5 Questions
What replaces normal hemoglobin in the red blood cells of individuals with sickle cell disease?
Abnormal hemoglobin SS
What can sickled cells adhere to, leading to obstruction of blood flow?
Capillary walls and each other
What happens to the lifespan of sickled cells compared to normal red blood cells?
Decreased lifespan due to sickling
What does sickle cell crisis cause in individuals with sickle cell anemia?
Microinfarcts in joints and organs
What can resume a normal shape when rehydrated or reoxygenated?
Sickle cells
Study Notes
Sickle Cell Disease
- Hemoglobin S (HbS) replaces normal hemoglobin in the red blood cells of individuals with sickle cell disease.
Sickle Cell Characteristics
- Sickle cells can adhere to the endothelium, leading to obstruction of blood flow.
Red Blood Cell Lifespan
- The lifespan of sickled cells is shorter compared to normal red blood cells.
Sickle Cell Crisis
- Sickle cell crisis causes severe pain, damage to organs, and even death in individuals with sickle cell anemia.
Reversibility of Sickle Cells
- Sickle cells can resume a normal shape when rehydrated or reoxygenated.
Test your knowledge of sickle cell disease with this quiz! Explore the disease process, symptoms, and complications associated with this hereditary blood disorder.
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