Sickle Cell Hemoglobin

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Questions and Answers

What is the consequence of the amino acid substitution in sickle-cell anemia?

  • Increased number of hemoglobin molecules
  • Deformation of red blood cells
  • Clotting in blood vessels and tissues
  • All of the above (correct)

What happens to the hemoglobin molecules in sickle-cell anemia?

  • They become more soluble in water
  • They clump together and form aggregates (correct)
  • They are destroyed by the immune system
  • They become smaller in size

Which amino acid substitution is responsible for sickle-cell anemia?

  • Asp to Val
  • Glu to Val (correct)
  • Glu to Asn
  • Asp to Asn

What causes the change in shape of red blood cells in sickle-cell anemia?

<p>Mutation in DNA sequence (D)</p> Signup and view all the answers

What is one of the consequences of sickle-cell anemia?

<p>Decreased lifespan of red blood cells (A)</p> Signup and view all the answers

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