Selenium and Cellular Health Quiz
54 Questions
2 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which form of selenium is associated with the antioxidant and anticarcinogenic properties?

  • Selenite
  • Selenomethionine
  • Selenate
  • Selenocysteine (correct)
  • Which enzyme is involved in the reduction of oxidized glutathione (GSSG) back to its active form (GSH)?

  • Iodothyronine deiodinase
  • Glutathione peroxidase
  • Thioredoxin reductase
  • Glutathione reductase (correct)
  • Which cellular process often produces NADPH, the coenzyme involved in regenerating GSH from GSSG?

  • Electron transport chain
  • Pentose phosphate pathway (correct)
  • Krebs cycle
  • Glycolysis
  • Which selenium species is associated with enzymes such as iodothyronine deiodinase and thioredoxin reductase?

    <p>Selenocysteine</p> Signup and view all the answers

    Which element is linked to the development of gout?

    <p>Molybdenum</p> Signup and view all the answers

    What is the role of xanthine oxidase in the body?

    <p>Participating in purine metabolism</p> Signup and view all the answers

    Which element is essential for the catalytic activity of urease?

    <p>Nickel</p> Signup and view all the answers

    What is the main source of fluoride?

    <p>Water and tea</p> Signup and view all the answers

    Which element is used in the treatment of manic-depressive patients?

    <p>Lithium</p> Signup and view all the answers

    What is the role of iodine in the body?

    <p>Synthesis of thyroid hormones</p> Signup and view all the answers

    Which element is used in the treatment of rheumatoid arthritis?

    <p>Gold</p> Signup and view all the answers

    What is the main source of molybdenum?

    <p>Legumes</p> Signup and view all the answers

    Which element is associated with Wilson's disease?

    <p>Molybdenum</p> Signup and view all the answers

    What is the role of selenium in the body?

    <p>Essential for thyroid gland functioning</p> Signup and view all the answers

    Which element is found in metal alloys and batteries?

    <p>Nickel</p> Signup and view all the answers

    Which element is linked to the accumulation of iron in the heart?

    <p>Cobalt</p> Signup and view all the answers

    Which enzyme is a selenoprotein that is crucial for maintaining cellular redox homeostasis?

    <p>Thioredoxin reductase</p> Signup and view all the answers

    Which disease is associated with selenium deficiency and dilated cardiomyopathy?

    <p>Keshan disease</p> Signup and view all the answers

    Which selenium-containing enzyme is essential for protecting against oxidative stress and DNA synthesis?

    <p>Thioredoxin reductase</p> Signup and view all the answers

    Selenium deficiency can impact the integrity and health of which tissue, potentially contributing to osteoarthritis?

    <p>Cartilage</p> Signup and view all the answers

    Which enzyme helps neutralize reactive oxygen species and may leave joint tissues susceptible to oxidative damage in the case of selenium deficiency?

    <p>Glutathione peroxidase</p> Signup and view all the answers

    Which physiological condition can manifest in childhood due to selenium deficiency?

    <p>Stunted growth and skeletal deformities</p> Signup and view all the answers

    Which enzyme is involved in the removal of iodine atoms from thyroid hormones and is important in selenium metabolism?

    <p>Deiodinase</p> Signup and view all the answers

    Which enzyme is directly incorporated with selenium into its catalytic site?

    <p>Thioredoxin reductase</p> Signup and view all the answers

    Which selenoprotein plays a role in cellular defense against oxidative stress?

    <p>Glutathione peroxidase</p> Signup and view all the answers

    Which enzyme is a selenoprotein that is implicated in protection against oxidative stress and DNA synthesis?

    <p>Thioredoxin reductase</p> Signup and view all the answers

    Which enzyme is a selenoprotein that is essential for maintaining cellular redox homeostasis?

    <p>Thioredoxin reductase</p> Signup and view all the answers

    Which form of selenium is associated with the antioxidant and anticarcinogenic properties?

    <p>Selenomethionine</p> Signup and view all the answers

    Which enzyme is involved in the reduction of oxidized glutathione (GSSG) back to its active form (GSH)?

    <p>Glutathione reductase</p> Signup and view all the answers

    Which enzyme is directly incorporated with selenium into its catalytic site?

    <p>Thioredoxin reductase</p> Signup and view all the answers

    Which physiological condition can manifest in childhood due to selenium deficiency?

    <p>Keshan disease</p> Signup and view all the answers

    Which element is associated with the development of gout?

    <p>Molybdenum</p> Signup and view all the answers

    Which element is used in the treatment of bipolar disorder?

    <p>Lithium</p> Signup and view all the answers

    Which element is essential for thyroid gland functioning, biosynthesis, and metabolism?

    <p>Iodine</p> Signup and view all the answers

    Which element is linked to the accumulation of iron in the heart?

    <p>Cobalt</p> Signup and view all the answers

    Which element is associated with Wilson’s disease?

    <p>Molybdenum</p> Signup and view all the answers

    Which element is found in metal alloys, batteries, and oils?

    <p>Nickel</p> Signup and view all the answers

    Which element is used in the treatment of rheumatoid arthritis?

