Skeletal Muscle Histology Quiz
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Questions and Answers

What is the primary function of skeletal muscle?

  • Regulating internal organs
  • Consciously controlled movement (correct)
  • Sensory perception
  • Involuntary movement
  • What is the role of mitochondria in muscle cells?

  • Storage of calcium ions
  • Production of ATP (correct)
  • Regulating muscle contraction
  • Synthesis of myofilaments
  • Which component directly covers the active sites on G-actin?

  • Tropomyosin (correct)
  • Myosin
  • F-actin
  • Troponin
  • What are the globular proteins that make up the strands of actin called?

    <p>G-actin</p> Signup and view all the answers

    How do transverse tubules function in muscle cells?

    <p>They allow action potentials to reach inside the cell</p> Signup and view all the answers

    Which type of muscle is primarily responsible for respiration?

    <p>Skeletal muscle</p> Signup and view all the answers

    What is the function of capillary beds in skeletal muscle?

    <p>Supply oxygen and nutrients</p> Signup and view all the answers

    What stabilizes joints and maintains body positions?

    <p>Skeletal muscles</p> Signup and view all the answers

    Which protein plays a critical role in muscle contraction regulation and interacts with calcium?

    <p>Troponin</p> Signup and view all the answers

    During muscle contraction, what happens to the active sites on G-actin?

    <p>They are opened when calcium binds to troponin</p> Signup and view all the answers

    What is the term for the unit of contractile proteins connected in series along the length of muscle?

    <p>Sarcomere</p> Signup and view all the answers

    Which structure is responsible for storing calcium in skeletal muscle cells?

    <p>Sarcoplasmic reticulum</p> Signup and view all the answers

    Which component of muscle fibers primarily enables elasticity?

    <p>Titin</p> Signup and view all the answers

    What is the role of the M-line in a sarcomere?

    <p>To anchor myosin filaments in place</p> Signup and view all the answers

    Which term describes the binding of myosin and actin to pull actin towards the M-line?

    <p>Cross-bridge</p> Signup and view all the answers

    What is found in the I-band of a sarcomere?

    <p>Only actin</p> Signup and view all the answers

    What is the primary role of dystrophin in muscle cells?

    <p>To connect actin filaments to the cell membrane</p> Signup and view all the answers

    Which muscle structure is responsible for dividing muscle fibers into individual units?

    <p>Endomysium</p> Signup and view all the answers

    Which of the following best describes the role of myoglobin in muscle tissue?

    <p>It stores and carries oxygen within the muscle</p> Signup and view all the answers

    What is the significance of the triad in muscle cells?

    <p>It facilitates the release of calcium during muscle contraction</p> Signup and view all the answers

    Study Notes

    Skeletal Muscle

    • Skeletal muscles are consciously controlled and responsible for body movement; they are attached to bones.
    • Muscle function includes posture maintenance, respiration and heat production.
    • Skeletal muscles are made up of muscle fibers (cells) that are long, cylindrical and multinucleated.
    • Myoblasts (immature muscle cells) fuse to form muscle fibers.
    • Muscle fibers exhibit striations (light and dark bands due to protein organization).
    • Skeletal muscles are composed primarily of muscle fibers (cells) surrounded by connective tissues, blood vessels, and nerves.

    Muscle Histology

    • Sarcolemma: The outer plasma membrane of a muscle cell.
    • Sarcoplasm: The cytoplasm of a muscle cell, containing many mitochondria (powerhouses of the cell) for ATP production
    • Myofibrils: Highly organized protein structures within muscle cells; they extend the entire length of the cell.
    • Myofilaments: Contractile proteins (actin and myosin) form repeating patterns, creating sarcomeres, which are the basic contractile units.
    • T-tubules: Invaginations of the sarcolemma, allowing action potentials to reach the interior of the muscle fiber, facilitating calcium release.
    • Sarcoplasmic Reticulum (SR) Smooth ER that stores calcium ions and releases them during muscle contractions.
    • Terminal cisternae: Enlarged regions of the SR adjacent to T-tubules, important for calcium storage.
    • Triad: A unit formed by a T-tubule and two terminal cisternae.

    Myofilaments

    • Actin (thin filaments): made up of G-actin (globular proteins) with active sites for myosin binding; also includes tropomyosin and troponin.
    • Myosin (thick filaments): made up of myosin filaments with heads that can bind to actin, driving contraction.
    • Sarcomere: Structural and functional unit of muscle fibers, extending from Z-disc to Z-disc.
    • Z-disc: Proteins that connect and organize actin filaments.
    • M-line: Protein structure in the middle of the sarcomere, connecting myosin filaments.
    • I-band: Region containing only actin filaments.
    • H-zone: Region containing only myosin filaments.
    • A-band: Region including both myosin and the overlapping portions of actin filaments.
    • Cross-bridges: Myosin heads binding to actin during muscle contraction
    • Myoglobin: Protein in muscle cells that binds and stores oxygen.
    • Glycogen granules: Store carbohydrates for energy.

    Gross Anatomy of Skeletal Muscle Structure

    • Tendons: Dense connective tissue attaching muscle to bone.
    • Fascicles: Bundles of muscle fibers.
    • Endomysium: Connective tissue surrounding individual muscle fibers.
    • Perimysium: Connective tissue surrounding fascicles.
    • Epimysium: Connective tissue surrounding the entire muscle.
    • Muscles are made up of multiple fascicles bundled together.

    Muscle Fiber Structure and Properties

    • Muscle cells are long, cylindrical, and multinucleated, containing myofibrils.
    • Muscles can shorten by contracting and can elongate from other forces.
    • They exhibit contractility (able to shorten), excitability (respond to APs), extensibility (extend beyond resting length), and elasticity (return to original length after extension).

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    Description

    Test your understanding of skeletal muscle structure and function in this quiz. Explore key terms such as sarcolemma, myofibrils, and the role of muscle fibers. Perfect for students studying muscle histology and anatomy.

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