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Questions and Answers
What is the reason that genetically modified tumor cells injected at the primary site are not effective in screening for metastasis?
What is the reason that genetically modified tumor cells injected at the primary site are not effective in screening for metastasis?
- The throughput of screens is too high
- The process of metastasis is highly selective (correct)
- The genetic alterations necessary for metastasis are acquired by all cancer cells
- The process of metastasis is not complex enough
What is required for the completion of each step of metastasis?
What is required for the completion of each step of metastasis?
- The mutation of a single gene
- The destruction of multiple capabilities
- The acquisition of multiple capabilities (correct)
- The inhibition of multiple capabilities
Why have gain-of-function screens not been successfully applied to metastasis?
Why have gain-of-function screens not been successfully applied to metastasis?
- Metastasis is a highly complex process (correct)
- Gain-of-function screens are not effective for any type of cancer
- There is only one gene involved in metastasis
- Metastasis is a simple process
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