Podcast
Questions and Answers
Which of the following is NOT a primary function of the skeletal system, as described in the text?
Which of the following is NOT a primary function of the skeletal system, as described in the text?
- Facilitating movement
- Regulating body temperature (correct)
- Protecting internal organs
- Producing blood cells
What specific substance, stored within the bone matrix, does the text identify as essential for muscle contractions and nerve impulse transmission?
What specific substance, stored within the bone matrix, does the text identify as essential for muscle contractions and nerve impulse transmission?
- Sodium
- Potassium
- Calcium (correct)
- Phosphorus
Which of these accurately describes the role of bones in movement?
Which of these accurately describes the role of bones in movement?
- They produce the impulses that cause muscles to contract and relax.
- They directly generate the force needed for movement.
- They function as levers, with joints serving as fulcrums. (correct)
- They act solely as anchors for muscles.
In what part of the skeletal system is adipose tissue, which acts as a source of energy, primarily found?
In what part of the skeletal system is adipose tissue, which acts as a source of energy, primarily found?
Besides calcium, which other mineral is specifically mentioned as being stored in the bone matrix?
Besides calcium, which other mineral is specifically mentioned as being stored in the bone matrix?
What is the primary function of cartilage, in the context of the skeletal system?
What is the primary function of cartilage, in the context of the skeletal system?
Which of the following sets of organs are correctly paired with their skeletal protectors?
Which of the following sets of organs are correctly paired with their skeletal protectors?
What percentage of total body calcium is estimated to be stored in the bones, as stated?
What percentage of total body calcium is estimated to be stored in the bones, as stated?
Which of the following is the primary site of hematopoiesis in adults?
Which of the following is the primary site of hematopoiesis in adults?
Which of the following best describes the function of osteocytes?
Which of the following best describes the function of osteocytes?
Which skeletal division includes the bones of the limbs and the pectoral and pelvic girdles?
Which skeletal division includes the bones of the limbs and the pectoral and pelvic girdles?
Which type of bone is predominantly found in the wrists and ankles?
Which type of bone is predominantly found in the wrists and ankles?
What is the primary role of osteoclasts in bone remodeling?
What is the primary role of osteoclasts in bone remodeling?
The roof of the skull, sternum, ribs, and scapulae primarily consist of what type of bones?
The roof of the skull, sternum, ribs, and scapulae primarily consist of what type of bones?
What is the term for the basic structural unit of compact bone?
What is the term for the basic structural unit of compact bone?
Which of the following best describes sesamoid bones?
Which of the following best describes sesamoid bones?
What are the channels that connect the central canals of adjacent osteons?
What are the channels that connect the central canals of adjacent osteons?
Which of the following distinguishes spongy bone from compact bone?
Which of the following distinguishes spongy bone from compact bone?
What is the name of the long tubular shaft that forms the axis of a typical long bone?
What is the name of the long tubular shaft that forms the axis of a typical long bone?
The ends of long bones are primarily made of which type of bone?
The ends of long bones are primarily made of which type of bone?
What is the significance of trabeculae in spongy bone?
What is the significance of trabeculae in spongy bone?
What is the primary function of articular cartilage?
What is the primary function of articular cartilage?
How does cartilage differ from bone?
How does cartilage differ from bone?
The epiphyseal plate is important for growth in the length of bones. What replaces it when the bone stops growing?
The epiphyseal plate is important for growth in the length of bones. What replaces it when the bone stops growing?
Which type of ossification does not use a cartilage model?
Which type of ossification does not use a cartilage model?
What is the outermost covering of a bone primarily made of dense irregular tissue?
What is the outermost covering of a bone primarily made of dense irregular tissue?
During intramembranous ossification, what is the uncalcified matrix secreted by osteoblasts called?
During intramembranous ossification, what is the uncalcified matrix secreted by osteoblasts called?
Which membrane lines the medullary cavity and other canals within the bone?
Which membrane lines the medullary cavity and other canals within the bone?
What structural component do both compact and spongy bone have in common?
What structural component do both compact and spongy bone have in common?
