Senna Flashcards
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Questions and Answers

Which of the following are brand names for Senna? (Select all that apply)

  • Motrin®
  • Senokot® (correct)
  • Ex-lax® (correct)
  • Tylenol®

What is the generic name for Senna?

senna

What are some sound alike/look alike issues with Senna?

Ex-lax Ultra® (bisacodyl) and Ex-Lax Maximum strength® (sennosides)

What is the therapeutic class of Senna?

<p>Stimulant laxative</p> Signup and view all the answers

Senna increases the rate of colonic motility through direct action on the intestinal ______.

<p>mucosa</p> Signup and view all the answers

What are common indications for using Senna?

<p>Short-term treatment of constipation; evacuation of the bowel prior to rectal or bowel examination</p> Signup and view all the answers

What are some absolute contraindications for using Senna?

<p>Intestinal obstruction, acute intestinal inflammation, appendicitis, ulcerative colitis, abdominal pain of unknown origin</p> Signup and view all the answers

What dosage forms are available for Senna?

<p>tablet, syrup, liquid</p> Signup and view all the answers

What is the usual dosing for adults using Senna for constipation?

<p>Sennosides 15 mg once daily (maximum: 70-100 mg/day, divided twice daily)</p> Signup and view all the answers

What are common adverse effects of Senna?

<p>Abdominal cramps, diarrhea, nausea, vomiting</p> Signup and view all the answers

When should Senna be administered?

<p>Once daily doses should be taken at bedtime</p> Signup and view all the answers

What clinical teaching should be given regarding the use of Senna?

<p>Stop use and contact prescriber if you develop nausea, vomiting, persistent diarrhea, or abdominal cramps.</p> Signup and view all the answers

Study Notes

Senna Overview

  • Known brands: Senokot®, Ex-lax®
  • Generic name: senna (pronounced SEN na)

Sound Alike/Look Alike Issues

  • Similar products: Ex-lax Ultra® (bisacodyl), Ex-Lax Maximum Strength® (sennosides)

Therapeutic Classification

  • Classified as a stimulant laxative, used to induce bowel movements

Mechanism of Action

  • Directly acts on the intestinal mucosa
  • Increases colonic motility and enhances transit
  • Inhibits secretion of water and electrolytes in the intestines

Indications for Use

  • Short-term treatment of constipation
  • Bowel evacuation before rectal or bowel examinations

Contraindications and Warnings

  • Not suitable for patients with:
    • Intestinal obstruction
    • Acute intestinal inflammation (e.g., Crohn's disease, appendicitis symptoms)
    • Ulcerative colitis
    • Abdominal pain without known cause
  • Has potential black box warnings for severe complications

Available Dosage Forms

  • Available as tablets, syrup, and liquid formulations

Usual Dosing Guidelines

  • For adults (≥12 years):
    • Constipation: Sennosides 15 mg once daily, with a maximum of 70-100 mg/day divided twice
    • Bowel evacuation: Sennosides 130 mg taken between 2-4 PM prior to procedures

Common and Serious Side Effects

  • Common effects include: abdominal cramps, nausea, diarrhea, vomiting
  • Serious effects may involve: nephritis, hepatotoxicity, and melanotic pigmentation of the colonic mucosa

Administration Instructions

  • Recommended to take doses at bedtime
  • Granules can be consumed plain, mixed with food, or dissolved in liquids

Clinical Teaching Points

  • Advise to stop usage and consult a healthcare provider if nausea, vomiting, persistent diarrhea, or abdominal cramps occur
  • If constipation worsens or no relief is experienced, recommend contacting a healthcare provider

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Test your knowledge with these flashcards on Senna, including its brand names, generic name, and therapeutic class. Explore its mechanism of action and sound-alike/look-alike issues. Perfect for students and professionals in pharmacology.

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