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Questions and Answers

What does a protein level greater than 0.15g/day in urine indicate?

  • Impaired filtration (correct)
  • Kidney infection
  • Dehydration
  • Normal filtration
  • Which of the following conditions is indicated by the presence of glucose in urine?

  • Hyperglycemia (correct)
  • Dehydration
  • High protein intake
  • Kidney stones
  • What is the normal range for Creatinine levels in blood?

  • 60 – 150 mcmol/L
  • 45 – 90 mcmol/L
  • 90 – 120 mcmol/L
  • 53 – 103 mcmol/L (correct)
  • What role do stretch receptors in the bladder play during the micturition reflex?

    <p>Signal the need to void</p> Signup and view all the answers

    Which electrolyte is often the first to become abnormal in kidney function tests?

    <p>Potassium</p> Signup and view all the answers

    What is the normal range for the Glomerular Filtration Rate (GFR)?

    <p>Greater than 90 mL/min/1.73 m²</p> Signup and view all the answers

    What happens to the internal sphincter during the micturition reflex?

    <p>It relaxes</p> Signup and view all the answers

    What is the significance of finding leukocytes in urine analysis?

    <p>Indicator of infection</p> Signup and view all the answers

    What is a primary consequence of acute kidney injury (AKI)?

    <p>Rapid decline in the glomerular filtration rate (GFR)</p> Signup and view all the answers

    What is oliguria defined as in acute kidney failure?

    <p>Less than 500 ml of urine per day</p> Signup and view all the answers

    Which of the following is NOT a common cause of acute kidney injury?

    <p>Best diet adherence</p> Signup and view all the answers

    What dietary intervention is recommended for patients with acute kidney injury?

    <p>Low potassium diet</p> Signup and view all the answers

    What condition can result from prolonged urinary blockage?

    <p>Hydronephrosis</p> Signup and view all the answers

    What is the most common component of kidney stones?

    <p>Calcium</p> Signup and view all the answers

    Which clinical sign is commonly associated with the presence of kidney stones?

    <p>Severe flank pain</p> Signup and view all the answers

    Which of the following is a non-surgical treatment for kidney stones?

    <p>Pain management</p> Signup and view all the answers

    What should be monitored closely after lithotripsy procedures?

    <p>Intake and output</p> Signup and view all the answers

    What dietary factor increases the risk of developing kidney stones?

    <p>High oxalate diet</p> Signup and view all the answers

    What triggers the release of urine?

    <p>Voluntary relaxation of the external sphincter</p> Signup and view all the answers

    Which type of glomerulonephritis develops gradually over time?

    <p>Chronic glomerulonephritis</p> Signup and view all the answers

    How does urinary stasis in the bladder affect health?

    <p>Promotes bacterial growth and infection</p> Signup and view all the answers

    What is a significant result of decreased renal perfusion?

    <p>Tissue ischemia and insufficient filtration</p> Signup and view all the answers

    Which condition is associated with injuries to neurons in the spinal cord?

    <p>Urinary incontinence or retention</p> Signup and view all the answers

    What impact does increased fluid intake have on urine production?

    <p>Enhances the rate of urine production</p> Signup and view all the answers

    What measurement serves as an indicator of decreased renal function?

    <p>Elevated blood urea nitrogen (BUN) levels</p> Signup and view all the answers

    Which factor does NOT impact urinary motility?

    <p>Exercise levels</p> Signup and view all the answers

    What is the primary function of the renal system?

    <p>Management of body fluids and blood pressure</p> Signup and view all the answers

    Which substances are typically filtered in the glomerulus?

    <p>Water, ions, glucose, and small proteins</p> Signup and view all the answers

    In which part of the nephron does most reabsorption of sodium occur?

    <p>Proximal convoluted tubule</p> Signup and view all the answers

    How does active transport in the nephron differ from passive transport?

    <p>Active transport requires energy to move substances against a concentration gradient.</p> Signup and view all the answers

    What role does aldosterone play in the urinary system?

    <p>It influences sodium reabsorption.</p> Signup and view all the answers

    Which process allows water to pass through cell membranes based on concentration gradients?

    <p>Osmosis</p> Signup and view all the answers

    What is the end product of the filtration and reabsorption processes in the nephron?

    <p>Urine</p> Signup and view all the answers

    What influences water reabsorption in the collecting duct?

    <p>Antidiuretic hormone (ADH)</p> Signup and view all the answers

    What is the primary component of macroscopic urine analysis?

    <p>Color and clarity</p> Signup and view all the answers

    Which of these mechanisms describes the movement of particles from an area of high concentration to an area of low concentration?

