Seizure Semiology: Auras & Localization

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Questions and Answers

What is the primary focus of seizure semiology?

  • Analyzing the genetic causes of epilepsy
  • Studying observable clinical signs and symptoms during a seizure (correct)
  • Developing new medications to prevent seizures
  • Studying the financial impact of seizures on patients

What is the purpose of studying observable clinical signs and symptoms during a seizure?

  • To provide emotional support to individuals experiencing seizures
  • To predict the weather patterns that might trigger seizures
  • To locate the part of the brain where seizures start (correct)
  • To determine the cost of treating seizures

According to the content, which of the following are especially important for localization during a seizure?

  • Dietary habits and exercise routines
  • Aura and motor signs (correct)
  • Family history and genetic predispositions
  • Financial records and medical bills

Which type of somatosensory aura is commonly experienced during a seizure?

<p>Tingling and numbness (A)</p> Signup and view all the answers

What type of aura involves simple sounds or voices/music?

<p>Auditory (C)</p> Signup and view all the answers

Which lobe is typically involved in olfactory auras?

<p>Temporal lobe (D)</p> Signup and view all the answers

A person experiencing flashes of light or static is most likely having what kind of aura?

<p>Visual (B)</p> Signup and view all the answers

What brain regions are associated with abdominal auras?

<p>Insula, mesial temporal (D)</p> Signup and view all the answers

Which of the following is associated with psychic auras?

<p>Emotions and déjà vu (D)</p> Signup and view all the answers

Palpitations and piloerection are signs of what type of aura?

<p>Autonomic (D)</p> Signup and view all the answers

During a seizure, if a patient's head and eyes deviate, it is typically __________ to the seizure focus.

<p>Contralateral (A)</p> Signup and view all the answers

During a seizure, if a patient has unilateral clonic activity, it is typically __________.

<p>Contralateral (C)</p> Signup and view all the answers

Dystonic posturing during a seizure is most commonly observed in which type of epilepsy?

<p>Temporal Lobe Epilepsy (B)</p> Signup and view all the answers

If a patient exhibits the 'Figure-of-4' sign during a seizure, which arm is extended?

<p>Extended arm is contralateral (B)</p> Signup and view all the answers

Ictal spitting or vomiting during a seizure is most often associated with which hemisphere?

<p>Non-dominant hemisphere (C)</p> Signup and view all the answers

Which hemisphere is indicated by ictal speech during a seizure?

<p>Non-dominant (A)</p> Signup and view all the answers

Which hemisphere is indicated by speech arrest during a seizure?

<p>Dominant (B)</p> Signup and view all the answers

What is Todd's paralysis?

<p>Weakness on one side of the body after a seizure (C)</p> Signup and view all the answers

Postictal aphasia suggests involvement of which hemisphere?

<p>Dominant (C)</p> Signup and view all the answers

Postictal nose wiping is typically __________.

<p>Ipsilateral to focus (B)</p> Signup and view all the answers

In seizure semiology, what is a key application of studying aura and motor signs?

<p>Pinpointing the brain region where the seizure originates. (D)</p> Signup and view all the answers

A patient reports experiencing a sensation of tingling and numbness during a seizure. Which brain region is most likely involved?

<p>Contralateral somatosensory cortex (parietal lobe) (D)</p> Signup and view all the answers

Which neural structure is most likely implicated in a patient experiencing olfactory auras before a seizure?

<p>Mesial temporal (amygdala) (D)</p> Signup and view all the answers

A patient undergoing a seizure exhibits a 'Figure-of-4' sign on their left side. What does this indicate about the seizure focus?

<p>The seizure focus is contralateral to the extended arm. (A)</p> Signup and view all the answers

A patient is observed to have violent, thrashing movements during a seizure. Which area of the brain is most likely involved?

<p>Frontal lobe or SMA (D)</p> Signup and view all the answers

During a neurological assessment, a patient suddenly experiences a gustatory aura. Which area of the brain is likely involved?

