Serotonin and Mood Disorders
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Questions and Answers

Which part of the nervous system is responsible for the release of acetylcholine at the neuromuscular junction?

  • Central nervous system
  • Somatic nervous system
  • Autonomic nervous system
  • Peripheral nervous system (correct)

What is the role of acetylcholine in the central nervous system?

  • Initiation of REM sleep (correct)
  • Coordination of skeletal muscle contraction
  • Planning of movement
  • Regulation of heart rate

Which receptors are stimulated by nicotine and blocked by curare?

  • Muscarinic acetylcholine metabotropic receptors
  • Serotonin receptors
  • Dopamine receptors
  • Nicotinic acetylcholine ionotropic receptors (correct)

Which neurotransmitter is synthesized from L-DOPA?

<p>Dopamine (B)</p> Signup and view all the answers

Which dopamine system plays a major role in movement, particularly in the initiation of voluntary movements?

<p>Nigrostriatal system (A)</p> Signup and view all the answers

Which dopamine system is involved in reward and reinforcement?

<p>Mesolimbic system (B)</p> Signup and view all the answers

Which dopamine system plays a role in high-level cognitive processes such as attention and working memory?

<p>Mesocortical system (C)</p> Signup and view all the answers

Which neurotransmitter is the primary inhibitory neurotransmitter?

<p>GABA (B)</p> Signup and view all the answers

What happens when there is too much glutamate in the brain?

<p>Seizures, excitotoxicity, and brain death (D)</p> Signup and view all the answers

Which receptors control a sodium (Na+) channel?

<p>AMPA receptors (C)</p> Signup and view all the answers

What is the role of NMDA receptors in increasing synaptic connection strength?

<p>They let in Cu+ ions that build new AMPA receptors (C)</p> Signup and view all the answers

Which of the following is true about Long-Term Depression (LTD)?

<p>LTD weakens synaptic strength (B)</p> Signup and view all the answers

What happens when knowledge learned in a semester is not regularly used?

<p>Synaptic strength weakens (D)</p> Signup and view all the answers

Which of the following is true about benzodiazepines (benzos)?

<p>Benzos act as an indirect agonist of GABA (A)</p> Signup and view all the answers

What happens when a person addicted to inhibitory drugs such as benzos stops taking them?

<p>Withdrawal symptoms occur due to imbalanced neurotransmitter levels (B)</p> Signup and view all the answers

Which neurotransmitter is primarily responsible for mood regulation in the brain?

<p>Serotonin (D)</p> Signup and view all the answers

Which class of antidepressants selectively agonizes serotonin and is as effective as tricyclic antidepressants and monoamine oxidase inhibitors, but with fewer side effects?

<p>Selective serotonin reuptake inhibitors (D)</p> Signup and view all the answers

Which drug inhibits the reuptake of serotonin, thereby increasing the availability of serotonin in the synapses?

<p>Fluoxetine (D)</p> Signup and view all the answers

Which class of antidepressants non-selectively agonizes the entire monoamine family, including serotonin, and has a high effectiveness equal to modern antidepressants but with more side effects?

<p>Monoamine oxidase inhibitors (A)</p> Signup and view all the answers

Which of the following is true about dopaminergic drugs and their effects on Parkinson's disease patients?

<p>Dopaminergic drugs cause strange behaviors such as pleasure-seeking, cognitive problems, and psychosis in Parkinson's disease patients. (A)</p> Signup and view all the answers

Which of the following correctly describes the effect of dopamine agonists on the nigrostriatal system?

<p>Dopamine agonists cause hyperactivity by overstimulating the nigrostriatal system. (D)</p> Signup and view all the answers

Which of the following is a dopamine antagonist used in the treatment of schizophrenia?

<p>Chlorpromazine (D)</p> Signup and view all the answers

Which of the following correctly describes the role of norepinephrine and epinephrine?

<p>Norepinephrine and epinephrine act as neurotransmitters in the brain and hormones in the body. (D)</p> Signup and view all the answers

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