.
- Synarthrosis is considered an immovable joint in terms of function.
- A condyloid joint exemplifies a biaxial joint.
- The ball and socket joint allows for the widest range of movement.
- Menisci are pads of fibrocartilage located between the articulating ends of bones in some diarthroses.
- Menisci are fibrocartilage pads.
- Interphalangeal joints are examples of hinge joints.
- The knee joint exemplifies a hinge joint.
- The head of the radius articulating with the ulna exemplifies a pivot joint.
- The distal end of the radius articulating with the carpal bones exemplifies a condyloid (ellipsoidal) joint.
- A condyloid joint represents a biaxial joint.
- A gliding joint exemplifies a multiaxial joint.
- The ball and socket joint allows for the most movement.
- Moving a body part away from the medial plane constitutes abduction.
- Extending represents how kicking a football is accomplished .
- Moving a part of the body forward comprises protraction.
- Extension, increasing the angle between body parts.
- Stretching the foot down and back to point the toe comprises Plantar flexion.
- Circumduction represents the movement when the head is dropped to the shoulder, then to the chest, to the other shoulder, and toward the back.
- Tilting the foot upward, decreasing the angle between the top of the foot and the front of the leg, is called dorsiflexion.
- The rotator cuff muscles and tendons form a cufflike arrangement around the shoulder.
- Vertebral bodies are connected together by the posterior longitudinal ligament.
- The knee, largest and most frequently injured joint.
- Deterioration of the nucleus pulposus results in a "slipped disk."
- Rotator cuff surgery indicates significant stress on the shoulder.
- The glenoid labrum comprises a fibrocartilage that increases the depth of the glenoid cavity.
- Inflammation of the prepatellar bursa is indicated by the condition of "housemaid’s knee".
- Juvenile rheumatoid arthritis is an inflammatory joint disorder.
- Sutures are located in the skull only.
- Gomphoses are located in the mandible, maxilla, and both.
- Synchondroses have hyaline cartilage between articulating bones in a joint and are immovable joints.
- The occipital bone fitting into the atlas bone exemplifies Condyloid joint .
- The subacromial ligament isn't part of the hip joint.
- The ligamenta flava is located in none of the joints listed.
- The shape of the articulating surfaces of the bones influences the type of movement possible at a synovial joint.
- The opposite of dorsiflexion is plantar flexion.
- Eversion does not have a direct opposite among the options listed.
- A sprain affects Ligaments
- The joint between the distal ends of the radius and ulna exemplifies a Syndesmosis
- The periodontal membrane is associated with Gomphosis
- A Symphysis joint joins the two pubic bones together.
- Bursae, joint cavity and Menisci characterize a synovial joint.
- Saddle joints are located between the thumb metacarpal and the trapezium in the wrist.
- Bursae is defined as a closed, pillowlike structure filled with synovial fluid.
- Ligaments are defined by structures of a synovial joint as a strong cord of dense, white, fibrous connective tissue.
- The olecranon bursa is associated with the elbow joint.
- A goniometer reading of zero indicates that the joint is in the anatomical position.
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