Which of the following cells is NOT capable of mitosis?
Which of the following cells is NOT capable of mitosis?
What is the name for the spongy bone found between two layers of compact bone in flat bones of the cranium?
What is the name for the spongy bone found between two layers of compact bone in flat bones of the cranium?
What type of fibers contribute to roughly one-third of the bone weight?
What type of fibers contribute to roughly one-third of the bone weight?
What is another term for spongy bone?
What is another term for spongy bone?
What is the primary mineral component of bone that gives it its hardness?
What is the primary mineral component of bone that gives it its hardness?
What is the term for the passageways in bone matrix that allow mature bone cells to communicate and receive nutrients?
What is the term for the passageways in bone matrix that allow mature bone cells to communicate and receive nutrients?
What cells differentiate from monocytes and macrophages?
What cells differentiate from monocytes and macrophages?
What is the role of yellow bone marrow?
What is the role of yellow bone marrow?
Where are the stem cells that produce osteoblasts found?
Where are the stem cells that produce osteoblasts found?
During intramembranous ossification, what structure is formed from osteoid secreted around capillaries?
During intramembranous ossification, what structure is formed from osteoid secreted around capillaries?
Which bones do NOT fully ossify at birth, allowing for deformation during passage through the birth canal?
Which bones do NOT fully ossify at birth, allowing for deformation during passage through the birth canal?
What is the initial skeletal precursor replaced during endochondral ossification?
What is the initial skeletal precursor replaced during endochondral ossification?
What is the perichondrium?
What is the perichondrium?
What causes the chondrocytes within the shaft to die during endochondral ossification?
What causes the chondrocytes within the shaft to die during endochondral ossification?
What is the periosteal bud composed of?
What is the periosteal bud composed of?
Which cells secrete osteoid during the formation of trabeculae?
Which cells secrete osteoid during the formation of trabeculae?
What process opens up the medullary cavity in the center of the diaphysis?
What process opens up the medullary cavity in the center of the diaphysis?
What characterizes the secondary ossification centers?
What characterizes the secondary ossification centers?
Which part of the epiphyseal plate contains small chondrocytes that secure the plate to the osseous tissue of the epiphysis?
Which part of the epiphyseal plate contains small chondrocytes that secure the plate to the osseous tissue of the epiphysis?
What is the primary role of the chondrocytes in the proliferative zone?
What is the primary role of the chondrocytes in the proliferative zone?
What happens to most of the chondrocytes in the zone of calcified matrix?
What happens to most of the chondrocytes in the zone of calcified matrix?
How does appositional growth lead to an increase in the diameter of bones?
How does appositional growth lead to an increase in the diameter of bones?
What process is responsible for a bone when the matrix is resorbed on one surface and deposited on another?
What process is responsible for a bone when the matrix is resorbed on one surface and deposited on another?
When does the process of bone modeling primarily take place?
When does the process of bone modeling primarily take place?
Which of the following is NOT a function of calcium ions in the human body?
Which of the following is NOT a function of calcium ions in the human body?
What is the primary effect of parathyroid hormone (PTH) on bone tissue?
What is the primary effect of parathyroid hormone (PTH) on bone tissue?
Which hormone directly opposes the effects of parathyroid hormone (PTH) in regulating blood calcium levels?
Which hormone directly opposes the effects of parathyroid hormone (PTH) in regulating blood calcium levels?
What is the effect of calcitonin on calcium absorption in the digestive tract?
What is the effect of calcitonin on calcium absorption in the digestive tract?
In individuals with hypercalcemia, which bodily system is typically underactive?
In individuals with hypercalcemia, which bodily system is typically underactive?
Which of the following best describes the effect of calcitriol on the kidneys?
Which of the following best describes the effect of calcitriol on the kidneys?
What condition is characterized by abnormally low levels of calcium in the blood?
What condition is characterized by abnormally low levels of calcium in the blood?
Which of the following bone disorders results from overactive osteoclasts?
Which of the following bone disorders results from overactive osteoclasts?
Which condition is characterized by the deposition of bone around skeletal muscles and normally soft tissues?
