5 Questions
Which condition is NOT associated with elevated serum ALT activity?
Acute Myocardial Infarction
Which condition does NOT cause elevated serum AST levels?
Obstructive jaundice
Which condition specifically causes AST levels to rise within 6 to 8 hours, peak at 24 hours, and return to normal within 5 days?
Acute Myocardial Infarction
Which condition associated with liver damage is NOT a primary cause of elevated serum ALT levels?
Drug toxicity
Which of the following conditions is indicative of tissue necrosis resulting in a significant rise in AST levels?
Necrosis of liver tissue
Study Notes
Serum Elevation of ALT Activity
- Serum elevation of ALT activity is observed in parenchymal liver diseases such as:
- Cirrhosis
- Carcinoma
- Hepatitis
- Obstructive jaundice
- Alcohol consumption
Serum Elevation of AST Activity
- AST is normally present in blood at low levels
- AST is released into the bloodstream when any of its tissues are damaged
- Increased AST levels are indicative of a tissue injury, but not specific to the liver
- Serum AST is greatly increased in cases of:
- Myopathy
- Hepatitis and hemolytic anemia
- Damage to the liver from drugs or other toxic substances
- A blockage in blood flow to the liver
- In Acute Myocardial Infarction (AMI):
- AST levels begin to rise within 6-8 hours
- AST levels peak at 24 hours
- AST levels generally return to normal within 5 days
This quiz covers the medical conditions that cause serum elevation of ALT activity, including cirrhosis, carcinoma, hepatitis, obstructive jaundice, and alcohol consumption. It also compares ALT and AST levels in the bloodstream.
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