    <p>Diffusion</p> Signup and view all the answers

    Study Notes

    Altered Elimination Module 1

    • Elimination processes are vital for maintaining homeostasis by removing waste products from the body.
    • This module reviews the impact of altered urinary and gastrointestinal processes.
    • A YouTube video link is provided for further information: https://www.youtube.com/watch?v=QV1Y
    • The renal system is crucial for managing body fluid balance, blood pressure, and eliminating metabolic waste.
    • The renal system produces erythropoietin for red blood cell production, renin for fluid and blood pressure balance, and vitamin D for calcium absorption.
    • A YouTube video link is provided for further renal system information; https://www.youtube.com/watch?v=H2VkW9L5QSU (6.)

    Renal System

    • The nephron is the functional unit of the kidneys.
    • It filters water-soluble substances, reabsorbs nutrients and water, and secretes wastes.
    • A YouTube video link is provided: https://www.youtube.com/watch?v=SZ3BZ_
    • Blood enters the kidneys through the renal artery, which branches into smaller arterioles.
    • Blood then flows into the glomerular capillaries (glomerulus) where pressure forces a filtrate into the Bowman's capsule.
    • The filtrate contains water, ions, glucose, and small proteins.
    • The proximal tubule absorbs sodium and other ions back into the bloodstream.
    • Filtrate passes through the loop of Henle, where further water and sodium are absorbed.
    • The distal tubule further adjusts the electrolyte composition of the filtrate, secreting ions and wastes.

    Urine Production

    • Water, ions, glucose, and small proteins are filtered from the blood in the glomerulus.
    • The proximal tubule absorbs valuable substances.
    • The loop of Henle absorbs more water and sodium.
    • The distal tubule, controlled by hormones like aldosterone and ADH, adjusts ion concentration and excretes waste.
    • The filtrate is collected in the collecting ducts and finally becomes urine expelled from the body.

    Filtration

    • Filtrate composition includes water, ions (sodium, potassium, chloride), glucose, and small proteins.
    • Substances are reabsorbed or secreted in different parts of the nephron, including the proximal tubule, loop of Henle and distal tubule.
    • A diagram depicts the process of filtration.

    Urine Production Overview

    • The process involves the Bowman's capsule, glomerulus, proximal tubule, loop of Henle, distal tubule, and collecting duct.
    • Water and solutes are reabsorbed or secreted depending on the specific location in the nephron.
    • Various substances are reabsorbed or secreted along the process.
    • ADH plays a significant role in controlling water reabsorption.
    • Specialized blood vessels called the vasa recta facilitate efficient transport of water and substances.

    Filtrate Absorption

    • Diffusion, osmosis, facilitated transport, and active transport are the mechanisms used by the nephrons to reabsorb substances.
    • Diffusion moves particles from an area of high concentration to one of low concentration.
    • Osmosis moves water from high to low concentration.
    • Facilitated transport utilizes specialized proteins to facilitate the movement of substances across cell membranes..
    • Active transport requires energy to move particles across cell membranes.

    Urine Production

    • The majority of sodium is absorbed in the proximal convoluted loop.
    • Glucose, potassium, amino acids, bicarbonate, phosphate, urea, and water are also reabsorbed (in the proximal convoluted loop)
    • Water is reabsorbed, and sodium actively reabsorbed.
    • In the distal tube, ions, acids, medications, and toxins (such as K+, urea, and ammonia) are secreted. Some ion and water absorption occurs.

    Urine Production (Distal Convoluted Loop)

    • Aldosterone regulates sodium reabsorption.
    • Potassium, urea, hydrogen ions, and ammonia are secreted into the filtrate.
    • Antidiuretic hormone (ADH) controls water reabsorption.
    • The final product is urine.

    Urine Production (Macroscopic Analysis)

    • Urine is typically light yellow in color.
    • The pH ranges from 4.6-8.0.
    • Specific gravity is 1.005-1.030.
    • Proteins are less than 0.15g/day.
    • Red blood cells (RBCs) and white blood cells (WBCs) are typically 0-4 and 0-5/hpf respectively.
    • Occasionally, casts (formed from proteins and cells) may be present.

    Urine Analysis: Abnormal Findings

    • Elevated protein levels (>0.15g/day) may indicate impaired filtration.
    • Glucose presence suggests hyperglycemia or infection.
    • Elevated ketones may indicate an acid-base imbalance or diabetes.
    • Leukocytes presence may indicate an infection.
    • Nitrites presence suggests an infection.

    Lab and Kidney Function

    • Blood urea nitrogen (BUN) is a measure of urea from protein metabolism. Normal range is 3.6 to 7.1 mmol/L.
    • Creatinine is a waste product from muscle metabolism. Normal range is 53 to 103 μmol/L.
    • Potassium is an electrolyte mostly excreted by the kidneys. Normal range is 3.5 to 5 mmol/L.
    • Glomerular filtration rate (GFR) is the rate at which blood is filtered by the glomeruli; normal values are >90 mL/min/1.73 m².

    Urine Removal

    • Urine from the kidneys travels through the ureters to the bladder.
    • Peristalsis propels urine through the ureters.
    • The trigone, located in the bladder, is sensitive to stretch, triggering the need to urinate.
    • Messages are sent to the brain, signaling urination.