<p>Parietal operculum. (C)</p> Signup and view all the answers

What is the significance of unilateral eye blinking as an ictal sign during a seizure?

<p>It indicates ipsilateral seizure focus. (C)</p> Signup and view all the answers

A patient demonstrates speech arrest during a seizure. Which of the following is most likely?

<p>Involvement of the dominant hemisphere. (D)</p> Signup and view all the answers

A patient exhibits postictal coughing and water drinking. Which hemisphere is most likely involved?

<p>Non-dominant hemisphere. (C)</p> Signup and view all the answers

Which brain area is most likely involved when a patient reports experiencing a sense of déjà vu during a seizure?

<p>Amygdala (A)</p> Signup and view all the answers

A patient experiences autonomic auras during a seizure. Which of the following is least likely to be involved?

<p>Occipital cortex (A)</p> Signup and view all the answers

What is the significance of the 'rising sensation' in the abdomen as an aura symptom during a seizure?

<p>It indicates temporal lobe epilepsy. (A)</p> Signup and view all the answers

A patient's head and eyes deviate to the left during a seizure. What does this indicate?

<p>Seizure focus is in the right hemisphere. (C)</p> Signup and view all the answers

A patient exhibits ictal speech during a seizure. Which hemisphere is most likely involved?

<p>Non-dominant hemisphere. (D)</p> Signup and view all the answers

What is the primary significance of postictal lateralizing signs in seizure semiology?

<p>To localize the epileptogenic zone (B)</p> Signup and view all the answers

During a seizure, a patient is observed making repetitive hand and mouth movements. Which area of the brain is most likely involved?

<p>Both the temporal and frontal lobes (B)</p> Signup and view all the answers

A patient experiences localized weakness on the left side of their body following a seizure. Which of the following is most likely?

<p>Seizure focus in the right hemisphere (D)</p> Signup and view all the answers

A patient exhibits dystonic posturing during a seizure. Which condition is this most commonly observed in?

<p>Temporal lobe epilepsy (D)</p> Signup and view all the answers

After a seizure, a patient exhibits aphasia. Which hemisphere is most likely involved?

<p>Dominant hemisphere (C)</p> Signup and view all the answers

During an evaluation, a patient has gelastic seizures. What underlying condition should be suspected?

<p>Hypothalamic hamartoma. (D)</p> Signup and view all the answers

Flashcards

Seizure Semiology

The study of observable clinical signs and symptoms during a seizure, which helps locate where seizures start in the brain.

Somatosensory Aura

Tingling or numbness. It localizes to the contralateral somatosensory cortex (parietal lobe).

Auditory Aura

Simple sounds or voices/music. It localizes to the auditory association cortex including Heschl's gyrus.

Olfactory Aura

Smells. It localizes to the mesial temporal areas, orbitofrontal cortex, and insula.

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Visual Aura

Flashes or static visual disturbances. It localizes to the occipital cortex (areas 17, 18, 19).

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Abdominal Aura

Rising sensation in the abdomen. It localizes to the insula and mesial temporal areas.

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Psychic Aura

Emotions, déjà vu experiences. It localizes to the amygdala, hippocampus, and temporal cortex.

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Autonomic Aura

Palpitations, piloerection, genital sensations. It localizes to the insula, cingulate, and SMA.

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Head/Eye Deviation (Ictal)

Deviation contralateral to the seizure focus.

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Unilateral Clonic Activity (Ictal)

Clonic activity contralateral to the seizure focus.

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Dystonic Posturing (Ictal)

Contralateral dystonic posturing, especially in Temporal Lobe Epilepsy (TLE).

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"Figure-of-4" Sign (Ictal)

Extended arm is contralateral to seizure focus.

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Ictal Spitting/Vomiting

Occurs in the right or non-dominant hemisphere.

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Unilateral Eye Blinking (Ictal)

Occurs ipsilateral to the seizure focus.