    <p>Gold</p> Signup and view all the answers

    Which element is essential for the catalytic activity of urease?

    <p>Nickel</p> Signup and view all the answers

    Which element is used to prevent tooth decay and increases remineralization?

    <p>Fluoride</p> Signup and view all the answers

    Which element is associated with HP-associated Gastric Disease and Alzheimer's disease?

    <p>Selenium</p> Signup and view all the answers

    Which element is high in liver, skeleton, and kidneys and is eliminated via urine?

    <p>Molybdenum</p> Signup and view all the answers

    Which element is associated with the synthesis of thyroid hormones T3 and T4?

    <p>Iodine</p> Signup and view all the answers

    Which enzyme is a selenoprotein that contains selenocysteine and is involved in reducing thioredoxin and maintaining antioxidant defense?

    <p>Glutathione peroxidase</p> Signup and view all the answers

    Which disease is associated with selenium deficiency and potentially leads to stunted growth and skeletal deformities in childhood?

    <p>Keshan disease</p> Signup and view all the answers

    Which enzyme is directly incorporated with selenium into its catalytic site?

    <p>Thioredoxin reductase</p> Signup and view all the answers

    Which tissue's integrity and health may be impacted by selenium deficiency, potentially contributing to osteoarthritis?

    <p>Cartilage</p> Signup and view all the answers

    Which enzyme is involved in the removal of iodine atoms from thyroid hormones and is important in selenium metabolism?

    <p>Deiodinase</p> Signup and view all the answers

    Which element is found in metal alloys and batteries?

    <p>Lithium</p> Signup and view all the answers

    What is the role of xanthine oxidase in the body?

    <p>Uric acid formation</p> Signup and view all the answers

    Which element is associated with Wilson's disease?

    <p>Copper</p> Signup and view all the answers

    Which physiological condition can manifest in childhood due to selenium deficiency?

    <p>Keshan disease</p> Signup and view all the answers

    Which enzyme is a selenoprotein that is implicated in protection against oxidative stress and DNA synthesis?

    <p>Glutathione peroxidase</p> Signup and view all the answers

    Which element is essential for the catalytic activity of urease?

    <p>Nickel</p> Signup and view all the answers

    Study Notes

    Selenium and Its Role in Cellular Health

    • Glutathione cycle maintains balance between GSH and GSSG for cellular defense against oxidative stress
    • Deiodination involves removal of iodine atoms from thyroid hormones and is important in selenium metabolism
    • Thioredoxin reductase is a selenoprotein that plays a crucial role in cellular redox homeostasis
    • Thioredoxin reductase contains selenocysteine and is involved in reducing thioredoxin and maintaining antioxidant defense
    • Selenium is essential for thioredoxin reductase function and is directly incorporated into its catalytic site
    • Thioredoxin reductase is implicated in physiological processes such as protection against oxidative stress and DNA synthesis
    • Keshan disease is a potentially serious heart condition associated with selenium deficiency and dilated cardiomyopathy
    • Selenium deficiency has been identified as a contributing factor in the development of Keshan disease
    • Selenium is essential for selenoproteins, including glutathione peroxidases, which play a role in antioxidant defense
    • Selenium deficiency may impact the integrity and health of cartilage, potentially contributing to osteoarthritis
    • Glutathione peroxidases help neutralize reactive oxygen species and selenium deficiency may leave joint tissues susceptible to oxidative damage
    • Selenium deficiency can manifest in childhood, leading to stunted growth and skeletal deformities

    Selenium and Its Role in Cellular Health

    • Glutathione cycle maintains balance between GSH and GSSG for cellular defense against oxidative stress
    • Deiodination involves removal of iodine atoms from thyroid hormones and is important in selenium metabolism
    • Thioredoxin reductase is a selenoprotein that plays a crucial role in cellular redox homeostasis
    • Thioredoxin reductase contains selenocysteine and is involved in reducing thioredoxin and maintaining antioxidant defense
    • Selenium is essential for thioredoxin reductase function and is directly incorporated into its catalytic site
    • Thioredoxin reductase is implicated in physiological processes such as protection against oxidative stress and DNA synthesis
    • Keshan disease is a potentially serious heart condition associated with selenium deficiency and dilated cardiomyopathy
    • Selenium deficiency has been identified as a contributing factor in the development of Keshan disease
    • Selenium is essential for selenoproteins, including glutathione peroxidases, which play a role in antioxidant defense
    • Selenium deficiency may impact the integrity and health of cartilage, potentially contributing to osteoarthritis
    • Glutathione peroxidases help neutralize reactive oxygen species and selenium deficiency may leave joint tissues susceptible to oxidative damage
    • Selenium deficiency can manifest in childhood, leading to stunted growth and skeletal deformities

    Studying That Suits You

    Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

    Quiz Team

    Related Documents

    selenium etc.docx

    Description

    Test your knowledge of selenium and its crucial role in cellular health with this quiz. Explore its involvement in the glutathione cycle, deiodination, thioredoxin reductase function, and its impact on conditions like Keshan disease and osteoarthritis.

    More Like This

    Use Quizgecko on...
    Browser
    Browser