Which condition is characterized by the deposition of bone around skeletal muscles and normally soft tissues?
What is a key characteristic of Marfan syndrome, relating to bone structure?
What is a key characteristic of Marfan syndrome, relating to bone structure?
Which hormone promotes osteoblastic activity and the production of bone matrix and is reduced in women post-menopause?
Which hormone promotes osteoblastic activity and the production of bone matrix and is reduced in women post-menopause?
What is the primary cause of gigantism?
What is the primary cause of gigantism?
What is a distinguishing feature of acromegaly in terms of bone growth?
What is a distinguishing feature of acromegaly in terms of bone growth?
Which of the following describes the effect of calcitonin on osteoblasts?
Which of the following describes the effect of calcitonin on osteoblasts?
Which of the following best describes osteogenesis imperfecta?
Which of the following best describes osteogenesis imperfecta?
What is the primary function of osteoclasts during bone remodeling?
What is the primary function of osteoclasts during bone remodeling?
Which of the following is NOT a stage in bone fracture repair?
Which of the following is NOT a stage in bone fracture repair?
What is the role of collagen fibers in bone tissue?
What is the role of collagen fibers in bone tissue?
Which of the following best describes the initial response to a bone fracture?
Which of the following best describes the initial response to a bone fracture?
How does mechanical stress affect bone tissue?
How does mechanical stress affect bone tissue?
Which nutrient is most essential for the proper absorption of calcium in the small intestine?
Which nutrient is most essential for the proper absorption of calcium in the small intestine?
What is the primary function of calcitriol?
What is the primary function of calcitriol?
Which hormone is responsible for the growth spurt during adolescence?
Which hormone is responsible for the growth spurt during adolescence?
Why is resistance training more effective than cardiovascular activities for increasing bone density?
Why is resistance training more effective than cardiovascular activities for increasing bone density?
What is the role of osteoblasts during bone remodeling?
What is the role of osteoblasts during bone remodeling?
Which nutrient is most associated with bone mineralization through its interaction with hydroxyapatite crystals?
Which nutrient is most associated with bone mineralization through its interaction with hydroxyapatite crystals?
What determines the shape of bone after a fracture if not correctly reset?
What determines the shape of bone after a fracture if not correctly reset?
Which of the following is true regarding the effect of lack of mechanical stress on bone tissue?
Which of the following is true regarding the effect of lack of mechanical stress on bone tissue?
Which of the following is NOT a primary source of calcium?
Which of the following is NOT a primary source of calcium?
How do omega-3 fatty acids help with bone health?
How do omega-3 fatty acids help with bone health?
Flashcards
Osseous Tissue
Osseous Tissue
Hard, dense connective tissue that forms most of the adult skeleton.
Cartilage
Cartilage
Semi-rigid form of connective tissue that provides flexibility and smooth surfaces for movement.
Skeletal System
Skeletal System
A system composed of bones and cartilage, performing various functions for the body.
