Podcast
Questions and Answers
What is the scientific term for our ability to sense pain?
What is the scientific term for our ability to sense pain?
Which receptor is responsible for sensing temperature and pain?
Which receptor is responsible for sensing temperature and pain?
Where is the TrpV1 receptor located?
Where is the TrpV1 receptor located?
How is nociception different from thermoception?
How is nociception different from thermoception?
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What are the specialized type of receptors responsible for sensing pain and temperature found in?
What are the specialized type of receptors responsible for sensing pain and temperature found in?
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What causes a conformational change in the TrpV1 protein?
What causes a conformational change in the TrpV1 protein?
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Which type of nerve fibers allows for quick signal transmission and withdrawal from painful or hot stimuli?
Which type of nerve fibers allows for quick signal transmission and withdrawal from painful or hot stimuli?
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What compound found in jalapenos induces the same response as a change in temperature when it binds to TrpV1 receptors?
What compound found in jalapenos induces the same response as a change in temperature when it binds to TrpV1 receptors?
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Where are TrpV1 receptors located in the body, including the hand?
Where are TrpV1 receptors located in the body, including the hand?
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Which type of fibers sends signals very slowly and causes a lingering sensation of pain?
Which type of fibers sends signals very slowly and causes a lingering sensation of pain?
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What is the term used to describe our ability to sense exactly where our body is in space?
What is the term used to describe our ability to sense exactly where our body is in space?
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Where do the tiny receptors responsible for proprioception originate from?
Where do the tiny receptors responsible for proprioception originate from?
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What type of sensation are the tiny receptors sensitive to?
What type of sensation are the tiny receptors sensitive to?
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What is the term for the sense of the relative position of neighboring parts of the body and strength of effort being employed in movement?
What is the term for the sense of the relative position of neighboring parts of the body and strength of effort being employed in movement?
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Which part of the body do proprioceptive receptors send feedback to?
Which part of the body do proprioceptive receptors send feedback to?
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What is the main function of proprioception?
What is the main function of proprioception?
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How is kinesthesia different from proprioception?
How is kinesthesia different from proprioception?
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What happens to the spindle sensor when a muscle is stretched?
What happens to the spindle sensor when a muscle is stretched?
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How does kinesthesia help individuals in activities like playing golf or hitting a baseball?
How does kinesthesia help individuals in activities like playing golf or hitting a baseball?
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Which term can be used to describe proprioception?
Which term can be used to describe proprioception?
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What is the function of the somatosensory homunculus?
What is the function of the somatosensory homunculus?
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Why do neurosurgeons use electrodes to touch different parts of the cortex in some cases?
Why do neurosurgeons use electrodes to touch different parts of the cortex in some cases?
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What happens if a surgeon removes a part of the cortex involved in sensation?
What happens if a surgeon removes a part of the cortex involved in sensation?
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What is the main purpose of stimulating different parts of the cortex with an electrode during surgery?
What is the main purpose of stimulating different parts of the cortex with an electrode during surgery?
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How does the sensory strip organize information from different parts of the body?
How does the sensory strip organize information from different parts of the body?
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What is the somatosensory homunculus?
What is the somatosensory homunculus?
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Where is the specialized part of the brain that receives sensory input from the entire body?
Where is the specialized part of the brain that receives sensory input from the entire body?
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What region of the brain does all sensory information from the body end up in?
What region of the brain does all sensory information from the body end up in?
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What part of the cortex is a specialized area for receiving sensory input from the entire body?
What part of the cortex is a specialized area for receiving sensory input from the entire body?
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What is the function of the somatosensory homunculus?
What is the function of the somatosensory homunculus?
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Study Notes
- The text discusses the mechanism of how temperature and pain stimuli activate the TrpV1 receptor and transmit signals to the brain.
- TrpV1 receptors are located in temperature-sensitive cells throughout the body, including the hand.
- A change in temperature or the presence of painful stimuli causes a conformational change in the TrpV1 protein.
- When a cell is stimulated, it releases molecules that bind to TrpV1 receptors, inducing the same conformational change and activating the cell.
- Fast (A-beta), medium (A-delta), and slow fibers are present in nerves that transmit signals from the hand to the brain.
- Fast fibers are large in diameter and well-myelinated, allowing for quick signal transmission and withdrawal from painful or hot stimuli.
- Medium fibers are smaller in diameter and less myelinated, resulting in slower signal transmission and the sensation of immediate pain.
- Slow fibers are very small in diameter and unmyelinated, sending signals very slowly and causing a lingering sensation of pain.
- The workers discussed in the text use their hands and are exposed to temperature and pain stimuli, highlighting the importance of the hand's pain and temperature sensing system.
- The TrpV1 receptor is the same receptor that responds to both temperature and pain stimuli, as demonstrated by the effects of capsaicin, a pain-inducing compound found in jalapenos.
- When eating a jalapeno, capsaicin is released from the cells and binds to TrpV1 receptors in the tongue, triggering the same response as a change in temperature.
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Description
Test your knowledge about our ability to sense pain and temperature, also known as nociception and thermoception. Learn about the specialized receptors in our body that enable us to perceive these sensations.