54 Questions
Which form of selenium is associated with the antioxidant and anticarcinogenic properties?
Selenocysteine
Which enzyme is involved in the reduction of oxidized glutathione (GSSG) back to its active form (GSH)?
Glutathione reductase
Which cellular process often produces NADPH, the coenzyme involved in regenerating GSH from GSSG?
Pentose phosphate pathway
Which selenium species is associated with enzymes such as iodothyronine deiodinase and thioredoxin reductase?
Selenocysteine
Which element is linked to the development of gout?
Molybdenum
What is the role of xanthine oxidase in the body?
Participating in purine metabolism
Which element is essential for the catalytic activity of urease?
Nickel
What is the main source of fluoride?
Water and tea
Which element is used in the treatment of manic-depressive patients?
Lithium
What is the role of iodine in the body?
Synthesis of thyroid hormones
Which element is used in the treatment of rheumatoid arthritis?
Gold
What is the main source of molybdenum?
Legumes
Which element is associated with Wilson's disease?
Molybdenum
What is the role of selenium in the body?
Essential for thyroid gland functioning
Which element is found in metal alloys and batteries?
Nickel
Which element is linked to the accumulation of iron in the heart?
Cobalt
Which enzyme is a selenoprotein that is crucial for maintaining cellular redox homeostasis?
Thioredoxin reductase
Which disease is associated with selenium deficiency and dilated cardiomyopathy?
Keshan disease
Which selenium-containing enzyme is essential for protecting against oxidative stress and DNA synthesis?
Thioredoxin reductase
Selenium deficiency can impact the integrity and health of which tissue, potentially contributing to osteoarthritis?
Cartilage
Which enzyme helps neutralize reactive oxygen species and may leave joint tissues susceptible to oxidative damage in the case of selenium deficiency?
Glutathione peroxidase
Which physiological condition can manifest in childhood due to selenium deficiency?
Stunted growth and skeletal deformities
Which enzyme is involved in the removal of iodine atoms from thyroid hormones and is important in selenium metabolism?
Deiodinase
Which enzyme is directly incorporated with selenium into its catalytic site?
Thioredoxin reductase
Which selenoprotein plays a role in cellular defense against oxidative stress?
Glutathione peroxidase
Which enzyme is a selenoprotein that is implicated in protection against oxidative stress and DNA synthesis?
Thioredoxin reductase
Which enzyme is a selenoprotein that is essential for maintaining cellular redox homeostasis?
Thioredoxin reductase
Which form of selenium is associated with the antioxidant and anticarcinogenic properties?
Selenomethionine
Which enzyme is involved in the reduction of oxidized glutathione (GSSG) back to its active form (GSH)?
Glutathione reductase
Which enzyme is directly incorporated with selenium into its catalytic site?
Thioredoxin reductase
Which physiological condition can manifest in childhood due to selenium deficiency?
Keshan disease
Which element is associated with the development of gout?
Molybdenum
Which element is used in the treatment of bipolar disorder?
Lithium
Which element is essential for thyroid gland functioning, biosynthesis, and metabolism?
Iodine
Which element is linked to the accumulation of iron in the heart?
Cobalt
Which element is associated with Wilson’s disease?
Molybdenum
Which element is found in metal alloys, batteries, and oils?
Nickel
Which element is used in the treatment of rheumatoid arthritis?
Gold
Which element is essential for the catalytic activity of urease?
Nickel
Which element is used to prevent tooth decay and increases remineralization?
Fluoride
Which element is associated with HP-associated Gastric Disease and Alzheimer's disease?
Selenium
Which element is high in liver, skeleton, and kidneys and is eliminated via urine?
Molybdenum
Which element is associated with the synthesis of thyroid hormones T3 and T4?
Iodine
Which enzyme is a selenoprotein that contains selenocysteine and is involved in reducing thioredoxin and maintaining antioxidant defense?
Glutathione peroxidase
Which disease is associated with selenium deficiency and potentially leads to stunted growth and skeletal deformities in childhood?
Keshan disease
Which enzyme is directly incorporated with selenium into its catalytic site?
Thioredoxin reductase
Which tissue's integrity and health may be impacted by selenium deficiency, potentially contributing to osteoarthritis?
Cartilage
Which enzyme is involved in the removal of iodine atoms from thyroid hormones and is important in selenium metabolism?
Deiodinase
Which element is found in metal alloys and batteries?
Lithium
What is the role of xanthine oxidase in the body?
Uric acid formation
Which element is associated with Wilson's disease?
Copper
Which physiological condition can manifest in childhood due to selenium deficiency?
Keshan disease
Which enzyme is a selenoprotein that is implicated in protection against oxidative stress and DNA synthesis?
Glutathione peroxidase
Which element is essential for the catalytic activity of urease?
Nickel
Study Notes
Selenium and Its Role in Cellular Health
- Glutathione cycle maintains balance between GSH and GSSG for cellular defense against oxidative stress
- Deiodination involves removal of iodine atoms from thyroid hormones and is important in selenium metabolism
- Thioredoxin reductase is a selenoprotein that plays a crucial role in cellular redox homeostasis
- Thioredoxin reductase contains selenocysteine and is involved in reducing thioredoxin and maintaining antioxidant defense
- Selenium is essential for thioredoxin reductase function and is directly incorporated into its catalytic site
- Thioredoxin reductase is implicated in physiological processes such as protection against oxidative stress and DNA synthesis
- Keshan disease is a potentially serious heart condition associated with selenium deficiency and dilated cardiomyopathy
- Selenium deficiency has been identified as a contributing factor in the development of Keshan disease
- Selenium is essential for selenoproteins, including glutathione peroxidases, which play a role in antioxidant defense
- Selenium deficiency may impact the integrity and health of cartilage, potentially contributing to osteoarthritis
- Glutathione peroxidases help neutralize reactive oxygen species and selenium deficiency may leave joint tissues susceptible to oxidative damage
- Selenium deficiency can manifest in childhood, leading to stunted growth and skeletal deformities
Selenium and Its Role in Cellular Health
- Glutathione cycle maintains balance between GSH and GSSG for cellular defense against oxidative stress
- Deiodination involves removal of iodine atoms from thyroid hormones and is important in selenium metabolism
- Thioredoxin reductase is a selenoprotein that plays a crucial role in cellular redox homeostasis
- Thioredoxin reductase contains selenocysteine and is involved in reducing thioredoxin and maintaining antioxidant defense
- Selenium is essential for thioredoxin reductase function and is directly incorporated into its catalytic site
- Thioredoxin reductase is implicated in physiological processes such as protection against oxidative stress and DNA synthesis
- Keshan disease is a potentially serious heart condition associated with selenium deficiency and dilated cardiomyopathy
- Selenium deficiency has been identified as a contributing factor in the development of Keshan disease
- Selenium is essential for selenoproteins, including glutathione peroxidases, which play a role in antioxidant defense
- Selenium deficiency may impact the integrity and health of cartilage, potentially contributing to osteoarthritis
- Glutathione peroxidases help neutralize reactive oxygen species and selenium deficiency may leave joint tissues susceptible to oxidative damage
- Selenium deficiency can manifest in childhood, leading to stunted growth and skeletal deformities
Test your knowledge of selenium and its crucial role in cellular health with this quiz. Explore its involvement in the glutathione cycle, deiodination, thioredoxin reductase function, and its impact on conditions like Keshan disease and osteoarthritis.
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