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Questions and Answers
What is the estimated number of people with asthma in 2025?
What is the estimated number of people with asthma in 2025?
What is the incidence of physician-diagnosed asthma in Saudi Arabia from the total population?
What is the incidence of physician-diagnosed asthma in Saudi Arabia from the total population?
Who had 1.8 times greater asthma incidence in Saudi Arabia, adult females or adult males?
Who had 1.8 times greater asthma incidence in Saudi Arabia, adult females or adult males?
How many deaths occur due to asthma every year?
How many deaths occur due to asthma every year?
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What is the range of asthma incidence rates for children diagnosed by physicians in Saudi Arabia?
What is the range of asthma incidence rates for children diagnosed by physicians in Saudi Arabia?
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Where can the GINA MAIN report be linked according to the text?
Where can the GINA MAIN report be linked according to the text?
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What percentage of patients achieved total control as defined by GINA guidelines with SFC?
What percentage of patients achieved total control as defined by GINA guidelines with SFC?
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How much more symptom-free days does Seroflo offer than BUD/FOR over 58 weeks?
How much more symptom-free days does Seroflo offer than BUD/FOR over 58 weeks?
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By what percentage does Seroflo reduce the need for oral corticosteroids more than BUD/FOR?
By what percentage does Seroflo reduce the need for oral corticosteroids more than BUD/FOR?
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What percentage of patients achieved GINA guideline-defined well-controlled asthma with SFC?
What percentage of patients achieved GINA guideline-defined well-controlled asthma with SFC?
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By what percentage does Seroflo reduce hospitalization more than BUD/FOR?
By what percentage does Seroflo reduce hospitalization more than BUD/FOR?
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What percentage of patients experienced improved lung function over 1 year with SFC?
What percentage of patients experienced improved lung function over 1 year with SFC?
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What is the recommended dosage of salmeterol and fluticasone propionate for adults and adolescents?
What is the recommended dosage of salmeterol and fluticasone propionate for adults and adolescents?
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At what age is the use of Seroflo Inhaler not recommended?
At what age is the use of Seroflo Inhaler not recommended?
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What is the Seroflo Inhaler indicated for?
What is the Seroflo Inhaler indicated for?
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What health conditions require precautions when using the Seroflo Inhaler?
What health conditions require precautions when using the Seroflo Inhaler?
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When is the use of a spacer device with the Seroflo Inhaler recommended?
When is the use of a spacer device with the Seroflo Inhaler recommended?
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Why is regular cleaning of the Seroflo Inhaler necessary?
Why is regular cleaning of the Seroflo Inhaler necessary?
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Who is Seroflo Ciphaler recommended for with one inhalation twice a day?
Who is Seroflo Ciphaler recommended for with one inhalation twice a day?
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What is the recommended dosage for adults with COPD?
What is the recommended dosage for adults with COPD?
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Who is Seroflo Ciphaler indicated for regarding asthma?
Who is Seroflo Ciphaler indicated for regarding asthma?
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What should healthcare professionals do regarding the usage of Seroflo Ciphaler?
What should healthcare professionals do regarding the usage of Seroflo Ciphaler?
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What should caregivers ensure when children use Seroflo Ciphaler?
What should caregivers ensure when children use Seroflo Ciphaler?
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What is recommended for cleaning the mouthpiece of the inhaler?
What is recommended for cleaning the mouthpiece of the inhaler?
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What is the mechanism of action of Seroflo in treating asthma?
What is the mechanism of action of Seroflo in treating asthma?
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What is the primary purpose of Seroflo in asthma management?
What is the primary purpose of Seroflo in asthma management?
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What was the design of the 1-year study involving 3,421 patients with uncontrolled asthma?
What was the design of the 1-year study involving 3,421 patients with uncontrolled asthma?
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What is the purpose of the concept study assessing the effectiveness of Seroflo in adult patients with symptomatic asthma not controlled by existing therapy?
What is the purpose of the concept study assessing the effectiveness of Seroflo in adult patients with symptomatic asthma not controlled by existing therapy?
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What feature does the device used for Seroflo, Ciphaler, have to ensure compliance?
What feature does the device used for Seroflo, Ciphaler, have to ensure compliance?
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What do the GINA guidelines provide specific recommendations for?
What do the GINA guidelines provide specific recommendations for?
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Study Notes
Seroflo Asthma Medication Overview
- Seroflo is indicated for the regular treatment of asthma in patients aged 12 and above, particularly for uncontrolled asthmatic patients starting from step 3.
- It is also used as maintenance treatment for well-controlled or partially controlled asthmatic patients.
- The mechanism of action involves the synthetic corticosteroid fluticasone propionate, which has anti-inflammatory activity mediated via glucocorticoid receptors and inhibition of cytokine formation.
- Additionally, it contains a highly selective β2-adrenoceptor (LABA) agonist, salmeterol, which provides long-acting bronchodilator activity through the relaxation of bronchial smooth muscle.
- Seroflo aims to improve patients' lives and achieve total control as defined by GINA guidelines, as well as improve lung function to enable engagement in everyday activities without limitations.
- A 1-year study involving 3,421 patients with uncontrolled asthma compared fluticasone propionate and salmeterol/fluticasone in achieving guideline-based measures of control, with treatment stepped up until total control was achieved.
- The study design included a stratified, randomized, double-blind, parallel-group study, with the largest number of patients ever recruited in a trial on asthma.
- Another concept study aimed to assess the effectiveness of Seroflo in adult patients with symptomatic asthma not controlled by existing therapy, involving a 52-week double-blind treatment period and a 2-week follow-up period.
- The double-blind treatment period involved two phases, the first maintaining a constant dose delivered from both devices, and the second adjusting the dose delivered via Turbuhaler according to physician guidance.
- The device used for Seroflo, Ciphaler, ensures high compliance and dose delivery, with a well-known inhaler design and the addition of a dose counter to ensure compliance.
- Seroflo's benefits include improving patients' lives, helping them lead healthier, happier, and more fulfilling lifestyles, achieving total control as per GINA guidelines, and improving lung function to enable engagement in everyday activities without limitations.
- The GINA guidelines provide specific recommendations for asthma management in children and adults, including the use of anti-inflammatory reliever (AIR) and guidelines for asthma severity and control assessment.
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Description
Test your knowledge about Seroflo, a medication for asthma management in patients aged 12 and above. Learn about its mechanism of action, clinical studies, device, and benefits in achieving total control as per GINA guidelines.