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Questions and Answers
What replaces normal hemoglobin in the red blood cells of individuals with sickle cell disease?
What replaces normal hemoglobin in the red blood cells of individuals with sickle cell disease?
- Hemoglobin A
- Hemoglobin F
- Abnormal hemoglobin SS (correct)
- Normal hemoglobin
What can sickled cells adhere to, leading to obstruction of blood flow?
What can sickled cells adhere to, leading to obstruction of blood flow?
- Veins only
- Capillary walls and each other (correct)
- Arterial walls only
- Lymphatic vessels
What happens to the lifespan of sickled cells compared to normal red blood cells?
What happens to the lifespan of sickled cells compared to normal red blood cells?
- Decreased lifespan due to sickling (correct)
- No change in lifespan
- Lifespan becomes indefinite
- Increased lifespan due to sickling
What does sickle cell crisis cause in individuals with sickle cell anemia?
What does sickle cell crisis cause in individuals with sickle cell anemia?
What can resume a normal shape when rehydrated or reoxygenated?
What can resume a normal shape when rehydrated or reoxygenated?
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Study Notes
Sickle Cell Disease
- Hemoglobin S (HbS) replaces normal hemoglobin in the red blood cells of individuals with sickle cell disease.
Sickle Cell Characteristics
- Sickle cells can adhere to the endothelium, leading to obstruction of blood flow.
Red Blood Cell Lifespan
- The lifespan of sickled cells is shorter compared to normal red blood cells.
Sickle Cell Crisis
- Sickle cell crisis causes severe pain, damage to organs, and even death in individuals with sickle cell anemia.
Reversibility of Sickle Cells
- Sickle cells can resume a normal shape when rehydrated or reoxygenated.
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