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Ictal Speech

Occurs in the non-dominant hemisphere.

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Speech Arrest (Ictal)

Suggests the dominant hemisphere.

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Todd's Paralysis (Post-Ictal)

Weakness on one side, contralateral to the seizure focus.

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Postictal Aphasia

Suggests dominant hemisphere involvement.

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Postictal Nose Wiping

Often seen in Temporal Lobe Epilepsy (TLE) and ipsilateral to seizure focus.

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Postictal Cough/Water Drinking

Occurs in the non-dominant hemisphere.

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Hypermotor Seizure

Violent, thrashing movements often originating from the frontal lobe or supplementary motor area (SMA).

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Automotor Seizure

Repetitive hand or mouth movements, indicating temporal or frontal lobe involvement.

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Gelastic Seizure

Laughing seizures, often non-lateralizing, and seen in hypothalamic hamartomas.

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Study Notes

  • Seizure semiology is the study of clinical signs/symptoms during a seizure.
  • Seizure semiology aids in locating the brain's epileptogenic zone, where seizures begin.
  • Auras and motor signs play a key role in localization.

Common Auras & Localization

  • Somatosensory auras manifest as tingling/numbness in the contralateral somatosensory cortex (parietal lobe).
  • Auditory auras involve simple sounds (Heschls gyrus) or voices/music (auditory association cortex).
  • Olfactory auras involve smell in the mesial temporal (amygdala), orbitofrontal, or insula regions.
  • Gustatory auras involve taste, localized to the parietal operculum, insula, or mesial temporal regions.
  • Visual auras can be flashes or static and are linked to the occipital cortex (areas 17, 18, 19), while scenes/people are linked to the temporo-occipital region.
  • Abdominal auras have a rising sensation linked to the insula or mesial temporal lobe, often seen in temporal lobe epilepsy.
  • Psychic auras can manifest as emotions or déjà vu, linked to the amygdala, hippocampus, or temporal cortex.
  • Autonomic auras include palpitations, piloerection, or genital sensations, linked to the insula, cingulate, or SMA.

Lateralizing Ictal Signs (During Seizure)

  • Head/Eye Deviation shifts contralaterally to the seizure focus.
  • Unilateral Clonic Activity occurs contralaterally.
  • Dystonic Posturing presents contralaterally, especially in temporal lobe epilepsy (TLE).
  • The Figure-of-4 Sign, where the extended arm is contralateral.
  • Ictal Spitting/Vomiting originates in the right or non-dominant hemisphere.
  • Unilateral Eye Blinking occurs ipsilaterally.
  • Ictal Speech disturbances originate in the non-dominant hemisphere.
  • Speech Arrest points to the dominant hemisphere.

Post-Ictal Lateralizing Signs (After Seizure)

  • Todd's Paralysis causes weakness on one side, contralateral to the seizure focus.
  • Postictal Aphasia suggests involvement of the dominant hemisphere.
  • Postictal Nose Wiping is ipsilateral, especially in temporal lobe epilepsy (TLE).
  • Postictal Cough or Water Drinking occurs in the non-dominant hemisphere.

Complex Motor Seizures

  • Hypermotor seizures involve violent, thrashing movements and originate in the frontal lobe or SMA.
  • Automotor seizures involve repetitive hand/mouth movements and originate in the temporal or frontal lobe.
  • Gelastic seizures (laughing) are often non-lateralizing and seen in hypothalamic hamartomas.

Quick Summary Chart of Seizure Signs/Symptoms and Localization

  • Déjà vu, fear, or abdominal auras localize to the mesial temporal lobe.
  • Visual auras (flashes) localize to the occipital cortex.
  • Auditory hallucinations localize to the temporal lobe.
  • Ictal spitting or vomiting localizes to the right/non-dominant hemisphere.
  • Postictal nose wiping localizes to the ipsilateral side.
  • Dystonic posturing localizes to the contralateral side.
  • Todd's paralysis localizes to the contralateral side.

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