Sickle Cell Disease Quiz

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Questions and Answers

What replaces normal hemoglobin in the red blood cells of individuals with sickle cell disease?

  • Hemoglobin A
  • Hemoglobin F
  • Abnormal hemoglobin SS (correct)
  • Normal hemoglobin

What can sickled cells adhere to, leading to obstruction of blood flow?

  • Veins only
  • Capillary walls and each other (correct)
  • Arterial walls only
  • Lymphatic vessels

What happens to the lifespan of sickled cells compared to normal red blood cells?

  • Decreased lifespan due to sickling (correct)
  • No change in lifespan
  • Lifespan becomes indefinite
  • Increased lifespan due to sickling

What does sickle cell crisis cause in individuals with sickle cell anemia?

<p>Microinfarcts in joints and organs (C)</p> Signup and view all the answers

What can resume a normal shape when rehydrated or reoxygenated?

<p>Sickle cells (B)</p> Signup and view all the answers

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Study Notes

Sickle Cell Disease

  • Hemoglobin S (HbS) replaces normal hemoglobin in the red blood cells of individuals with sickle cell disease.

Sickle Cell Characteristics

  • Sickle cells can adhere to the endothelium, leading to obstruction of blood flow.

Red Blood Cell Lifespan

  • The lifespan of sickled cells is shorter compared to normal red blood cells.

Sickle Cell Crisis

  • Sickle cell crisis causes severe pain, damage to organs, and even death in individuals with sickle cell anemia.

Reversibility of Sickle Cells

  • Sickle cells can resume a normal shape when rehydrated or reoxygenated.

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