Support Function of Skeleton
Support Function of Skeleton
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Leverage and Movement Function of Skeleton
Leverage and Movement Function of Skeleton
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Protection Function of Skeleton
Protection Function of Skeleton
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Mineral Storage Function of Skeleton
Mineral Storage Function of Skeleton
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Energy Storage Function of Skeleton
Energy Storage Function of Skeleton
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Hematopoiesis
Hematopoiesis
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Red bone marrow
Red bone marrow
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Axial skeleton
Axial skeleton
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Appendicular skeleton
Appendicular skeleton
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Long bones
Long bones
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Short bones
Short bones
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Flat bones
Flat bones
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Irregular bones
Irregular bones
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Sesamoid bones
Sesamoid bones
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Diaphysis
Diaphysis
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Epiphyses
Epiphyses
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Metaphysis
Metaphysis
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Medullary cavity
Medullary cavity
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Periosteum
Periosteum
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Endosteum
Endosteum
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Osteoblasts
Osteoblasts
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Osteocytes
Osteocytes
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Osteoclasts
Osteoclasts
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Osteon
Osteon
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Central Canal (Haversian Canal)
Central Canal (Haversian Canal)
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Perforating Canals
Perforating Canals
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Lamellae
Lamellae
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Circumferential Lamellae
Circumferential Lamellae
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Interstitial Lamellae
Interstitial Lamellae
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Lacunae
Lacunae
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Canaliculi
Canaliculi
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Trabeculae
Trabeculae
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Intramembranous Ossification
Intramembranous Ossification
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Ossification Center
Ossification Center
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Osteoid
Osteoid
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Endochondral Ossification
Endochondral Ossification
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Perichondrium
Perichondrium
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Primary Ossification Center
Primary Ossification Center
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Periosteal Bud
Periosteal Bud
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Epiphyseal Plate
Epiphyseal Plate
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Reserve Zone
Reserve Zone
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Proliferative Zone
Proliferative Zone
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Zone of Maturation and Hypertrophy
Zone of Maturation and Hypertrophy
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Zone of Calcified Matrix
Zone of Calcified Matrix
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Appositional Growth
Appositional Growth
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Bone Modeling
Bone Modeling
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Bone Resorption
Bone Resorption
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Bone Deposition
Bone Deposition
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Fracture
Fracture
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Hematoma
Hematoma
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Hematoma Formation
Hematoma Formation
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Fibrocartilage Callus
Fibrocartilage Callus
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Fibrocartilage Callus Formation
Fibrocartilage Callus Formation
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Bony Callus Formation
Bony Callus Formation
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Bony Callus
Bony Callus
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Bone Weakening
Bone Weakening
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Resistance Training
Resistance Training
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Osteoporosis
Osteoporosis
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Calcium
Calcium
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Hypocalcemia
Hypocalcemia
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Hypercalcemia
Hypercalcemia
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Parathyroid Hormone (PTH)
Parathyroid Hormone (PTH)
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Calcitonin
Calcitonin
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Bone Formation
Bone Formation
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Fibrodysplasia Ossificans Progressiva (FOP)
Fibrodysplasia Ossificans Progressiva (FOP)
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Paget's Disease
Paget's Disease
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Osteogenesis Imperfecta (OI)
Osteogenesis Imperfecta (OI)
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Pituitary Growth Failure
Pituitary Growth Failure
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Achondroplasia
Achondroplasia
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Marfan Syndrome
Marfan Syndrome
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Gigantism
Gigantism
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Acromegaly
Acromegaly
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Study Notes
Osseous Tissue and Bone Structure
- Osseous tissue, or bone, is a hard, dense connective tissue forming most of the adult skeleton.
- Cartilage provides flexibility and smooth surfaces for movement in areas with bone movement.
- The skeletal system, comprised of bones and cartilage, supports the body, facilitates movement, protects internal organs, produces blood cells, and stores/releases minerals and fat.
Functions of the Skeletal System
- Support: Bones provide a framework for soft tissues and organs.
- Movement: Bones act as levers, with joints as fulcrums. This allows for a range of movements.
- Protection: Skeletal elements surround delicate tissues and organs. (e.g., ribs protect lungs, skull protects brain).
Mineral, Energy Storage, and Hematopoiesis
- Mineral Storage: Bone acts as a reservoir for calcium and phosphorus. These minerals are vital for body functions and can be released into the bloodstream. Over 98% of the body's calcium is in the bones.
- Energy Storage: Yellow bone marrow (adipose tissue) stores triglycerides as an energy source.
- Hematopoiesis: Red bone marrow, found in bone cavities, produces red blood cells, white blood cells, and platelets.
Bone Classification
- The adult skeleton has approximately 206 bones. It is divided into axial and appendicular skeletons.
- Axial Skeleton: (80 bones) skull, hyoid, sternum, rib cage, vertebral column, sacrum, coccyx.
- Appendicular Skeleton: (126 bones) limbs, pectoral girdle, pelvic girdle.
- Bones are classified by shape:
- Long Bones: Cylindrical, longer than wide (e.g., femur).
- Short Bones: Cube-like, equal dimensions (e.g., carpals, tarsals).
