Sickle Cell Disease Monitoring and Treatment Quiz
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Questions and Answers

What is a common finding in individuals with severe anemia?

  • Tinnitus
  • Atrophic glossitis (correct)
  • Tachycardia
  • Cheilitis

Which symptom is not typically associated with anemia?

  • Sore tongue and mouth
  • Restlessness (correct)
  • Pica and pagophagia
  • Skin pallor

What can be a sign of anemia in nails?

  • Concave shape (correct)
  • Ridges on the surface
  • Brittle texture
  • Reddish color

What is a common CNS-related symptom of anemia?

<p>Dizziness (A)</p> Signup and view all the answers

Which system's ability affects the clinical presentation of anemia?

<p>Cardiovascular system (C)</p> Signup and view all the answers

What is a GI-related symptom often seen in individuals with anemia?

<p>GI bleeding (D)</p> Signup and view all the answers

What is the average incubation period for HCV?

<p>Six to seven weeks (D)</p> Signup and view all the answers

Which virus has signs and symptoms often undistinguishable from those of HCV?

<p>Hepatitis A virus (HAV) (C)</p> Signup and view all the answers

What percentage of clients infected with genotype 1 achieve a sustained virologic response (SVR)?

<p>Approximately 50% (D)</p> Signup and view all the answers

Which factor does NOT increase the risk of developing chronic hepatitis and its complications?

<p>Female gender (C)</p> Signup and view all the answers

What is the major feature of HCV according to the text?

<p>Insidious onset (B)</p> Signup and view all the answers

What percentage of clients develop cirrhosis due to HCV infection?

<p>Around 20% (C)</p> Signup and view all the answers

What is the recommended follow-up diagnostic test for Iron deficiency anemia (IDA) if indicated?

<p>Serum TIBC and serum ferritin (C)</p> Signup and view all the answers

Which diagnostic test is NOT recommended for investigating Iron deficiency anemia (IDA)?

<p>Urinalysis (D)</p> Signup and view all the answers

What does an absent iron storage indicate in terms of serum iron concentration?

<p>Serum ferritin value &lt;30 ng/mL (B)</p> Signup and view all the answers

Which condition is NOT included in the differential diagnosis of Iron deficiency anemia (IDA)?

<p>Hemochromatosis (A)</p> Signup and view all the answers

How long should treatment for Iron deficiency anemia (IDA) continue after the Hematocrit (Hct) returns to normal?

<p>At least 4 to 6 months (D)</p> Signup and view all the answers

Which diagnostic test is specifically mentioned for evaluating adults with a new diagnosis of Iron deficiency anemia (IDA) and no obvious source of blood loss?

<p>Upper endoscopy (B)</p> Signup and view all the answers

What is the characteristic feature of microcytic anaemia?

<p>Small, pale red blood cells (D)</p> Signup and view all the answers

In males, what are the typical levels of haemoglobin and haematocrit in microcytic anaemia?

<p>Hgb &lt;130 g/L and Hct &lt;41% (A)</p> Signup and view all the answers

Which population group is iron deficiency anaemia particularly prevalent in?

<p>Women of childbearing age (A)</p> Signup and view all the answers

What is the estimated occurrence of iron deficiency in adult women in the United States?

<p>20% (A)</p> Signup and view all the answers

How does the pathogenesis of iron deficiency anaemia progress?

<p>Iron loss exceeds intake leading to stored iron depletion (C)</p> Signup and view all the answers

Which test is recommended to screen for retinopathy annually starting from 8 years old?

<p>'Retinal examinations' (A)</p> Signup and view all the answers

What is the main consequence of transferrin deficiency?

<p>Accumulation of iron in tissues (C)</p> Signup and view all the answers

In ceruloplasmin deficiency, what is the role of ferroxidase?

<p>Converts Fe2+ to Fe3+ for binding to transferrin (C)</p> Signup and view all the answers

What is the key mechanism for iron overload in both HFE and non-HFE hemochromatosis?

<p>Enhanced iron absorption from the gastrointestinal tract (B)</p> Signup and view all the answers

What is the normal total body iron content in men?

<p>3.5 g (A)</p> Signup and view all the answers

Why are clinical manifestations of hemochromatosis uncommon before menopause in women?

<p>Reduced iron loss due to menses (D)</p> Signup and view all the answers

What is the critical control mechanism for iron absorption?

<p>Hepcidin (B)</p> Signup and view all the answers

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