Seroflo Quiz

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Questions and Answers

What is the estimated number of people with asthma in 2025?

200 million

300 million

100 million (correct)

400 million

What is the incidence of physician-diagnosed asthma in Saudi Arabia from the total population?

11.3% (correct)

57%

33.7%

Who had 1.8 times greater asthma incidence in Saudi Arabia, adult females or adult males?

Adult males

Both had the same incidence

Children had the highest incidence

Adult females (correct)

How many deaths occur due to asthma every year?

250,000 Signup and view all the answers

What is the range of asthma incidence rates for children diagnosed by physicians in Saudi Arabia?

4%–33.7% Signup and view all the answers

Where can the GINA MAIN report be linked according to the text?

2023 GINA MAIN report Signup and view all the answers

What percentage of patients achieved total control as defined by GINA guidelines with SFC?

31% Signup and view all the answers

How much more symptom-free days does Seroflo offer than BUD/FOR over 58 weeks?

23% Signup and view all the answers

By what percentage does Seroflo reduce the need for oral corticosteroids more than BUD/FOR?

30% Signup and view all the answers

What percentage of patients achieved GINA guideline-defined well-controlled asthma with SFC?

63% Signup and view all the answers

By what percentage does Seroflo reduce hospitalization more than BUD/FOR?

20% Signup and view all the answers

What percentage of patients experienced improved lung function over 1 year with SFC?

58% Signup and view all the answers

What is the recommended dosage of salmeterol and fluticasone propionate for adults and adolescents?

25mcg salmeterol and 125mcg fluticasone propionate twice daily Signup and view all the answers

At what age is the use of Seroflo Inhaler not recommended?

Under 12 years of age Signup and view all the answers

What is the Seroflo Inhaler indicated for?

Regular asthma treatment Signup and view all the answers

What health conditions require precautions when using the Seroflo Inhaler?

Heart disease and diabetes Signup and view all the answers

When is the use of a spacer device with the Seroflo Inhaler recommended?

If difficulty arises in using the inhaler Signup and view all the answers

Why is regular cleaning of the Seroflo Inhaler necessary?

To prevent blockage and ensure proper functioning Signup and view all the answers

Who is Seroflo Ciphaler recommended for with one inhalation twice a day?

Children aged 4 to 12 Signup and view all the answers

What is the recommended dosage for adults with COPD?

One inhalation twice a day of Seroflo Ciphaler 50/500 Signup and view all the answers

Who is Seroflo Ciphaler indicated for regarding asthma?

Adults and adolescents aged 12 years and over Signup and view all the answers

What should healthcare professionals do regarding the usage of Seroflo Ciphaler?

Demonstrate and monitor the correct inhalation technique Signup and view all the answers

What should caregivers ensure when children use Seroflo Ciphaler?

Follow the correct inhalation technique Signup and view all the answers

What is recommended for cleaning the mouthpiece of the inhaler?

Using a dry tissue Signup and view all the answers

What is the mechanism of action of Seroflo in treating asthma?

Activation of glucocorticoid receptors and inhibition of cytokine formation Signup and view all the answers

What is the primary purpose of Seroflo in asthma management?

Achieving total control as per GINA guidelines and improving lung function Signup and view all the answers

What was the design of the 1-year study involving 3,421 patients with uncontrolled asthma?

Stratified, randomized, double-blind, parallel-group study Signup and view all the answers

What is the purpose of the concept study assessing the effectiveness of Seroflo in adult patients with symptomatic asthma not controlled by existing therapy?

To assess the effectiveness of Seroflo in achieving total control as per GINA guidelines Signup and view all the answers

What feature does the device used for Seroflo, Ciphaler, have to ensure compliance?

A dose counter to ensure compliance Signup and view all the answers

What do the GINA guidelines provide specific recommendations for?

Asthma management in children and adults Signup and view all the answers

Study Notes

Seroflo Asthma Medication Overview

Seroflo is indicated for the regular treatment of asthma in patients aged 12 and above, particularly for uncontrolled asthmatic patients starting from step 3.
It is also used as maintenance treatment for well-controlled or partially controlled asthmatic patients.
The mechanism of action involves the synthetic corticosteroid fluticasone propionate, which has anti-inflammatory activity mediated via glucocorticoid receptors and inhibition of cytokine formation.
Additionally, it contains a highly selective β2-adrenoceptor (LABA) agonist, salmeterol, which provides long-acting bronchodilator activity through the relaxation of bronchial smooth muscle.
Seroflo aims to improve patients' lives and achieve total control as defined by GINA guidelines, as well as improve lung function to enable engagement in everyday activities without limitations.
A 1-year study involving 3,421 patients with uncontrolled asthma compared fluticasone propionate and salmeterol/fluticasone in achieving guideline-based measures of control, with treatment stepped up until total control was achieved.
The study design included a stratified, randomized, double-blind, parallel-group study, with the largest number of patients ever recruited in a trial on asthma.
Another concept study aimed to assess the effectiveness of Seroflo in adult patients with symptomatic asthma not controlled by existing therapy, involving a 52-week double-blind treatment period and a 2-week follow-up period.
The double-blind treatment period involved two phases, the first maintaining a constant dose delivered from both devices, and the second adjusting the dose delivered via Turbuhaler according to physician guidance.
The device used for Seroflo, Ciphaler, ensures high compliance and dose delivery, with a well-known inhaler design and the addition of a dose counter to ensure compliance.
Seroflo's benefits include improving patients' lives, helping them lead healthier, happier, and more fulfilling lifestyles, achieving total control as per GINA guidelines, and improving lung function to enable engagement in everyday activities without limitations.
The GINA guidelines provide specific recommendations for asthma management in children and adults, including the use of anti-inflammatory reliever (AIR) and guidelines for asthma severity and control assessment.

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Description

Test your knowledge about Seroflo, a medication for asthma management in patients aged 12 and above. Learn about its mechanism of action, clinical studies, device, and benefits in achieving total control as per GINA guidelines.