    Micturition Reflex

    • Stimulation of stretch receptors in the bladder sends impulses to the sacral spinal cord.
    • Impulses travel to the pons and to the spinal detrusor muscles.
    • Internal sphincter relaxation and external sphincter relaxation lead to urine release.

    Incontinence and Retention

    • Loss of voluntary bladder control = incontinence.
    • Increased intra-abdominal pressure causes stress incontinence (laughing, coughing).
    • Spinal cord injury or brain damage can disrupt the micturition reflex, causing retention or incontinence.
    • Catheters can be used to drain urine.

    Categorization of Urinary Track Problems

    • Pre-renal, intra-renal, and post-renal problems are categorized.
    • Kidney failure can be a result of these conditions.

    Glomerulonephritis

    • Glomerulonephritis is inflammation of the glomeruli.
    • It can be acute or chronic, and it can be associated with other diseases (lupus, diabetes).
    • Inflammation in the glomeruli can damage the kidneys.

    Altered Urinary Neuromuscular Function

    • Altered function can lead to urinary retention or incontinence.
    • Spinal cord injuries may affect neural impulses that control urination.
    • The level of the injury influences the impact and urinary function.

    Alteration in Urinary Motility

    • Fluid intake impacts urine output.
    • Urine stasis can lead to infection.
    • Stasis occurs with slow nephron movement or bladder retention of the filtrate.

    Alteration in Urinary Perfusion

    • The kidneys filter 1 liter of blood per minute.
    • Decreased blood flow negatively impacts kidney function resulting in reduced filtration and toxicity.
    • Elevated levels of blood urea nitrogen (BUN) and creatinine indicate reduced kidney function.
    • High blood pressure is a significant cause of kidney damage.

    Acute Kidney Failure

    • Acute kidney failure is the inability of the kidneys to remove waste effectively.
    • Characterized by rapid accumulation of waste products (azotemia) and reduced urine output (oliguria <500mL/24hrs.).
    • Causes include hemorrhage, trauma, infection (such as pyelonephritis or glomerulonephritis)

    Acute Kidney Failure Nursing Interventions

    • Initially, fluid restriction to 1L/day is implemented.
    • Intake and output are closely monitored, and daily weights are recorded.
    • Low potassium diets are prescribed.
    • Closely monitoring electrolytes, BUN, creatinine, and GFR are important. -Rehydration may be provided once GFR improves. -The role of youtube videos is mentioned.

    Alteration of Urinary Patency

    • Blockage or obstructions in the urinary tract disrupt urine flow, potentially damaging nephrons.
    • Blockages may be caused by substances (stones) or external sources (tumors).
    • Urine backing up into the kidneys creates a condition known as hydronephrosis.
    • Urine stasis can lead to infection.

    Urolithiasis (Kidney Stones)

    • Urolithiasis is the presence of kidney stones.
    • Calculi are solid masses, often composed of salts, or organic acids precipitating from the filtrate.
    • Calcium, oxalate, and phosphate constitute most kidney stones.
    • Kidney stones can form due to elevated calcium levels combining with oxalate or phosphate, creating stones, that are slowly increase in size.
    • Sudden flank pain and microscopic blood in the urine indicate possible stones.

    Urolithiasis (Kidney Stones) Risk Factors

    • Genetic predisposition plays a significant role in kidney stone formation.
    • Urinary tract infections increase susceptibility to kidney stones.
    • Diabetes, obesity, and hyperparathyroidism are additional factors.
    • High oxalate intake, high animal protein, and high sodium intake contribute to kidney stone development (while low fluid intake hinders stone dissolution).

    Urolithiasis (Kidney Stones) Non Surgical Treatment

    • Pain management techniques, fluids (non-caffeinated beverages), and antispasmodic medications are employed.
    • Urine straining helps identify stones.
    • Dietary modifications (reducing stone risk factors) and increased hydration are advocated.
    • Decreasing caffeine and foods with oxalates aids in reducing the risks of stones.

    Urolithiasis (Kidney Stones) Surgical Treatment

    • Extracorporeal shockwave lithotripsy (ESWL) uses shock waves to break stones into smaller pieces.
    • Ureteroscopes are used to retrieve or fragment stones in the ureters.
    • Placement of a stent may be necessary after procedures.
    • The importance of post-procedural nursing care is highlighted, including vital signs monitoring, IV fluids, intake and output management, pain management.

    Learning Objectives

    • Understanding kidney structure and functions, nephron structure and function (proximal tubule, loop of Henle, distal tubule)
    • Defining filtrate and its components.
    • Understanding bladder structure and function.
    • Understanding the micturition reflex.
    • Recognizing normal and abnormal urine content. Describing the processes of acute kidney failure, urolithiasis, and altered urinary motility, along with relevant nursing interventions.

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