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Questions and Answers
What is the characteristic shape of red blood cells in sickle cell disorders?
What is the characteristic shape of red blood cells in sickle cell disorders?
- Sickle shape (correct)
- Biconcave disc shape
- Spherical shape
- Hexagonal shape
What is the severe form of sickle cell disorder known as?
What is the severe form of sickle cell disorder known as?
- Sickle cell anaemia (correct)
- Sickle cell thalassemia
- Sickle cell trait
- HbSC disorder
Which type of sickle cell disorder is the heterozygous form of Hb S known as?
Which type of sickle cell disorder is the heterozygous form of Hb S known as?
- HbSD disorder
- Sickle cell thalassemia
- Sickle cell trait (correct)
- HbSC disorder
Who provided the first written account of sickle cell disease in 1874?
Who provided the first written account of sickle cell disease in 1874?
In which year was the first case of sickle cell disease reported by Drs James Herrick and Ernest Irons?
In which year was the first case of sickle cell disease reported by Drs James Herrick and Ernest Irons?
What is the state in which red cells exposed to deoxygenation polymerize and deform into a sickle shape called?
What is the state in which red cells exposed to deoxygenation polymerize and deform into a sickle shape called?
What did Linus Pauling and colleagues demonstrate in 1949?
What did Linus Pauling and colleagues demonstrate in 1949?
In what region is Sickle cell anaemia more prevalent?
In what region is Sickle cell anaemia more prevalent?
What did Dr. Alan Raper suggest in 1949?
What did Dr. Alan Raper suggest in 1949?
What is the estimated carrier rate of Sickle cell disease in Nigeria?
What is the estimated carrier rate of Sickle cell disease in Nigeria?
What is the mechanism proposed for the overt protection enjoyed in the carrier state of Sickle cell disease?
What is the mechanism proposed for the overt protection enjoyed in the carrier state of Sickle cell disease?
What did Hahn and Gillespie show in 1927?
What did Hahn and Gillespie show in 1927?
Where is Hb C most prevalent?
Where is Hb C most prevalent?
What did Sydenstricker and Huck note in 1923?
What did Sydenstricker and Huck note in 1923?
What was demonstrated by Hunt and Ingram in the late 1950s?
What was demonstrated by Hunt and Ingram in the late 1950s?
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