- Flat Bones: Thin, curved (e.g., skull, sternum).
- Irregular Bones: Complex shapes (e.g., vertebrae, pelvis).
- Sesamoid Bones: Small, flat, develop inside tendons (e.g., patella).
Bone Structure
-
Long Bones: Designed for force transmission, rich blood supply.
- Diaphysis: Long, tubular shaft, primarily compact bone.
- Epiphyses: Ends of bone, primarily spongy bone (trabecular bone).
- Articular Cartilage: Covers epiphyses for smooth articulation.
- Metaphysis: Region connecting diaphysis to epiphyses. Epiphyseal plate is the growth plate.
- Medullary Cavity: Shaft cavity containing bone marrow. Yellow marrow (fat) replaces red marrow during aging.
- Membranes:
- Periosteum: External covering of bone (blood vessels/nerves).
- Endosteum: Internal lining, site of bone growth/repair.
-
Compact Bone:
- Osteon: Basic functional unit.
- Central Canal (Haversian Canal): Contains blood vessels, nerves, etc.
- Perforating Canals (Volkmann's Canals): Connect central canals.
- Lamellae: Concentric rings of bone matrix.
- Lacunae: Spaces containing osteocytes.
- Canaliculi: Channels connecting lacunae to central canal.
-
Spongy Bone: Lattice-like network of trabeculae (matrix spikes). Provides strength & allows lightness. Red marrow fills spaces.
Bone Cells and Tissue
- Organic Osteoid: Collagen fibers (strong, flexible).
- Inorganic Hydroxyapatites: Mineral salts (calcium phosphate). Combining organic and inorganic components strengthen bone more than concrete and steel-reinforced concrete.
- Cells:
- Osteogenic Cells: Stem cells, produce osteoblasts.
- Osteoblasts: Immature bone cells, synthesize bone matrix.
- Osteocytes: Mature bone cells, maintain matrix.
- Osteoclasts: Bone-resorbing cells (remove & recycle).
Bone Formation and Development
- Cartilage Template: Bones develop using a cartilage template, crucial for fetal skeletal development.
- Intramembranous Ossification: Direct formation from mesenchymal tissue (flat bones, mandible).
- Endochondral Ossification: Bone replacing hyaline cartilage model (most bones).
How Bones Grow in Length and Width
- Longitudinal Growth: Occurs at epiphyseal plates (growth plates).
- Appositional Growth: Occurs at periosteal surface; remodeling also contributes.
Bone Remodeling/Fractures and Repair
- Bone Repair: Steps in fracture healing include hematoma formation, fibrocartilage callus formation, bony callus formation.
- Modeling: Matrix resorption and deposition in bone growth.
Exercise, Nutrition, and Hormones and Bone Tissue
- Exercise: Stimulates bone deposition.
- Nutrition: Calcium and Vitamin D are critical. Other nutrients (Vitamin K, Magnesium, Fluoride, Omega-3s) are also important.
- Hormones: Growth hormone, thyroxine, sex hormones, calcitriol, PTH and Calcitonin influence bone growth, maintenance, and remodeling.
Calcium Homeostasis and Disorders
- Calcium Homeostasis: The body tightly regulates blood calcium levels through interactions between the skeleton, kidneys, and digestive system.
- Hypocalcemia: Low calcium causes problems in multiple systems.
- Hypercalcemia: High calcium disrupts the nervous system.
Bone Disorders
- Pituitary growth failure (dwarfism), Achondroplasia: Results from abnormal growth hormone production & hyaline cartilage development.
- Marfan syndrome, Gigantism, Acromegaly: Genetic/hormonal disorders affecting bone growth.
- Fibrodysplasia Ossificans Progressiva (FOP), Paget's disease, Osteoporosis, Osteogenesis Imperfecta (OI): Bone disorders resulting from genetic mutations, overactive osteoclasts, or bone resorption exceeding formation.
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Description
Test your knowledge on the functions and structures of the skeletal system. This quiz covers various aspects, from mineral storage to the role of cartilage and the division of the skeleton. It's an essential assessment for students studying anatomy and physiology.