Podcast
Questions and Answers
What is the drug class for sitagliptin?
What is the drug class for sitagliptin?
What are the key drugs for sitagliptin?
What are the key drugs for sitagliptin?
Tapazol, Januvia
What is the mechanism of action for sitagliptin?
What is the mechanism of action for sitagliptin?
Inhibits enzyme DPP-4
Which of the following are adverse reactions to sitagliptin? (Select all that apply)
Which of the following are adverse reactions to sitagliptin? (Select all that apply)
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What is the pharmacokinetics (PK) profile for sitagliptin?
What is the pharmacokinetics (PK) profile for sitagliptin?
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Which substances may interact with sitagliptin? (Select all that apply)
Which substances may interact with sitagliptin? (Select all that apply)
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What nursing care should be taken when administering sitagliptin?
What nursing care should be taken when administering sitagliptin?
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Sitagliptin is prescribed for what condition?
Sitagliptin is prescribed for what condition?
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Study Notes
Sitagliptin Overview
- Sitagliptin is classified as an antidiabetic medication, specifically an enzyme inhibitor known as a gliptin.
Key Medications
- Commonly associated drugs include Tapazol and Januvia.
Mechanism of Action
- Functions by inhibiting the enzyme DPP-4 (Dipeptidyl Peptidase-4), which plays a role in glucose metabolism.
Adverse Reactions
- Potential side effects include:
- Headache
- Pancreatitis
- Nausea
- Diarrhea
- Acute renal failure
- Upper respiratory tract infections
- Nasopharyngitis
- Stevens-Johnson syndrome
- Rash and urticaria
Pharmacokinetics
- About 79% of sitagliptin is excreted unchanged in urine.
- Undergoes minor metabolism and shows an absorption rate of 87% following oral administration.
Drug Interactions
- Can increase serum levels of other medications, specifically:
- Digoxin
- Insulin
- Glyburide
- Glipizide
- Glimepiride
Nursing Considerations
- Monitor patients for signs of hypoglycemia, pancreatitis, and any skin rashes.
Indications for Use
- Primarily prescribed for the management of Type II diabetes.
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Description
Test your knowledge about sitagliptin, a medication used in diabetes treatment. These flashcards cover its drug class, key drugs, mechanisms of action, and potential adverse reactions. Ideal for pharmacy students and healthcare professionals.
