Sedatives & Hypnotics for Sleep Wake Disorders

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37 Questions

Which medication is classified as a short-intermediate acting benzo receptor agonist?

Eszopiclone

What type of medication is zolpidem?

Short-intermediate acting benzo receptor agonist

Which one of these medications would be a first-line choice for treating primary insomnia?

Zolpidem

What is the main use of temazepam in the context of sleep disorders?

Difficulty falling or remaining asleep

Which medication would be most suitable for a patient experiencing frequent nocturnal awakenings?

Zaleplon

Which of the listed medications is NOT recommended for long-term use in treating insomnia?

Temazepam

What distinguishes ramelteon from the other medications mentioned?

It is a melatonin receptor agonist

In which phase of sleep is Eszopiclone (Lunesta) commonly used?

Maintenance

True or False: Over-the-counter (OTC) sedative/hypnotics can lead to rapidly developing tolerance to their sedating effects.

True

What is the main MOA (Mechanism of Action) of Ramelteon?

Selective melatonin 1 and 2 agonist

Which of the following is a long-lasting agent and may cause excessive drowsiness?

Flurazepam (Dalmane)

Why is Flurazepam generally avoided in older adults?

Excessive drowsiness and long-acting

'Priapism', a persistent and painful erection, is commonly associated with which antidepressant used for sleep?

Doxepin (Sinequan)

'Armodafinil (Nuvigil)' is primarily indicated for which condition?

Excessive daytime sleepiness associated with OSA

Why is Zaleplon not suitable for long-term use?

Short half-life and quick onset of action

Which medication helps with staying asleep?

Eszopiclone

Which medication is approved for short-term insomnia and has a short half-life?

Zolpidem

Which medication is a GABA-PAM (Positive Allosteric Modulator) and can be used long term?

Zaleplon

Which medication is known for causing anterograde amnesia, hallucinations, and parasomnias?

Zolpidem

Which medication is a selective Melatonin agonist and does not lead to tolerance or dependence?

Ramelteon

Which medication is recommended with an empty stomach for better absorption?

Zaleplon

Which medication can be associated with increased fall risk and GI effects in addition to anterograde amnesia and hallucinations?

Zolpidem

Which medication should avoid use with the elderly due to moderate anticholinergic effects?

Diphenhydramine

What is the first-line treatment for Restless Legs Syndrome (RLS)?

Dopamine agonists

Which of the following is a risk factor for Restless Legs Syndrome?

Antidepressants

What characteristic differentiates Restless Legs Syndrome from other conditions?

Relief with movement

What is the treatment for insomnia recommended for elderly patients?

Trazodone and Remeron

What can trigger symptoms consistent with Restless Leg Syndrome (RLS)?

Activating serotonergic agents like Effexor

What is the characteristic that worsens Restless Legs Syndrome (RLS)?

Inactivity

What treatment is recommended for RLS when dopamine agonists are ineffective?

Gabapentin; pregabalin(Lyrica)

What disorder is characterized by impaired sleep and daytime functioning along with involuntary jerking movements of limbs during sleep?

Periodic Limb Movements of Sleep (PLMS)

What is the first-line treatment for narcolepsy with cataplexy?

Sodium oxybate

Which medication should be avoided with alcohol and other CNS depressants due to its interactions?

Temazepam

Which of the following drugs is known for causing memory impairment, ataxia, and rebound insomnia in elderly patients?

Trazodone

What is the characteristic feature of narcolepsy involving brief episodes of sudden bilateral loss of muscle tone?

Cataplexy

Which drug is classified as a REM suppression drug for narcolepsy management?

Prozac

In the context of narcolepsy, what is the role of hypocretin-producing neurons in the hypothalamus?

Control of muscle tone

Test your knowledge on sedatives, hypnotics, and sleep disorders like insomnia and hypersomnia. Learn about the stages of the sleep-wake cycle, key differences between REM and NREM sleep, and common types of insomnia. Explore the concepts of sleep-onset, sleep maintenance, and sleep offset insomnia.

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